A curated census of autophagy-modulating proteins and small molecules: Candidate targets for cancer therapy

por Lorenzi, Philip L, Claerhout, Sofie, Mills, Gordon B, Weinstein, John N
Publicado 2014

An Artifact in LC-MS/MS Measurement of Glutamine and Glutamic Acid: In-Source Cyclization to Pyroglutamic Acid

por Purwaha, Preeti, Silva, Leslie P., Hawke, David H., Weinstein, John N., Lorenzi, Philip L.
Publicado 2014

Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cells

por Purwaha, Preeti, Lorenzi, Philip L., Silva, Leslie P., Hawke, David H., Weinstein, John N.
Publicado 2014

EWS‐FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine‐glycine biosynthesis

por Sen, Nirmalya, Cross, Allison M., Lorenzi, Philip L., Khan, Javed, Gryder, Berkley E., Kim, Suntae, Caplen, Natasha J.
Publicado 2018

ElemCor: accurate data analysis and enrichment calculation for high-resolution LC-MS stable isotope labeling experiments

por Du, Di, Tan, Lin, Wang, Yumeng, Peng, Bo, Weinstein, John N., Wondisford, Fredric E., Su, Xiaoyang, Lorenzi, Philip L.
Publicado 2019

The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling

por Yan, Hannah, Walker, Forrest C., Ali, Arushana, Han, Hyojeong, Tan, Lin, Veillon, Lucas, Lorenzi, Philip L., Baldridge, Megan T., King, Katherine Y.
Publicado 2022

Assessment of l-Asparaginase Pharmacodynamics in Mouse Models of Cancer

por Horvath, Thomas D., Chan, Wai Kin, Pontikos, Michael A., Martin, Leona A., Du, Di, Tan, Lin, Konopleva, Marina, Weinstein, John N., Lorenzi, Philip L.
Publicado 2019

Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and re-sensitizes acute myeloid leukemia to BCL-2 inhibition

por Carter, Bing Z., Mak, Po Yee, Tao, Wenjing, Warmoes, Marc, Lorenzi, Philip L., Mak, Duncan, Ruvolo, Vivian, Tan, Lin, Cidado, Justin, Drew, Lisa, Andreeff, Michael
Publicado 2020

Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy

por Li, Gang, Li, Xin, Mahmud, Iqbal, Ysaguirre, Jazmin, Fekry, Baharan, Wang, Shuyue, Wei, Bo, Eckel-Mahan, Kristin L., Lorenzi, Philip L., Lehner, Richard, Sun, Kai
Publicado 2023

The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease

por Li, Li, Long, Jianyin, Mise, Koki, Poungavrin, Naravat, Lorenzi, Philip L., Mahmud, Iqbal, Tan, Lin, Saha, Pradip K., Kanwar, Yashpal S., Chang, Benny H., Danesh, Farhad R.
Publicado 2023

Regulation of growth, invasion and metabolism of breast ductal carcinoma through CCL2/CCR2 signaling interactions with MET receptor tyrosine kinases

por Acevedo, Diana Sofía, Fang, Wei Bin, Rao, Vinamratha, Penmetcha, Vedha, Leyva, Hannah, Acosta, Gabriela, Cote, Paige, Brodine, Rebecca, Swerdlow, Russell, Tan, Lin, Lorenzi, Philip L, Cheng, Nikki
Publicado 2022

Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas

por de Groot, Evelyn, Varghese, Sruthy, Tan, Lin, Knighton, Barbara, Sobieski, Mary, Nguyen, Nghi, Park, Yong Sung, Powell, Reid, Lorenzi, Philip L., Zheng, Bin, Stephan, Clifford, Gopal, Y. N. Vashisht
Publicado 2022

Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway

por Dai, Bingbing, Augustine, Jithesh J., Kang, Ya’an, Roife, David, Li, Xinqun, Deng, Jenying, Tan, Lin, Rusling, Leona A., Weinstein, John N., Lorenzi, Philip L., Kim, Michael P., Fleming, Jason B.
Publicado 2021

Adipose tissue–specific ablation of Ces1d causes metabolic dysregulation in mice

por Li, Gang, Li, Xin, Yang, Li, Wang, Shuyue, Dai, Yulin, Fekry, Baharan, Veillon, Lucas, Tan, Lin, Berdeaux, Rebecca, Eckel-Mahan, Kristin, Lorenzi, Philip L, Zhao, Zhongming, Lehner, Richard, Sun, Kai
Publicado 2022

Multiplexing siRNAs to compress RNAi-based screen size in human cells

por Martin, Scott E., Jones, Tamara L., Thomas, Cheryl L., Lorenzi, Philip L., Nguyen, Dac A., Runfola, Timothy, Gunsior, Michele, Weinstein, John N., Goldsmith, Paul K., Lader, Eric, Huppi, Konrad, Caplen, Natasha J.
Publicado 2007

Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression

por Grima-Reyes, Manuel, Vandenberghe, Ashaina, Nemazanyy, Ivan, Meola, Pauline, Paul, Rachel, Reverso-Meinietti, Julie, Martinez-Turtos, Adriana, Nottet, Nicolas, Chan, Wai-Kin, Lorenzi, Philip L., Marchetti, Sandrine, Ricci, Jean-Ehrland, Chiche, Johanna
Publicado 2022

Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial metabolic reprogramming

por Wang, Yongxing, Kulkarni, Vikram V., Pantaleón García, Jezreel, Leiva-Juárez, Miguel M., Goldblatt, David L., Gulraiz, Fahad, Chen, Jichao, Donepudi, Sri Ramya, Lorenzi, Philip L., Wang, Hao, Wong, Lee-Jun, Tuvim, Michael J., Evans, Scott E.
Publicado 2023

Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer

por Wall, Steven W., Sanchez, Lilia, Tuttle, Kelly Scribner, Pearson, Scott J., Soma, Shivatheja, Wyatt, Garhett L., Carter, Hannah N., Jenschke, Ramsey M., Tan, Lin, Martinez, Sara A., Lorenzi, Philip L., Gohil, Vishal M., Rijnkels, Monique, Porter, Weston W.
Publicado 2023

Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes

por Finnicum, Casey T., Rahal, Zahraa, Hassane, Maya, Treekitkarnmongkol, Warapen, Sinjab, Ansam, Morris, Rhiannon, Liu, Yuejiang, Tang, Elizabeth L., Viet, Sarah, Petersen, Jason L., Lorenzi, Philip L., Tan, Lin, Petrosino, Joseph, Hoffman, Kristi L., Fujimoto, Junya, Moghaddam, Seyed Javad, Kadara, Humam
Publicado 2022

Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer

por Cargill, Kasey R., Stewart, C. Allison, Park, Elizabeth M., Ramkumar, Kavya, Gay, Carl M., Cardnell, Robert J., Wang, Qi, Diao, Lixia, Shen, Li, Fan, You-Hong, Chan, Wai Kin, Lorenzi, Philip L., Oliver, Trudy G., Wang, Jing, Byers, Lauren A.
Publicado 2021