High Levels of EBV-Encoded RNA 1 (EBER1) Trigger Interferon and Inflammation-Related Genes in Keratinocytes Expressing HPV16 E6/E7

por Aromseree, Sirinart, Middeldorp, Jaap M., Pientong, Chamsai, van Eijndhoven, Monique, Ramayanti, Octavia, Lougheed, Sinéad M., Pegtel, D. Michiel, Steenbergen, Renske D. M., Ekalaksananan, Tipaya
Publicado 2017

A Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion

por Michielon, Elisabetta, López González, Marta, Stolk, Dorian A., Stolwijk, Joeke G. C., Roffel, Sanne, Waaijman, Taco, Lougheed, Sinéad M., de Gruijl, Tanja D., Gibbs, Susan
Publicado 2023

The effect of everolimus and low-dose cyclophosphamide on immune cell subsets in patients with metastatic renal cell carcinoma: results from a phase I clinical trial

por Huijts, Charlotte M., Lougheed, Sinéad M., Bodalal, Zuhir, van Herpen, Carla M., Hamberg, Paul, Tascilar, Metin, Haanen, John B., Verheul, Henk M., de Gruijl, Tanja D., van der Vliet, Hans J.
Publicado 2019

Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition

por Oosterhoff, Dinja, Lougheed, Sinéad, van de Ven, Rieneke, Lindenberg, Jelle, van Cruijsen, Hester, Hiddingh, Lotte, Kroon, Jan, van den Eertwegh, Alfons J.M., Hangalapura, Basav, Scheper, Rik J., de Gruijl, Tanja D.
Publicado 2012

Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab

por Santegoets, Saskia JAM, Stam, Anita GM, Lougheed, Sinéad M, Gall, Helen, Jooss, Karin, Sacks, Natalie, Hege, Kristen, Lowy, Israel, Scheper, Rik J, Gerritsen, Winald R, van den Eertwegh, Alfons JM, de Gruijl, Tanja D
Publicado 2014

Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma

por Huijts, Charlotte M., Werter, Inge M., Lougheed, Sinéad M., Goedegebuure, Ruben S., van Herpen, Carla M., Hamberg, Paul, Tascilar, Metin, Haanen, John B., Verheul, Henk M., de Gruijl, Tanja D., van der Vliet, Hans J.
Publicado 2018

Functional characterization of a STAT3-dependent dendritic cell-derived CD14(+) cell population arising upon IL-10-driven maturation

por Lindenberg, Jelle J., van de Ven, Rieneke, Lougheed, Sinéad M., Zomer, Anoek, Santegoets, Saskia J.A.M., Griffioen, Arjan W., Hooijberg, Erik, van den Eertwegh, Alfons J.M., Thijssen, Victor L., Scheper, Rik J., Oosterhoff, Dinja, de Gruijl, Tanja D.
Publicado 2013

TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients

por Zom, Gijs G., Welters, Marij J.P., Loof, Nikki M., Goedemans, Renske, Lougheed, Sinéad, Valentijn, Rob R.P.M., Zandvliet, Maarten L., Meeuwenoord, Nico J., Melief, Cornelis J.M., de Gruijl, Tanja D., Van der Marel, Gijsbert A., Filippov, Dmitri V., Ossendorp, Ferry, Van der Burg, Sjoerd H.
Publicado 2016

IL-10 Conditioning of Human Skin Affects the Distribution of Migratory Dendritic Cell Subsets and Functional T Cell Differentiation

por Lindenberg, Jelle J., Oosterhoff, Dinja, Sombroek, Claudia C., Lougheed, Sinéad M., Hooijberg, Erik, Stam, Anita G. M., Santegoets, Saskia J. A. M., Tijssen, Henk J., Buter, Jan, Pinedo, Herbert M., van den Eertwegh, Alfons J. M., Scheper, Rik J., Koenen, Hans J. P. M., van de Ven, Rieneke, de Gruijl, Tanja D.
Publicado 2013

Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibition

por van den Ende, Tom, Ezdoglian, Aiarpi, Baas, Lisanne M., Bakker, Joyce, Lougheed, Sinéad M., Harrasser, Micaela, Waasdorp, Cynthia, van Berge Henegouwen, Mark I., Hulshof, Maarten C.C.M., Haj Mohammad, Nadia, van Hillegersberg, Richard, Mook, Stella, van der Laken, Conny J., van Grieken, Nicole C.T., Derks, Sarah, Bijlsma, Maarten F., van Laarhoven, Hanneke W.M., de Gruijl, Tanja D.
Publicado 2023

Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour-mediated immune suppression

por López González, Marta, Oosterhoff, Dinja, Lindenberg, Jelle J., Milenova, Ioanna, Lougheed, Sinead M., Martiáñez, Tania, Dekker, Henk, Quixabeira, Dafne Carolina Alves, Hangalapura, Basav, Joore, Jos, Piersma, Sander R., Cervera-Carrascon, Victor, Santos, Joao Manuel, Scheper, Rik J., Verheul, Henk M.W., Jiménez, Connie R., Van De Ven, Rieneke, Hemminki, Akseli, Van Beusechem, Victor W., De Gruijl, Tanja D.
Publicado 2019

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells

por Glykofridis, Iris E, Knol, Jaco C, Balk, Jesper A, Westland, Denise, Pham, Thang V, Piersma, Sander R, Lougheed, Sinéad M, Derakhshan, Sepide, Veen, Puck, Rooimans, Martin A, van Mil, Saskia E, Böttger, Franziska, Poddighe, Pino J, van de Beek, Irma, Drost, Jarno, Zwartkruis, Fried JT, de Menezes, Renee X, Meijers-Heijboer, Hanne EJ, Houweling, Arjan C, Jimenez, Connie R, Wolthuis, Rob MF
Publicado 2021