Data-driven comorbidity analysis of 100 common disorders reveals patient subgroups with differing mortality risks and laboratory correlates

por Koskinen, Miika, Salmi, Jani K., Loukola, Anu, Mäkelä, Mika J., Sinisalo, Juha, Carpén, Olli, Renkonen, Risto
Publicado 2022

Systematic Analysis of Circadian Genes in a Population-Based Sample Reveals Association of TIMELESS with Depression and Sleep Disturbance

por Utge, Siddheshwar J., Soronen, Pia, Loukola, Anu, Kronholm, Erkki, Ollila, Hanna M., Pirkola, Sami, Porkka-Heiskanen, Tarja, Partonen, Timo, Paunio, Tiina
Publicado 2010

Genome‐wide time‐to‐event analysis on smoking progression stages in a family‐based study

por He, Liang, Pitkäniemi, Janne, Heikkilä, Kauko, Chou, Yi‐Ling, Madden, Pamela A.F., Korhonen, Tellervo, Sarin, Antti‐Pekka, Ripatti, Samuli, Kaprio, Jaakko, Loukola, Anu
Publicado 2016

The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study

por Taylor, Amy E, Richmond, Rebecca C, Palviainen, Teemu, Loukola, Anu, Wootton, Robyn E, Kaprio, Jaakko, Relton, Caroline L, Davey Smith, George, Munafò, Marcus R
Publicado 2019

Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci

por Gupta, Richa, van Dongen, Jenny, Fu, Yu, Abdellaoui, Abdel, Tyndale, Rachel F., Velagapudi, Vidya, Boomsma, Dorret I., Korhonen, Tellervo, Kaprio, Jaakko, Loukola, Anu, Ollikainen, Miina
Publicado 2019

Genome‐wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway

por Hällfors, Jenni, Palviainen, Teemu, Surakka, Ida, Gupta, Richa, Buchwald, Jadwiga, Raevuori, Anu, Ripatti, Samuli, Korhonen, Tellervo, Jousilahti, Pekka, Madden, Pamela A.F., Kaprio, Jaakko, Loukola, Anu
Publicado 2018

Interaction of early environment, gender and genes of monoamine neurotransmission in the aetiology of depression in a large population-based Finnish birth cohort

por Nyman, Emma S, Sulkava, Sonja, Soronen, Pia, Miettunen, Jouko, Loukola, Anu, Leppä, Virpi, Joukamaa, Matti, Mäki, Pirjo, Järvelin, Marjo-Riitta, Freimer, Nelson, Peltonen, Leena, Veijola, Juha, Paunio, Tiina
Publicado 2011

Polygenic Scores Predict Alcohol Problems in an Independent Sample and Show Moderation by the Environment

por Salvatore, Jessica E., Aliev, Fazil, Edwards, Alexis C., Evans, David M., Macleod, John, Hickman, Matthew, Lewis, Glyn, Kendler, Kenneth S., Loukola, Anu, Korhonen, Tellervo, Latvala, Antti, Rose, Richard J., Kaprio, Jaakko, Dick, Danielle M.
Publicado 2014

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism

por Loukola, Anu, Buchwald, Jadwiga, Gupta, Richa, Palviainen, Teemu, Hällfors, Jenni, Tikkanen, Emmi, Korhonen, Tellervo, Ollikainen, Miina, Sarin, Antti-Pekka, Ripatti, Samuli, Lehtimäki, Terho, Raitakari, Olli, Salomaa, Veikko, Rose, Richard J., Tyndale, Rachel F., Kaprio, Jaakko
Publicado 2015

Role of Nicotine Dependence in the Association between the Dopamine Receptor Gene DRD3 and Major Depressive Disorder

por Korhonen, Tellervo, Loukola, Anu, Wedenoja, Juho, Nyman, Emma, Latvala, Antti, Broms, Ulla, Häppölä, Anja, Paunio, Tiina, Schrage, Andrew J., Vink, Jaqueline M., Mbarek, Hamdi, Boomsma, Dorret I., Penninx, Brenda W. J. H., Pergadia, Michele L., Madden, Pamela A. F., Kaprio, Jaakko
Publicado 2014

