Longitudinal clonal dynamics of HIV-1 latent reservoirs measured by combination quadruplex polymerase chain reaction and sequencing

por Cho, Alice, Gaebler, Christian, Olveira, Thiago, Ramos, Victor, Saad, Marwa, Lorenzi, Julio C. C., Gazumyan, Anna, Moir, Susan, Caskey, Marina, Chun, Tae-Wook, Nussenzweig, Michel C.
Publicado 2022

Combination of quadruplex qPCR and next-generation sequencing for qualitative and quantitative analysis of the HIV-1 latent reservoir

por Gaebler, Christian, Lorenzi, Julio C.C., Oliveira, Thiago Y., Nogueira, Lilian, Ramos, Victor, Lu, Ching-Lan, Pai, Joy A., Mendoza, Pilar, Jankovic, Mila, Caskey, Marina, Nussenzweig, Michel C.
Publicado 2019

Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation

por Cohn, Lillian B., da Silva, Israel T., Valieris, Renan, Huang, Amy S., Lorenzi, Julio C. C., Cohen, Yehuda Z., Pai, Joy A., Butler, Allison L., Caskey, Marina, Jankovic, Mila, Nussenzweig, Michel C.
Publicado 2018

Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Primary African Isolates

por Lorenzi, Julio C. C., Mendoza, Pilar, Cohen, Yehuda Z., Nogueira, Lilian, Lavine, Christy, Sapiente, Joseph, Wiatr, Marie, Mugo, Nelly R., Mujugira, Andrew, Delany, Sinead, Lingappa, Jairam, Celum, Connie, Seaman, Michael S., Caskey, Marina, Nussenzweig, Michel C.
Publicado 2021

Neutralizing Activity of Broadly Neutralizing Anti-HIV-1 Antibodies against Clade B Clinical Isolates Produced in Peripheral Blood Mononuclear Cells

por Cohen, Yehuda Z., Lorenzi, Julio C. C., Seaman, Michael S., Nogueira, Lilian, Schoofs, Till, Krassnig, Lisa, Butler, Allison, Millard, Katrina, Fitzsimons, Tomas, Daniell, Xiaoju, Dizon, Juan P., Shimeliovich, Irina, Montefiori, David C., Caskey, Marina, Nussenzweig, Michel C.
Publicado 2018

Relationship between intact HIV-1 proviruses in circulating CD4(+) T cells and rebound viruses emerging during treatment interruption

por Lu, Ching-Lan, Pai, Joy A., Nogueira, Lilian, Mendoza, Pilar, Gruell, Henning, Oliveira, Thiago Y., Barton, John, Lorenzi, Julio C. C., Cohen, Yehuda Z., Cohn, Lillian B., Klein, Florian, Caskey, Marina, Nussenzweig, Michel C., Jankovic, Mila
Publicado 2018

Longitudinal analysis of clinical serology assay performance and neutralising antibody levels in COVID19 convalescents

por Muecksch, Frauke, Wise, Helen, Batchelor, Becky, Squires, Maria, Semple, Elizabeth, Richardson, Claire, McGuire, Jacqueline, Clearly, Sarah, Furrie, Elizabeth, Neil, Greig, Hay, Gordon, Templeton, Kate, Lorenzi, Julio C.C., Hatziioannou, Theodora, Jenks, Sara, Bieniasz, Paul D.
Publicado 2020

Longitudinal Serological Analysis and Neutralizing Antibody Levels in Coronavirus Disease 2019 Convalescent Patients

por Muecksch, Frauke, Wise, Helen, Batchelor, Becky, Squires, Maria, Semple, Elizabeth, Richardson, Claire, McGuire, Jacqueline, Clearly, Sarah, Furrie, Elizabeth, Greig, Neil, Hay, Gordon, Templeton, Kate, Lorenzi, Julio C C, Hatziioannou, Theodora, Jenks, Sara, Bieniasz, Paul D
Publicado 2020

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

por Schäfer, Alexandra, Muecksch, Frauke, Lorenzi, Julio C. C., Leist, Sarah R., Cipolla, Melissa, Bournazos, Stylianos, Schmidt, Fabian, Gazumyan, Anna, Baric, Ralph S., Robbiani, Davide F., Hatziioannou, Theodora, Ravetch, Jeffrey V., Bieniasz, Paul D., Nussenzweig, Michel C., Sheahan, Timothy P.
Publicado 2020

Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo

por Schäfer, Alexandra, Muecksch, Frauke, Lorenzi, Julio C.C., Leist, Sarah R., Cipolla, Melissa, Bournazos, Stylianos, Schmidt, Fabian, Maison, Rachel M., Gazumyan, Anna, Martinez, David R., Baric, Ralph S., Robbiani, Davide F., Hatziioannou, Theodora, Ravetch, Jeffrey V., Bieniasz, Paul D., Bowen, Richard A., Nussenzweig, Michel C., Sheahan, Timothy P.
Publicado 2020

Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA

por Gaebler, Christian, Falcinelli, Shane D., Stoffel, Elina, Read, Jenna, Murtagh, Ross, Oliveira, Thiago Y., Ramos, Victor, Lorenzi, Julio C. C., Kirchherr, Jennifer, James, Katherine S., Allard, Brigitte, Baker, Caroline, Kuruc, JoAnn D., Caskey, Marina, Archin, Nancie M., Siliciano, Robert F., Margolis, David M., Nussenzweig, Michel C.
Publicado 2021

Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption

por Vibholm, Line K., Lorenzi, Julio C. C., Pai, Joy A., Cohen, Yehuda Z., Oliveira, Thiago Y., Barton, John P., Garcia Noceda, Marco, Lu, Ching-Lan, Ablanedo-Terrazas, Yuria, Del Rio Estrada, Perla M., Reyes-Teran, Gustavo, Tolstrup, Martin, Denton, Paul W., Damsgaard, Tine, Søgaard, Ole S., Nussenzweig, Michel C.
Publicado 2019

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

por Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Hoffmann, Hans-Heinrich, Michailidis, Eleftherios, Lorenzi, Julio C. C., Mendoza, Pilar, Rutkowska, Magdalena, Bednarski, Eva, Gaebler, Christian, Agudelo, Marianna, Cho, Alice, Wang, Zijun, Gazumyan, Anna, Cipolla, Melissa, Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D.
Publicado 2020

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

por Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Hoffmann, Hans-Heinrich, Michailidis, Eleftherios, Lorenzi, Julio C.C., Mendoza, Pilar, Rutkowska, Magdalena, Bednarski, Eva, Gaebler, Christian, Agudelo, Marianna, Cho, Alice, Wang, Zijun, Gazumyan, Anna, Cipolla, Melissa, Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D.
Publicado 2020

Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro

por Wang, Zijun, Lorenzi, Julio C. C., Muecksch, Frauke, Finkin, Shlomo, Viant, Charlotte, Gaebler, Christian, Cipolla, Melissa, Hoffman, Hans-Heinrich, Oliveira, Thiago Y., Oren, Deena A., Ramos, Victor, Nogueira, Lilian, Michailidis, Eleftherios, Robbiani, Davide F., Gazumyan, Anna, Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.
Publicado 2020

Enhanced SARS-CoV-2 neutralization by dimeric IgA

por Wang, Zijun, Lorenzi, Julio C. C., Muecksch, Frauke, Finkin, Shlomo, Viant, Charlotte, Gaebler, Christian, Cipolla, Melissa, Hoffman, Hans-Heinrich, Oliveira, Thiago Y., Oren, Deena A., Ramos, Victor, Nogueira, Lilian, Michailidis, Eleftherios, Robbiani, Davide F., Gazumyan, Anna, Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.
Publicado 2021

Relationship between latent and rebound viruses in a clinical trial of anti–HIV-1 antibody 3BNC117

por Cohen, Yehuda Z., Lorenzi, Julio C.C., Krassnig, Lisa, Barton, John P., Burke, Leah, Pai, Joy, Lu, Ching-Lan, Mendoza, Pilar, Oliveira, Thiago Y., Sleckman, Christopher, Millard, Katrina, Butler, Allison L., Dizon, Juan P., Belblidia, Shiraz A., Witmer-Pack, Maggi, Shimeliovich, Irina, Gulick, Roy M., Seaman, Michael S., Jankovic, Mila, Caskey, Marina, Nussenzweig, Michel C.
Publicado 2018

Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study

por Cohen, Yehuda Z., Butler, Allison L., Millard, Katrina, Witmer-Pack, Maggi, Levin, Rebeka, Unson-O’Brien, Cecilia, Patel, Roshni, Shimeliovich, Irina, Lorenzi, Julio C. C., Horowitz, Jill, Walsh, Stephen R., Lin, Shu, Weiner, Joshua A., Tse, Anna, Sato, Alicia, Bennett, Chelsey, Mayer, Bryan, Seaton, Kelly E., Yates, Nicole L., Baden, Lindsey R., deCamp, Allan C., Ackerman, Margaret E., Seaman, Michael S., Tomaras, Georgia D., Nussenzweig, Michel C., Caskey, Marina
Publicado 2019

Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies

por Muecksch, Frauke, Weisblum, Yiska, Barnes, Christopher O., Schmidt, Fabian, Schaefer-Babajew, Dennis, Lorenzi, Julio C C, Flyak, Andrew I, DeLaitsch, Andrew T, Huey-Tubman, Kathryn E, Hou, Shurong, Schiffer, Celia A., Gaebler, Christian, Wang, Zijun, Da Silva, Justin, Poston, Daniel, Finkin, Shlomo, Cho, Alice, Cipolla, Melissa, Oliveira, Thiago Y., Millard, Katrina G., Ramos, Victor, Gazumyan, Anna, Rutkowska, Magdalena, Caskey, Marina, Nussenzweig, Michel C., Bjorkman, Pamela J., Hatziioannou, Theodora, Bieniasz, Paul D.
Publicado 2021

Early treatment with a combination of two potent neutralizing antibodies improves clinical outcomes and reduces virus replication and lung inflammation in SARS-CoV-2 infected macaq...

por Van Rompay, Koen K. A., Olstad, Katherine J., Sammak, Rebecca L., Dutra, Joseph, Watanabe, Jennifer K., Usachenko, Jodie L., Immareddy, Ramya, Verma, Anil, Shaan Lakshmanappa, Yashavanth, Schmidt, Brian A., Roh, Jamin W., Elizaldi, Sonny R., Allen, A. Mark, Muecksch, Frauke, Lorenzi, Julio C. C., Lockwood, Sarah, Pollard, Rachel E., Yee, JoAnn L., Nham, Peter B., Ardeshir, Amir, Deere, Jesse D., Patterson, Jean, Dang, Que, Hatziioannou, Theodora, Bieniasz, Paul D., Iyer, Smita S., Hartigan-O’Connor, Dennis J., Nussenzweig, Michel C., Reader, J. Rachel
Publicado 2021