Established and Emerging Biomarkers in Cutaneous Malignant Melanoma

por Verykiou, Stamatina, Ellis, Robert A, Lovat, Penny E
Publicado 2014

Prognostic Impact of Autophagy Biomarkers for Cutaneous Melanoma

por Tang, Diana Y. L., Ellis, Robert A., Lovat, Penny E.
Publicado 2016

Fateful music from a talented orchestra with a wicked conductor: Connection between oncogenic BRAF, ER stress, and autophagy in human melanoma

por Giglio, Paola, Fimia, Gian Maria, Lovat, Penny E, Piacentini, Mauro, Corazzari, Marco
Publicado 2015

Health professional and patient views of a novel prognostic test for melanoma: A theoretically informed qualitative study

por Lecouturier, Jan, Bosomworth, Helen, Labus, Marie, Ellis, Rob A., Lovat, Penny E.
Publicado 2022

TP53 mutant cell lines selected for resistance to MDM2 inhibitors retain growth inhibition by MAPK pathway inhibitors but a reduced apoptotic response

por Wu, Chiao-En, Koay, Tsin Shue, Ho, Yi-Hsuan, Lovat, Penny, Lunec, John
Publicado 2019

ATM Dependent DUSP6 Modulation of p53 Involved in Synergistic Targeting of MAPK and p53 Pathways with Trametinib and MDM2 Inhibitors in Cutaneous Melanoma

por Wu, Chiao-En, Koay, Tsin Shue, Esfandiari, Arman, Ho, Yi-Hsuan, Lovat, Penny, Lunec, John
Publicado 2018

Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma

por Wu, Chiao-En, Esfandiari, Arman, Ho, Yi-Hsuan, Wang, Nan, Mahdi, Ahmed Khairallah, Aptullahoglu, Erhan, Lovat, Penny, Lunec, John
Publicado 2018

Prognostic impact of p62 expression in cutaneous malignant melanoma

por Ellis, Robert A, Horswell, Stuart, Ness, Tom, Lumsdon, Jonathan, Tooze, Sharon A, Kirkham, Nigel, Armstrong, Jane L, Lovat, Penny E
Publicado 2013

Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca(2+)-PPP3/calcineurin-TFEB axis

por Zummo, Francesco P, Krishnanda, Stanislaus I, Georgiou, Merilin, O’Harte, Finbarr PM, Parthsarathy, Vadivel, Cullen, Kirsty S, Honkanen-Scott, Minna, Shaw, James AM, Lovat, Penny E, Arden, Catherine
Publicado 2021

Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses

por Widdrington, John D., Gomez-Duran, Aurora, Pyle, Angela, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Baudouin, Simon V., Rostron, Anthony J., Lovat, Penny E., Chinnery, Patrick F., Simpson, A. John
Publicado 2018

Predictive accuracy of risk prediction models for recurrence, metastasis and survival for early-stage cutaneous melanoma: a systematic review

por Kunonga, Tafadzwa Patience, Kenny, R P W, Astin, Margaret, Bryant, Andrew, Kontogiannis, Vasileios, Coughlan, Diarmuid, Richmond, Catherine, Eastaugh, Claire H, Beyer, Fiona R, Pearson, Fiona, Craig, Dawn, Lovat, Penny, Vale, Luke, Ellis, Robert
Publicado 2023

HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1

por Antonioli, Manuela, Pagni, Benedetta, Vescovo, Tiziana, Ellis, Rob, Cosway, Benjamin, Rollo, Francesca, Bordoni, Veronica, Agrati, Chiara, Labus, Marie, Covello, Renato, Benevolo, Maria, Ippolito, Giuseppe, Robinson, Max, Piacentini, Mauro, Lovat, Penny, Fimia, Gian Maria
Publicado 2020

Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing

por Carroll, Bernadette, Nelson, Glyn, Rabanal-Ruiz, Yoana, Kucheryavenko, