Interactions of Spike-RBD of SARS-CoV-2 and Platelet Factor 4: New Insights in the Etiopathogenesis of Thrombosis

por Passariello, Margherita, Vetrei, Cinzia, Amato, Felice, De Lorenzo, Claudia
Publicado 2021

Novel Human Bispecific Aptamer–Antibody Conjugates for Efficient Cancer Cell Killing

por Passariello, Margherita, Camorani, Simona, Vetrei, Cinzia, Cerchia, Laura, De Lorenzo, Claudia
Publicado 2019

Ipilimumab and Its Derived EGFR Aptamer-Based Conjugate Induce Efficient NK Cell Activation against Cancer Cells

por Passariello, Margherita, Camorani, Simona, Vetrei, Cinzia, Ricci, Stefania, Cerchia, Laura, De Lorenzo, Claudia
Publicado 2020

A Comparison of the Antitumor Efficacy of Novel Multi-Specific Tribodies with Combinations of Approved Immunomodulatory Antibodies

por Manna, Lorenzo, Rapuano Lembo, Rosa, Yoshioka, Asami, Nakamura, Koji, Passariello, Margherita, De Lorenzo, Claudia
Publicado 2023

Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments

por Vetrei, Cinzia, Passariello, Margherita, Froechlich, Guendalina, Rapuano Lembo, Rosa, Zambrano, Nicola, De Lorenzo, Claudia
Publicado 2021

New Insights on the Role of Anti-PD-L1 and Anti-CTLA-4 mAbs on Different Lymphocytes Subpopulations in TNBC

por Lembo, Rosa Rapuano, Manna, Lorenzo, Froechlich, Guendalina, Sasso, Emanuele, Passariello, Margherita, De Lorenzo, Claudia
Publicado 2022

Cardiotoxic effects of the novel approved anti-ErbB2 agents and reverse cardioprotective effects of ranolazine

por De Lorenzo, Claudia, Paciello, Rolando, Riccio, Gennaro, Rea, Domenica, Barbieri, Antonio, Coppola, Carmela, Maurea, Nicola
Publicado 2018

Novel Combinations of Human Immunomodulatory mAbs Lacking Cardiotoxic Effects for Therapy of TNBC

por Vetrei, Cinzia, Passariello, Margherita, Froechlich, Guendalina, Rapuano Lembo, Rosa, Sasso, Emanuele, Zambrano, Nicola, De Lorenzo, Claudia
Publicado 2021

Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo

por Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Inoue, Toshikazu, Nakamura, Koji, De Lorenzo, Claudia
Publicado 2022

Trastuzumab and target-therapy side effects: Is still valid to differentiate anthracycline Type I from Type II cardiomyopathies?

por Riccio, Gennaro, Coppola, Carmela, Piscopo, Giovanna, Capasso, Immacolata, Maurea, Carlo, Esposito, Emanuela, De Lorenzo, Claudia, Maurea, Nicola
Publicado 2016

A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells

por Sasso, Emanuele, Latino, Debora, Froechlich, Guendalina, Succoio, Mariangela, Passariello, Margherita, De Lorenzo, Claudia, Nicosia, Alfredo, Zambrano, Nicola
Publicado 2018

Comparative Analysis of a Human Neutralizing mAb Specific for SARS-CoV-2 Spike-RBD with Cilgavimab and Tixagevimab for the Efficacy on the Omicron Variant in Neutralizing and Detec...

por Passariello, Margherita, Esposito, Speranza, Manna, Lorenzo, Rapuano Lembo, Rosa, Zollo, Immacolata, Sasso, Emanuele, Amato, Felice, De Lorenzo, Claudia
Publicado 2023

High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand

por Zambrano, Nicola, Froechlich, Guendalina, Lazarevic, Dejan, Passariello, Margherita, Nicosia, Alfredo, De Lorenzo, Claudia, Morelli, Marco J., Sasso, Emanuele
Publicado 2022

Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling

por Passariello, Margherita, D’Alise, Anna Morena, Esposito, Annachiara, Vetrei, Cinzia, Froechlich, Guendalina, Scarselli, Elisa, Nicosia, Alfredo, De Lorenzo, Claudia
Publicado 2019

Novel Bi-Specific Immuno-Modulatory Tribodies Potentiate T Cell Activation and Increase Anti-Tumor Efficacy

por Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Rapuano Lembo, Rosa, Manna, Lorenzo, Nakamura, Koji, De Lorenzo, Claudia
Publicado 2022

One-Step Recovery of scFv Clones from High-Throughput Sequencing-Based Screening of Phage Display Libraries Challenged to Cells Expressing Native Claudin-1

por Sasso, Emanuele, Paciello, Rolando, D'Auria, Francesco, Riccio, Gennaro, Froechlich, Guendalina, Cortese, Riccardo, Nicosia, Alfredo, De Lorenzo, Claudia, Zambrano, Nicola
Publicado 2015

A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy

por D'Avino, Chiara, Palmieri, Dario, Braddom, Ashley, Zanesi, Nicola, James, Cindy, Cole, Sara, Salvatore, Francesco, Croce, Carlo M., De Lorenzo, Claudia
Publicado 2016

Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models

por Quagliariello, Vincenzo, Passariello, Margherita, Rea, Domenica, Barbieri, Antonio, Iovine, Martina, Bonelli, Annamaria, Caronna, Antonietta, Botti, Gerardo, De Lorenzo, Claudia, Maurea, Nicola
Publicado 2020

Antineoplastic-related cardiotoxicity, morphofunctional aspects in a murine model: contribution of the new tool 2D-speckle tracking

por Coppola, Carmela, Riccio, Gennaro, Barbieri, Antonio, Monti, Maria Gaia, Piscopo, Giovanna, Rea, Domenica, Arra, Claudio, Maurea, Carlo, De Lorenzo, Claudia, Maurea, Nicola
Publicado 2016

A Novel Human Neutralizing mAb Recognizes Delta, Gamma and Omicron Variants of SARS-CoV-2 and Can Be Used in Combination with Sotrovimab

por Passariello, Margherita, Ferrucci, Veronica, Sasso, Emanuele, Manna, Lorenzo, Lembo, Rosa Rapuano, Pascarella, Stefano, Fusco, Giovanna, Zambrano, Nicola, Zollo, Massimo, De Lorenzo, Claudia
Publicado 2022