Allele Compensation in Tip60(+/−) Mice Rescues White Adipose Tissue Function In Vivo

por Gao, Yuan, Hamers, Nicole, Rakhshandehroo, Maryam, Berger, Ruud, Lough, John, Kalkhoven, Eric
Publicado 2014

Single-cell transcriptomic profiling reveals specific maturation signatures in human cardiomyocytes derived from LMNB2-inactivated induced pluripotent stem cells

por Wang, Jie, Morgan, William, Saini, Ankur, Liu, Tao, Lough, John, Han, Lu
Publicado 2022

Trichloroethylene Exposure during Cardiac Valvuloseptal Morphogenesis Alters Cushion Formation and Cardiac Hemodynamics in the Avian Embryo

por Drake, Victoria J., Koprowski, Stacy L., Lough, John, Hu, Norman, Smith, Susan M.
Publicado 2006

Myh6-driven Cre recombinase activates the DNA damage response and the cell cycle in the myocardium in the absence of loxP sites

por Wang, Xinrui, Lauth, Amelia, Wan, Tina C., Lough, John W., Auchampach, John A.
Publicado 2020

Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality

por Fisher, Joseph B., Horst, Audrey, Wan, Tina, Kim, Min-Su, Auchampach, John, Lough, John
Publicado 2016

Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model

por Gehrking, Kristin M., Andresen, J. Michael, Duvick, Lisa, Lough, John, Zoghbi, Huda Y., Orr, Harry T.
Publicado 2011

A Systematic Review of Ebstein’s Anomaly with Left Ventricular Noncompaction

por Thareja, Suma K., Frommelt, Michele A., Lincoln, Joy, Lough, John W., Mitchell, Michael E., Tomita-Mitchell, Aoy
Publicado 2022

Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors

por Si-Tayeb, Karim, Noto, Fallon K, Sepac, Ana, Sedlic, Filip, Bosnjak, Zeljko J, Lough, John W, Duncan, Stephen A
Publicado 2010

Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury

por Wang, Xinrui, Wan, Tina C., Kulik, Katherine R., Lauth, Amelia, Smith, Brian C., Lough, John W., Auchampach, John A.
Publicado 2022

Activin-A and Bmp4 Levels Modulate Cell Type Specification during CHIR-Induced Cardiomyogenesis

por Kim, Min-Su, Horst, Audrey, Blinka, Steven, Stamm, Karl, Mahnke, Donna, Schuman, James, Gundry, Rebekah, Tomita-Mitchell, Aoy, Lough, John
Publicado 2015

Significance of α-Myosin Heavy Chain (MYH6) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases

por Anfinson, Melissa, Fitts, Robert H., Lough, John W., James, Jeanne M., Simpson, Pippa M., Handler, Stephanie S., Mitchell, Michael E., Tomita-Mitchell, Aoy
Publicado 2022

Stress-Induced Cell-Cycle Activation in Tip60 Haploinsufficient Adult Cardiomyocytes

por Fisher, Joseph B., Kim, Min-Su, Blinka, Steven, Ge, Zhi-Dong, Wan, Tina, Duris, Christine, Christian, Desirae, Twaroski, Kirk, North, Paula, Auchampach, John, Lough, John
Publicado 2012

Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome

por Kim, Min-Su, Fleres, Brandon, Lovett, Jerrell, Anfinson, Melissa, Samudrala, Sai Suma K., Kelly, Lauren J., Teigen, Laura E., Cavanaugh, Matthew, Marquez, Maribel, Geurts, Aron M., Lough, John W., Mitchell, Michael E., Fitts, Robert H., Tomita-Mitchell, Aoy
Publicado 2020

371 Decreased Contraction Rate, Altered Calcium Transients, and Increased Proliferation seen in Patient-specific iPSC-CMs Modeling Ebsteins Anomaly and Left Ventricular Noncompacti...

por Samudrala, Sai Suma, Anfinson, Melissa, Cavanaugh, Matthew, Kim, Min-Su, Lamberton, Peter, Radandt, Jackson, Brown, Ryan, Liang, Huan Ling, Stamm, Karl, Zeeshan, Afzal, Strande, Jennifer, Frommelt, Michele, Lough, John W., Fitts, Robert, Mitchell, Michael E., Tomita-Mitchel, Aoy
Publicado 2022

Impact of MYH6 variants in hypoplastic left heart syndrome

por Tomita-Mitchell, Aoy, Stamm, Karl D., Mahnke, Donna K., Kim, Min-Su, Hidestrand, Pip M., Liang, Huan Ling, Goetsch, Mary A., Hidestrand, Mats, Simpson, Pippa, Pelech, Andrew N., Tweddell, James S., Benson, D. Woodrow, Lough, John W., Mitchell, Michael E.
Publicado 2016

Collagen‐Specific HSP47 (+) Myofibroblasts and CD163 (+) Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS‐CoV‐2 Infections

por Puzyrenko, Andrii, Jacobs, Elizabeth R., Padilla, Nathan, Devine, Adam, Aljadah, Michael, Gantner, Benjamin N., Pan, Amy Y., Lai, Shuping, Dai, Qiang, Rubenstein, Jason C., North, Paula E., Simpson, Pippa M., Willoughby, Rodney E., O'Meara, Caitlin C., Flinn, Michael A., Lough, John W., Ibrahim, El‐Sayed H., Zheng, Ze, Sun, Yunguang, Felix, Juan, Hunt, Bryan C., Ross, Gracious, Rui, Hallgeir, Benjamin, Ivor J.
Publicado 2023