Challenges in studying geographic atrophy (GA) age-related macular degeneration: the potential of a new mouse model with GA-like features

por Ratnayaka, J. Arjuna, Lotery, Andrew J.
Publicado 2019

Beyond the Complement Cascade: Insights into Systemic Immunosenescence and Inflammaging in Age-Related Macular Degeneration and Current Barriers to Treatment

por Khan, Adnan H., Chowers, Itay, Lotery, Andrew J.
Publicado 2023

The disparity between funding for eye research vs. the high cost of sight-loss in the UK

por Dewing, Jennifer M., Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2022

Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

por Keeling, Eloise, Lotery, Andrew J., Tumbarello, David A., Ratnayaka, J. Arjuna
Publicado 2018

Complement factor I and age-related macular degeneration

por Alexander, Philip, Gibson, Jane, Cree, Angela J., Ennis, Sarah, Lotery, Andrew J.
Publicado 2014

The Diverse Roles of TIMP-3: Insights into Degenerative Diseases of the Senescent Retina and Brain

por Dewing, Jennifer M., Carare, Roxana O., Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2019

Macular thickness varies with age-related macular degeneration genetic risk variants in the UK Biobank cohort

por Kaye, Rebecca A., Patasova, Karina, Patel, Praveen J., Hysi, Pirro, Lotery, Andrew J.
Publicado 2021

Rare complement factor I variants associated with reduced macular thickness and age-related macular degeneration in the UK Biobank

por Tzoumas, Nikolaos, Kavanagh, David, Cordell, Heather J, Lotery, Andrew J, Patel, Praveen J, Steel, David H
Publicado 2022

Treatment Satisfaction and Well-Being in Patients with Myopic Choroidal Neovascularization Treated with Ranibizumab in the REPAIR Study

por Amoaku, Winfried M., Gale, Richard P., Lotery, Andrew J., Menon, Geeta, Sivaprasad, Sobha, Petrillo, Jennifer, Quinn, Jennifer
Publicado 2015

The complexities underlying age-related macular degeneration: could amyloid beta play an important role?

por Lynn, Savannah A., Keeling, Eloise, Munday, Rosie, Gabha, Gagandeep, Griffiths, Helen, Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2017

Multimodal Imaging in the Management of Choroidal Neovascularization Secondary to Central Serous Chorioretinopathy

por Hagag, Ahmed M., Chandra, Shruti, Khalid, Hagar, Lamin, Ali, Keane, Pearse A., Lotery, Andrew J., Sivaprasad, Sobha
Publicado 2020

Characterization of rabbit myocilin: Implications for human myocilin glycosylation and signal peptide usage

por Shepard, Allan R, Jacobson, Nasreen, Sui, Ruifang, Steely, H Thomas, Lotery, Andrew J, Stone, Edwin M, Clark, Abbot F
Publicado 2003

Serum Vascular Endothelial Growth Factor Levels in the IVAN Trial; Relationships with Drug, Dosing, and Systemic Serious Adverse Events

por Rogers, Chris A., Scott, Lauren J., Reeves, Barnaby C., Downes, Susan, Lotery, Andrew J., Dick, Andrew D., Chakravarthy, Usha
Publicado 2018

An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy

por Keeling, Eloise, Culling, Annabelle J., Johnston, David A., Chatelet, David S., Page, Anton, Tumbarello, David A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Publicado 2020

The effect of systemic levels of TNF-alpha and complement pathway activity on outcomes of VEGF inhibition in neovascular AMD

por Khan, Adnan H., Pierce, Charles O., De Salvo, Gabriella, Griffiths, Helen, Nelson, Marie, Cree, Angela J., Menon, Geeta, Lotery, Andrew J.
Publicado 2021

Aflibercept treatment for neovascular AMD beyond the first year: consensus recommendations by a UK expert roundtable panel, 2017 update

por Patel, Praveen J, Devonport, Helen, Sivaprasad, Sobha, Ross, Adam H, Walters, Gavin, Gale, Richard P, Lotery, Andrew J, Mahmood, Sajjad, Talks, James S, Napier, Jackie
Publicado 2017

A novel, wearable, electronic visual aid to assist those with reduced peripheral vision

por Brown, Ffion E., Sutton, Janice, Yuen, Ho M., Green, Dylan, Van Dorn, Spencer, Braun, Terry, Cree, Angela J., Russell, Stephen R., Lotery, Andrew J.
Publicado 2019

Rare Genetic Variants in Complement Factor I Lead to Low FI Plasma Levels Resulting in Increased Risk of Age-Related Macular Degeneration

por Hallam, Thomas M., Marchbank, Kevin J., Harris, Claire L., Osmond, Clive, Shuttleworth, Victoria G., Griffiths, Helen, Cree, Angela J., Kavanagh, David, Lotery, Andrew J.
Publicado 2020

Characterization of the Frmd7 Knock-Out Mice Generated by the EUCOMM/COMP Repository as a Model for Idiopathic Infantile Nystagmus (IIN)

por Salman, Ahmed, Hutton, Samuel B., Newall, Tutte, Scott, Jennifer A., Griffiths, Helen L., Lee, Helena, Gomez-Nicola, Diego, Lotery, Andrew J., Self, Jay E.
Publicado 2020

A laser-induced mouse model of progressive retinal degeneration with central sparing displays features of parafoveal geographic atrophy

por Khan, Adnan H., Soundara Pandi, Sudha Priya, Scott, Jennifer A., Sánchez-Bretaño, Aida, Lynn, Savannah A., Ratnayaka, J. Arjuna, Teeling, Jessica L., Lotery, Andrew J.
Publicado 2023