Genome-wide association study on detailed profiles of smoking behavior and nicotine dependence in a twin sample

por Loukola, Anu, Wedenoja, Juho, Keskitalo-Vuokko, Kaisu, Broms, Ulla, Korhonen, Tellervo, Ripatti, Samuli, Sarin, Antti-Pekka, Pitkäniemi, Janne, He, Liang, Häppölä, Anja, Heikkilä, Kauko, Chou, Yi-Ling, Pergadia, Michele L, Heath, Andrew C, Montgomery, Grant W, Martin, Nicholas G, Madden, Pamela AF, Kaprio, Jaakko
Publicado 2013

Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss

por Vuckovic, Dragana, Dawson, Sally, Scheffer, Deborah I., Rantanen, Taina, Morgan, Anna, Di Stazio, Mariateresa, Vozzi, Diego, Nutile, Teresa, Concas, Maria P., Biino, Ginevra, Nolan, Lisa, Bahl, Aileen, Loukola, Anu, Viljanen, Anne, Davis, Adrian, Ciullo, Marina, Corey, David P., Pirastu, Mario, Gasparini, Paolo, Girotto, Giorgia
Publicado 2015

Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent

por Buchwald, Jadwiga, Chenoweth, Meghan J., Palviainen, Teemu, Zhu, Gu, Benner, Christian, Gordon, Scott, Korhonen, Tellervo, Ripatti, Samuli, Madden, Pamela A. F., Lehtimäki, Terho, Raitakari, Olli T., Salomaa, Veikko, Rose, Richard J., George, Tony P., Lerman, Caryn, Pirinen, Matti, Martin, Nicholas G., Kaprio, Jaakko, Loukola, Anu, Tyndale, Rachel F.
Publicado 2020

Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke

por Leskelä, Jaakko, Toppila, Iiro, Härma, Mari‐Anne, Palviainen, Teemu, Salminen, Aino, Sandholm, Niina, Pietiäinen, Milla, Kopra, Elisa, Pais de Barros, Jean‐Paul, Lassenius, Mariann I., Kumar, Anmol, Harjutsalo, Valma, Roslund, Kajsa, Forsblom, Carol, Loukola, Anu, Havulinna, Aki S., Lagrost, Laurent, Salomaa, Veikko, Groop, Per‐Henrik, Perola, Markus, Kaprio, Jaakko, Lehto, Markku, Pussinen, Pirkko J.
Publicado 2021

Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight

por Beck, Jeffrey J, Pool, René, van de Weijer, Margot, Chen, Xu, Krapohl, Eva, Gordon, Scott D, Nygaard, Marianne, Debrabant, Birgit, Palviainen, Teemu, van der Zee, Matthijs D, Baselmans, Bart, Finnicum, Casey T, Yi, Lu, Lundström, Sebastian, van Beijsterveldt, Toos, Christiansen, Lene, Heikkilä, Kauko, Kittelsrud, Julie, Loukola, Anu, Ollikainen, Miina, Christensen, Kaare, Martin, Nicholas G, Plomin, Robert, Nivard, Michel, Bartels, Meike, Dolan, Conor, Willemsen, Gonneke, de Geus, Eco, Almqvist, Catarina, Magnusson, Patrik K E, Mbarek, Hamdi, Ehli, Erik A, Boomsma, Dorret I, Hottenga, Jouke-Jan
Publicado 2021

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2

por Ware, Jennifer J., Chen, Xiangning, Vink, Jacqueline, Loukola, Anu, Minica, Camelia, Pool, Rene, Milaneschi, Yuri, Mangino, Massimo, Menni, Cristina, Chen, Jingchun, Peterson, Roseann E., Auro, Kirsi, Lyytikäinen, Leo-Pekka, Wedenoja, Juho, Stiby, Alexander I., Hemani, Gibran, Willemsen, Gonneke, Hottenga, Jouke Jan, Korhonen, Tellervo, Heliövaara, Markku, Perola, Markus, Rose, Richard J., Paternoster, Lavinia, Timpson, Nic, Wassenaar, Catherine A., Zhu, Andy Z. X., Davey Smith, George, T. Raitakari, Olli, Lehtimäki, Terho, Kähönen, Mika, Koskinen, Seppo, Spector, Timothy, Penninx, Brenda W. J. H., Salomaa, Veikko, Boomsma, Dorret I., Tyndale, Rachel F., Kaprio, Jaakko, Munafò, Marcus R.
Publicado 2016

