Lipopolysaccharide Stimulates p62-Dependent Autophagy-Like Aggregate Clearance in Hepatocytes

por Chen, Christine, Deng, Meihong, Sun, Qian, Loughran, Patricia, Billiar, Timothy R., Scott, Melanie J.
Publicado 2014

Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis

por Tyagi, Pradeep, Tyagi, Vikas, Yoshimura, Naoki, Witteemer, Erich, Barclay, Derek, Loughran, Patricia A, Zamora, Ruben, Vodovotz, Yoram
Publicado 2009

Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

por Tang, Da, Fu, Guang, Li, Wenbo, Sun, Ping, Loughran, Patricia A., Deng, Meihong, Scott, Melanie J., Billiar, Timothy R.
Publicado 2021

Interferon Regulatory Factor-1 (IRF1) activates autophagy to promote liver ischemia/reperfusion injury by inhibiting β-catenin in mice

por Yan, Bing, Luo, Jing, Kaltenmeier, Christof, Du, Qiang, Stolz, Donna B., Loughran, Patricia, Yan, Yihe, Cui, Xiao, Geller, David A.
Publicado 2020

The Receptor for Advanced Glycation End-products (RAGE) Sustains Autophagy and Limits Apoptosis, Promoting Pancreatic Tumor Cell Survival

por Kang, Rui, Tang, Daolin, Schapiro, Nicole E., Livesey, Kristen M., Farkas, Adam, Loughran, Patricia, Bierhaus, Angelika, Lotze, Michael T., Zeh, Herbert J.
Publicado 2009

Drag reducing polymers decrease hepatic injury and metastases after liver ischemia-reperfusion

por Tohme, Samer, Kameneva, Marina V., Yazdani, Hamza O., Sud, Vikas, Goswami, Julie, Loughran, Patricia, Huang, Hai, Simmons, Richard L., Tsung, Allan
Publicado 2017

Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding

por Lin, Minjie, Long, Jungke, Li, Wenbo, Yang, Chenxuan, Loughran, Patricia, O’Doherty, Robert, Billiar, Timothy R., Deng, Meihong, Scott, Melanie J.
Publicado 2020

Augmenting Autophagy to Treat Acute Kidney Injury during Endotoxemia in Mice

por Howell, Gina M., Gomez, Hernando, Collage, Richard D., Loughran, Patricia, Zhang, Xianghong, Escobar, Daniel A., Billiar, Timothy R., Zuckerbraun, Brian S., Rosengart, Matthew R.
Publicado 2013

Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA

por Dyer, Mitchell R., Chen, Qiwei, Haldeman, Shannon, Yazdani, Hamza, Hoffman, Rosemary, Loughran, Patricia, Tsung, Allan, Zuckerbraun, Brian S., Simmons, Richard L., Neal, Matthew D.
Publicado 2018

Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis

por Yang, Chenxuan, Sun, Ping, Deng, Meihong, Loughran, Patricia, Li, Wenbo, Yi, Zhongjie, Li, Shilai, Zhang, Xianghong, Fan, Jie, Billiar, Timothy R., Scott, Melanie J
Publicado 2019

Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation

por Long, Junke, Yang, Chenxuan, Zheng, Yawen, Loughran, Patricia, Guang, Fu, Li, Yiming, Liao, Hong, Scott, Melanie J., Tang, Daolin, Billiar, Timothy R., Deng, Meihong
Publicado 2020

Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated Pyroptosis

por Sun, Ping, Zhong, Jie, Liao, Hong, Loughran, Patricia, Mulla, Joud, Fu, Guang, Tang, Da, Fan, Jie, Billiar, Timothy R., Gao, Wentao, Scott, Melanie J.
Publicado 2021

Heme Oxygenase-2 Localizes to Mitochondria and Regulates Hypoxic Responses in Hepatocytes

por Waltz, Paul K., Kautza, Benjamin, Luciano, Jason, Dyer, Mitch, Stolz, Donna Beer, Loughran, Patricia, Neal, Matthew D., Sperry, Jason L., Rosengart, Matthew R., Zuckerbraun, Brian S.
Publicado 2018

Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine

por Sachdev, Ulka, Ferrari, Ricardo, Cui, Xiangdong, Pius, Abish, Sahu, Amrita, Reynolds, Michael, Liao, Hong, Sun, Ping, Shinde, Sunita, Ambrosio, Fabrisia, Shiva, Sruti, Loughran, Patricia, Scott, Melanie
Publicado 2020

Endogenous HMGB1 regulates autophagy

por Tang, Daolin, Kang, Rui, Livesey, Kristen M., Cheh, Chun-Wei, Farkas, Adam, Loughran, Patricia, Hoppe, George, Bianchi, Marco E., Tracey, Kevin J., Zeh, Herbert J., Lotze, Michael T.
Publicado 2010

The Receptor for Advanced Glycation End Products (RAGE) Enhances Autophagy and Neutrophil Extracellular Traps in Pancreatic Cancer

por Boone, Brian A., Orlichenko, Lidiya, Schapiro, Nicole E., Loughran, Patricia, Gianfrate, Gianmarino C., Ellis, Jarrod T., Singhi, Aatur D., Kang, Rui, Tang, Daolin, Lotze, Michael T., Zeh, Herbert J.
Publicado 2015

Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice

por Zettel, Kent, Korff, Sebastian, Zamora, Ruben, Morelli, Adrian E., Darwiche, Sophie, Loughran, Patricia A., Elson, Greg, Shang, Limin, Salgado-Pires, Susana, Scott, Melanie J., Vodovotz, Yoram, Billiar, Timothy R.
Publicado 2017

LPS Induces Active HMGB1 Release From Hepatocytes Into Exosomes Through the Coordinated Activities of TLR4 and Caspase-11/GSDMD Signaling

por Li, Wenbo, Deng, Meihong, Loughran, Patricia A., Yang, Muqing, Lin, Minjie, Yang, Chenxuan, Gao, Wentao, Jin, Shuqing, Li, Shilai, Cai, Jingjing, Lu, Ben, Billiar, Timothy R., Scott, Melanie J.
Publicado 2020

Hepatic Surgical Stress Promotes Systemic Immunothrombosis That Results in Distant Organ Injury

por Zhang, Hongji, Goswami, Julie, Varley, Patrick, van der Windt, Dirk J., Ren, Jinghua, Loughran, Patricia, Yazdani, Hamza, Neal, Matthew D., Simmons, Richard L., Zhang, Jinxiang, Tsung, Allan, Huang, Hai
Publicado 2020

Immune‐Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2–Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury

por Yi, Zhongjie, Deng, Meihong, Scott, Melanie J., Fu, Guang, Loughran, Patricia A., Lei, Zhao, Li, Shilai, Sun, Ping, Yang, Chenxuan, Li, Wenbo, Xu, Hongbo, Huang, Feizhou, Billiar, Timothy R.
Publicado 2020