Editorial: Mapping enzyme activity: from novel diagnostics to target-based therapeutics, how activity-based probes are improving our understanding of biological catalysts

por Lourenço, André Luiz
Publicado 2023

Marine Diterpenes: Molecular Modeling of Thrombin Inhibitors with Potential Biotechnological Application as an Antithrombotic

por Pereira, Rebeca Cristina Costa, Lourenço, André Luiz, Terra, Luciana, Abreu, Paula Alvarez, Laneuville Teixeira, Valéria, Castro, Helena Carla
Publicado 2017

Platelets: Still a Therapeutical Target for Haemostatic Disorders

por Geraldo, Reinaldo Barros, Sathler, Plínio Cunha, Lourenço, André Luiz, Saito, Max Seidy, Cabral, Lucio M., Rampelotto, Pabulo Henrique, Castro, Helena Carla
Publicado 2014

4532 Pancreatic Cyst Risk Stratification for Early Detection of Pancreatic Cancer Using Quantitative Radiomics and Activity-Based Biomarkers

por Hernandez, Sophia, Lourenco, Andre Luiz, Calabrese, Evan, York, Tyler, Glencer, Alexa, Behr, Spencer, Wang, Zhen Jane, Koay, Eugene, Craik, Charles, Kirkwood, Kimberly
Publicado 2020

High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions

por Lourenço, André Luiz, Chuo, Shih-Wei, Bohn, Markus F., Hann, Byron, Khan, Shireen, Yevalekar, Neha, Patel, Nitin, Yang, Teddy, Xu, Lina, Lv, Dandan, Drakas, Robert, Lively, Sarah, Craik, Charles S.
Publicado 2023

In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET

por Zhao, Ning, Bardine, Conner, Lourenço, André Luiz, Wang, Yung-hua, Huang, Yangjie, Cleary, Simon J., Wilson, David M., Oh, David Y., Fong, Lawrence, Looney, Mark R., Evans, Michael J., Craik, Charles S.
Publicado 2021

Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes

por Sevillano, Natalia, Green, Evan M., Votteler, Jörg, Kim, Dong Young, Ren, Xuefeng, Yang, Bei, Liu, Xi, Lourenço, André Luiz, Hurley, James H., Farr-Jones, Shauna, Gross, John D., Cheng, Yifan, Craik, Charles S.
Publicado 2021

Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer

por Harel, Efrat T., Drake, Penelope M., Barfield, Robyn M., Lui, Irene, Farr-Jones, Shauna, Van’t Veer, Laura, Gartner, Zev J., Green, Evan M., Lourenço, André Luiz, Cheng, Yifan, Hann, Byron C., Rabuka, David, Craik, Charles S.
Publicado 2019

Synthesis and Antiplatelet Activity of Antithrombotic Thiourea Compounds: Biological and Structure-Activity Relationship Studies

por Lourenço, André Luiz, Saito, Max Seidy, Dorneles, Luís Eduardo Gomes, Viana, Gil Mendes, Sathler, Plínio Cunha, de Sequeira Aguiar, Lúcia Cruz, de Pádula, Marcelo, Domingos, Thaisa Francielle Souza, Fraga, Aline Guerra Manssour, Rodrigues, Carlos Rangel, de Sousa, Valeria Pereira, Castro, Helena Carla, Cabral, Lucio Mendes
Publicado 2015

A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

por Mahoney, Matthew, Damalanka, Vishnu C., Tartell, Michael A., Chung, Dong hee, Lourenço, André Luiz, Pwee, Dustin, Mayer Bridwell, Anne E., Hoffmann, Markus, Voss, Jorine, Karmakar, Partha, Azouz, Nurit P., Klingler, Andrea M., Rothlauf, Paul W., Thompson, Cassandra E., Lee, Melody, Klampfer, Lidija, Stallings, Christina L., Rothenberg, Marc E., Pöhlmann, Stefan, Whelan, Sean P. J., O’Donoghue, Anthony J., Craik, Charles S., Janetka, James W.
Publicado 2021