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence

por Hancock, Dana B., Guo, Yuelong, Reginsson, Gunnar W., Gaddis, Nathan C., Lutz, Sharon M., Sherva, Richard, Loukola, Anu, Minica, Camelia, Markunas, Christina A., Han, Younghun, Young, Kendra A., Gudbjartsson, Daniel F., Gu, Fangyi, McNeil, Daniel W., Qaiser, Beenish, Glasheen, Cristie, Olson, Sean, Landi, Maria Teresa, Madden, Pamela A. F., Farrer, Lindsay A., Vink, Jacqueline, Saccone, Nancy L., Neale, Michael C., Kranzler, Henry R., McKay, James, Hung, Rayjean J., Amos, Christopher I., Marazita, Mary L., Boomsma, Dorret I., Baker, Timothy B., Gelernter, Joel, Kaprio, Jaakko, Caporaso, Neil E., Thorgeirsson, Thorgeir E., Hokanson, John E., Bierut, Laura J., Stefansson, Kari, Johnson, Eric O.
Publicado 2017

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

por Taylor, Amy E, Fluharty, Meg E, Bjørngaard, Johan H, Gabrielsen, Maiken Elvestad, Skorpen, Frank, Marioni, Riccardo E, Campbell, Archie, Engmann, Jorgen, Mirza, Saira Saeed, Loukola, Anu, Laatikainen, Tiina, Partonen, Timo, Kaakinen, Marika, Ducci, Francesca, Cavadino, Alana, Husemoen, Lise Lotte N, Ahluwalia, Tarunveer Singh, Jacobsen, Rikke Kart, Skaaby, Tea, Ebstrup, Jeanette Frost, Mortensen, Erik Lykke, Minica, Camelia C, Vink, Jacqueline M, Willemsen, Gonneke, Marques-Vidal, Pedro, Dale, Caroline E, Amuzu, Antoinette, Lennon, Lucy T, Lahti, Jari, Palotie, Aarno, Räikkönen, Katri, Wong, Andrew, Paternoster, Lavinia, Wong, Angelita Pui-Yee, Horwood, L John, Murphy, Michael, Johnstone, Elaine C, Kennedy, Martin A, Pausova, Zdenka, Paus, Tomáš, Ben-Shlomo, Yoav, Nohr, Ellen A, Kuh, Diana, Kivimaki, Mika, Eriksson, Johan G, Morris, Richard W, Casas, Juan P, Preisig, Martin, Boomsma, Dorret I, Linneberg, Allan, Power, Chris, Hyppönen, Elina, Veijola, Juha, Jarvelin, Marjo-Riitta, Korhonen, Tellervo, Tiemeier, Henning, Kumari, Meena, Porteous, David J, Hayward, Caroline, Romundstad, Pål R, Smith, George Davey, Munafò, Marcus R
Publicado 2014

Meta-analysis of exome array data identifies six novel genetic loci for lung function

por Jackson, Victoria E., Latourelle, Jeanne C., Wain, Louise V., Smith, Albert V., Grove, Megan L., Bartz, Traci M., Obeidat, Ma'en, Province, Michael A., Gao, Wei, Qaiser, Beenish, Porteous, David J., Cassano, Patricia A., Ahluwalia, Tarunveer S., Grarup, Niels, Li, Jin, Altmaier, Elisabeth, Marten, Jonathan, Harris, Sarah E., Manichaikul, Ani, Pottinger, Tess D., Li-Gao, Ruifang, Lind-Thomsen, Allan, Mahajan, Anubha, Lahousse, Lies, Imboden, Medea, Teumer, Alexander, Prins, Bram, Lyytikäinen, Leo-Pekka, Eiriksdottir, Gudny, Franceschini, Nora, Sitlani, Colleen M., Brody, Jennifer A., Bossé, Yohan, Timens, Wim, Kraja, Aldi, Loukola, Anu, Tang, Wenbo, Liu, Yongmei, Bork-Jensen, Jette, Justesen, Johanne M., Linneberg, Allan, Lange, Leslie A., Rawal, Rajesh, Karrasch, Stefan, Huffman, Jennifer E., Smith, Blair H., Davies, Gail, Burkart, Kristin M., Mychaleckyj, Josyf C., Bonten, Tobias N., Enroth, Stefan, Lind, Lars, Brusselle, Guy G., Kumar, Ashish, Stubbe, Beate, Kähönen, Mika, Wyss, Annah B., Psaty, Bruce M., Heckbert, Susan R., Hao, Ke, Rantanen, Taina, Kritchevsky, Stephen B., Lohman, Kurt, Skaaby, Tea, Pisinger, Charlotta, Hansen, Torben, Schulz, Holger, Polasek, Ozren, Campbell, Archie, Starr, John M., Rich, Stephen S., Mook-Kanamori, Dennis O., Johansson, Åsa, Ingelsson, Erik, Uitterlinden, André G., Weiss, Stefan, Raitakari, Olli T., Gudnason, Vilmundur, North, Kari E., Gharib, Sina A., Sin, Don D., Taylor, Kent D., O'Connor, George T., Kaprio, Jaakko, Harris, Tamara B., Pederson, Oluf, Vestergaard, Henrik, Wilson, James G., Strauch, Konstantin, Hayward, Caroline, Kerr, Shona, Deary, Ian J., Barr, R. Graham, de Mutsert, Renée, Gyllensten, Ulf, Morris, Andrew P., Ikram, M. Arfan, Probst-Hensch, Nicole, Gläser, Sven, Zeggini, Eleftheria, Lehtimäki, Terho, Strachan, David P., Dupuis, Josée, Morrison, Alanna C., Hall, Ian P., Tobin, Martin D., London, Stephanie J.
Publicado 2018

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

por Lahti, Jari, Tuominen, Samuli, Yang, Qiong, Pergola, Giulio, Ahmad, Shahzad, Amin, Najaf, Armstrong, Nicola J., Beiser, Alexa, Bey, Katharina, Bis, Joshua C., Boerwinkle, Eric, Bressler, Jan, Campbell, Archie, Campbell, Harry, Chen, Qiang, Corley, Janie, Cox, Simon R., Davies, Gail, De Jager, Philip L., Derks, Eske M., Faul, Jessica D., Fitzpatrick, Annette L., Fohner, Alison E., Ford, Ian, Fornage, Myriam, Gerring, Zachary, Grabe, Hans J., Grodstein, Francine, Gudnason, Vilmundur, Simonsick, Eleanor, Holliday, Elizabeth G., Joshi, Peter K., Kajantie, Eero, Kaprio, Jaakko, Karell, Pauliina, Kleineidam, Luca, Knol, Maria J., Kochan, Nicole A., Kwok, John B., Leber, Markus, Lam, Max, Lee, Teresa, Li, Shuo, Loukola, Anu, Luck, Tobias, Marioni, Riccardo E., Mather, Karen A., Medland, Sarah, Mirza, Saira S., Nalls, Mike A., Nho, Kwangsik, O’Donnell, Adrienne, Oldmeadow, Christopher, Painter, Jodie, Pattie, Alison, Reppermund, Simone, Risacher, Shannon L., Rose, Richard J., Sadashivaiah, Vijay, Scholz, Markus, Satizabal, Claudia L., Schofield, Peter W., Schraut, Katharina E., Scott, Rodney J., Simino, Jeannette, Smith, Albert V., Smith, Jennifer A., Stott, David J., Surakka, Ida, Teumer, Alexander, Thalamuthu, Anbupalam, Trompet, Stella, Turner, Stephen T., van der Lee, Sven J., Villringer, Arno, Völker, Uwe, Wilson, Robert S., Wittfeld, Katharina, Vuoksimaa, Eero, Xia, Rui, Yaffe, Kristine, Yu, Lei, Zare, Habil, Zhao, Wei, Ames, David, Attia, John, Bennett, David A., Brodaty, Henry, Chasman, Daniel I., Goldman, Aaron L., Hayward, Caroline, Ikram, M. Arfan, Jukema, J. Wouter, Kardia, Sharon L. R., Lencz, Todd, Loeffler, Markus, Mattay, Venkata S., Palotie, Aarno, Psaty, Bruce M., Ramirez, Alfredo, Ridker, Paul M., Riedel-Heller, Steffi G., Sachdev, Perminder S., Saykin, Andrew J., Scherer, Martin, Schofield, Peter R., Sidney, Stephen, Starr, John M., Trollor, Julian, Ulrich, William, Wagner, Michael, Weir, David R., Wilson, James F., Wright, Margaret J., Weinberger, Daniel R., Debette, Stephanie, Eriksson, Johan G., Mosley, Thomas H., Launer, Lenore J., van Duijn, Cornelia M., Deary, Ian J., Seshadri, Sudha, Räikkönen, Katri
Publicado 2022