Homology Model and Docking-Based Virtual Screening for Ligands of Human Dyskerin as New Inhibitors of Telomerase for Cancer Treatment

por Armando, Romina Gabriela, Mengual Gómez, Diego Luis, Juritz, Ezequiel Ivan, Lorenzano Menna, Pablo, Gomez, Daniel Eduardo
Publicado 2018

Timing of Novel Drug 1A-116 to Circadian Rhythms Improves Therapeutic Effects against Glioblastoma

por Trebucq, Laura Lucía, Cardama, Georgina Alexandra, Lorenzano Menna, Pablo, Golombek, Diego Andrés, Chiesa, Juan José, Marpegan, Luciano
Publicado 2021

Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity

por González, Nazareno, Cardama, Georgina A., Chinestrad, Patricio, Robles-Valero, Javier, Rodríguez-Fdez, Sonia, Lorenzo-Martín, L. Francisco, Bustelo, Xosé R., Lorenzano Menna, Pablo, Gomez, Daniel E.
Publicado 2020

Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models

por Cardama, Georgina A., Maggio, Julian, Valdez Capuccino, Lucas, Gonzalez, Nazareno, Matiller, Valentina, Ortega, Hugo H., Perez, German R., Demarco, Ignacio A., Spitzer, Eduardo, Gomez, Daniel E., Lorenzano Menna, Pablo, Alonso, Daniel F.
Publicado 2022

VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma

por Lorenzo-Martín, L. Francisco, Fernández-Parejo, Natalia, Menacho-Márquez, Mauricio, Rodríguez-Fdez, Sonia, Robles-Valero, Javier, Zumalave, Sonia, Fabbiano, Salvatore, Pascual, Gloria, García-Pedrero, Juana M., Abad, Antonio, García-Macías, María C., González, Nazareno, Lorenzano-Menna, Pablo, Pavón, Miguel A., González-Sarmiento, Rogelio, Segrelles, Carmen, Paramio, Jesús M., Tubío, José M. C., Rodrigo, Juan P., Benitah, Salvador A., Cuadrado, Myriam, Bustelo, Xosé R.
Publicado 2020