Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood–Brain Barrier and Its Implementation into Compound Optimization in Drug Discovery

por Cui, Yunhai, Lotz, Ralf, Rapp, Hermann, Klinder, Klaus, Himstedt, Anneke, Sauer, Achim
Publicado 2019

Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib

por Wind, Sven, Schmid, Ulrike, Freiwald, Matthias, Marzin, Kristell, Lotz, Ralf, Ebner, Thomas, Stopfer, Peter, Dallinger, Claudia
Publicado 2019

Cell-to-Medium Concentration Ratio Overshoot in the Uptake of Statins by Human Hepatocytes in Suspension, but Not in Monolayer: Kinetic Analysis Suggesting a Partial Loss of Functi...

por Lee, Wooin, Koyama, Satoshi, Morita, Kiyoe, Kiriake, Aya, Kikuchi, Ryota, Chu, Xiaoyan, Lee, Nora, Scialis, Renato J., Shen, Hong, Kimoto, Emi, Tremaine, Larry, Ishiguro, Naoki, Lotz, Ralf, Maeda, Kazuya, Kusuhara, Hiroyuki, Sugiyama, Yuichi
Publicado 2020