Rational Redesign of a Functional Protein Kinase-Substrate Interaction

por Chen, Catherine, Nimlamool, Wutigri, Miller, Chad J., Lou, Hua Jane, Turk, Benjamin E.
Publicado 2017

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

por Cho, Eunice, Lou, Hua Jane, Kuruvilla, Leena, Calderwood, David A., Turk, Benjamin E.
Publicado 2021

Oxyresveratrol Inhibits IL-1β-Induced Inflammation via Suppressing AKT and ERK1/2 Activation in Human Microglia, HMC3

por Hankittichai, Phateep, Lou, Hua Jane, Wikan, Nitwara, Smith, Duncan R., Potikanond, Saranyapin, Nimlamool, Wutigri
Publicado 2020

Biochemical characterization of FIKK8 – A unique protein kinase from the malaria parasite Plasmodium falciparum and other apicomplexans

por Osman, Khan T., Lou, Hua Jane, Qiu, Wei, Brand, Verena, Edwards, Aled M., Turk, Benjamin E., Hui, Raymond
Publicado 2015

Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry

por Simon, Bertrand, Lou, Hua Jane, Huet-Calderwood, Clotilde, Shi, Guangda, Boggon, Titus J., Turk, Benjamin E., Calderwood, David A.
Publicado 2022

Unmasking Determinants of Specificity in the Human Kinome

por Creixell, Pau, Palmeri, Antonio, Miller, Chad J., Lou, Hua Jane, Santini, Cristina C., Nielsen, Morten, Turk, Benjamin E., Linding, Rune
Publicado 2015

Substrate and Inhibitor Specificity of the Type II p21-Activated Kinase, PAK6

por Gao, Jia, Ha, Byung Hak, Lou, Hua Jane, Morse, Elizabeth M., Zhang, Rong, Calderwood, David A., Turk, Benjamin E., Boggon, Titus J.
Publicado 2013

Identification of PNG kinase substrates uncovers interactions with the translational repressor TRAL in the oocyte-to-embryo transition

por Hara, Masatoshi, Lourido, Sebastian, Petrova, Boryana, Lou, Hua Jane, Von Stetina, Jessica R, Kashevsky, Helena, Turk, Benjamin E, Orr-Weaver, Terry L
Publicado 2018

Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

por Shehata, Saifeldin N., Hunter, Roger W., Ohta, Eriko, Peggie, Mark W., Lou, Hua Jane, Sicheri, Frank, Zeqiraj, Elton, Turk, Benjamin E., Sakamoto, Kei
Publicado 2012

Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity

por Howard, Conor J, Hanson-Smith, Victor, Kennedy, Kristopher J, Miller, Chad J, Lou, Hua Jane, Johnson, Alexander D, Turk, Benjamin E, Holt, Liam J
Publicado 2014

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop

por Cobbaut, Mathias, Derua, Rita, Döppler, Heike, Lou, Hua Jane, Vandoninck, Sandy, Storz, Peter, Turk, Benjamin E., Seufferlein, Thomas, Waelkens, Etienne, Janssens, Veerle, Van Lint, Johan
Publicado 2017

Ancestral reconstruction reveals mechanisms of ERK regulatory evolution

por Sang, Dajun, Pinglay, Sudarshan, Wiewiora, Rafal P, Selvan, Myvizhi E, Lou, Hua Jane, Chodera, John D, Turk, Benjamin E, Gümüş, Zeynep H, Holt, Liam J
Publicado 2019

Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail

por Sexton, Joel A., Potchernikov, Tony, Bibeau, Jeffrey P., Casanova-Sepúlveda, Gabriela, Cao, Wenxiang, Lou, Hua Jane, Boggon, Titus J., De La Cruz, Enrique M., Turk, Benjamin E.
Publicado 2023

Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

por Miller, Chad J., Lou, Hua Jane, Simpson, Craig, van de Kooij, Bert, Ha, Byung Hak, Fisher, Oriana S., Pirman, Natasha L., Boggon, Titus J., Rinehart, Jesse, Yaffe, Michael B., Linding, Rune, Turk, Benjamin E.
Publicado 2019

Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

por Chen, Catherine, Ha, Byung Hak, Thévenin, Anastasia F., Lou, Hua Jane, Zhang, Rong, Yip, Kevin Y., Peterson, Jeffrey R., Gerstein, Mark, Kim, Philip M., Filippakopoulos, Panagis, Knapp, Stefan, Boggon, Titus J., Turk, Benjamin E.
Publicado 2014

A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding

por Terekhov, Stanislav S., Mokrushina, Yuliana A., Nazarov, Anton S., Zlobin, Alexander, Zalevsky, Arthur, Bourenkov, Gleb, Golovin, Andrey, Belogurov, Alexey, Osterman, Ilya A., Kulikova, Alexandra A., Mitkevich, Vladimir A., Lou, Hua Jane, Turk, Benjamin E., Wilmanns, Matthias, Smirnov, Ivan V., Altman, Sidney, Gabibov, Alexander G.
Publicado 2020

Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling

por Creixell, Pau, Schoof, Erwin M., Simpson, Craig D., Longden, James, Miller, Chad J., Lou, Hua Jane, Perryman, Lara, Cox, Thomas R., Zivanovic, Nevena, Palmeri, Antonio, Wesolowska-Andersen, Agata, Helmer-Citterich, Manuela, Ferkinghoff-Borg, Jesper, Itamochi, Hiroaki, Bodenmiller, Bernd, Erler, Janine T., Turk, Benjamin E., Linding, Rune
Publicado 2015