Sensitivity of Global Translation to mTOR Inhibition in REN Cells Depends on the Equilibrium between eIF4E and 4E-BP1

por Grosso, Stefano, Pesce, Elisa, Brina, Daniela, Beugnet, Anne, Loreni, Fabrizio, Biffo, Stefano
Publicado 2011

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP

por Esposito, Davide, Crescenzi, Elvira, Sagar, Vinay, Loreni, Fabrizio, Russo, Annapina, Russo, Giulia
Publicado 2014

PIM1 destabilization activates a p53-dependent response to ribosomal stress in cancer cells

por Sagar, Vinay, Caldarola, Sara, Aria, Valentina, Monteleone, Valentina, Fuoco, Claudia, Gargioli, Cesare, Cannata, Stefano, Loreni, Fabrizio
Publicado 2016

Combined therapy with RAD001 e BEZ235 overcomes resistance of PET immortalized cell lines to mTOR inhibition

por Passacantilli, Ilaria, Capurso, Gabriele, Archibugi, Livia, Calabretta, Sara, Caldarola, Sara, Loreni, Fabrizio, Fave, Gianfranco Delle, Sette, Claudio
Publicado 2014

Ribosomal stress activates eEF2K–eEF2 pathway causing translation elongation inhibition and recruitment of Terminal Oligopyrimidine (TOP) mRNAs on polysomes

por Gismondi, Angelo, Caldarola, Sara, Lisi, Gaia, Juli, Giada, Chellini, Lidia, Iadevaia, Valentina, Proud, Christopher G., Loreni, Fabrizio
Publicado 2014

CPEB1 restrains proliferation of Glioblastoma cells through the regulation of p27(Kip1) mRNA translation

por Galardi, Silvia, Petretich, Massimo, Pinna, Guillaume, D’Amico, Silvia, Loreni, Fabrizio, Michienzi, Alessandro, Groisman, Irina, Ciafrè, Silvia Anna
Publicado 2016

Depletion of ribosomal protein S19 causes a reduction of rRNA synthesis

por Juli, Giada, Gismondi, Angelo, Monteleone, Valentina, Caldarola, Sara, Iadevaia, Valentina, Aspesi, Anna, Dianzani, Irma, Proud, Christopher G., Loreni, Fabrizio
Publicado 2016

Lymphoblastoid cell lines from Diamond Blackfan anaemia patients exhibit a full ribosomal stress phenotype that is rescued by gene therapy

por Aspesi, Anna, Monteleone, Valentina, Betti, Marta, Actis, Chiara, Morleo, Giulia, Sculco, Marika, Guarrera, Simonetta, Wlodarski, Marcin W., Ramenghi, Ugo, Santoro, Claudio, Ellis, Steven R., Loreni, Fabrizio, Follenzi, Antonia, Dianzani, Irma
Publicado 2017

Author Correction: Lymphoblastoid cell lines from Diamond Blackfan anaemia patients exhibit a full ribosomal stress phenotype that is rescued by gene therapy

por Aspesi, Anna, Monteleone, Valentina, Betti, Marta, Actis, Chiara, Morleo, Giulia, Sculco, Marika, Guarrera, Simonetta, Wlodarski, Marcin W., Ramenghi, Ugo, Santoro, Claudio, Ellis, Steven R., Loreni, Fabrizio, Follenzi, Antonia, Dianzani, Irma
Publicado 2018

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds

por Carrella, Diego, Manni, Isabella, Tumaini, Barbara, Dattilo, Rosanna, Papaccio, Federica, Mutarelli, Margherita, Sirci, Francesco, Amoreo, Carla A., Mottolese, Marcella, Iezzi, Manuela, Ciolli, Laura, Aria, Valentina, Bosotti, Roberta, Isacchi, Antonella, Loreni, Fabrizio, Bardelli, Alberto, Avvedimento, Vittorio E., di Bernardo, Diego, Cardone, Luca
Publicado 2016

Mutation of the Diamond-Blackfan Anemia Gene Rps7 in Mouse Results in Morphological and Neuroanatomical Phenotypes

por Watkins-Chow, Dawn E., Cooke, Joanna, Pidsley, Ruth, Edwards, Andrew, Slotkin, Rebecca, Leeds, Karen E., Mullen, Raymond, Baxter, Laura L., Campbell, Thomas G., Salzer, Marion C., Biondini, Laura, Gibney, Gretchen, Phan Dinh Tuy, Françoise, Chelly, Jamel, Morris, H. Douglas, Riegler, Johannes, Lythgoe, Mark F., Arkell, Ruth M., Loreni, Fabrizio, Flint, Jonathan, Pavan, William J., Keays, David A.
Publicado 2013

Correction: Mutation of the Diamond-Blackfan Anemia Gene Rps7 in Mouse Results in Morphological and Neuroanatomical Phenotypes

por Watkins-Chow, Dawn E., Cooke, Joanna, Pidsley, Ruth, Edwards, Andrew, Slotkin, Rebecca, Leeds, Karen E., Mullen, Raymond, Baxter, Laura L., Campbell, Thomas G., Salzer, Marion C., Biondini, Laura, Gibney, Gretchen, Tuy, Françoise Phan Dinh, Chelly, Jamel, Morris, H. Douglas, Riegler, Johannes, Lythgoe, Mark F., Arkell, Ruth M., Loreni, Fabrizio, Flint, Jonathan, Pavan, William J., Keays, David A.
Publicado 2015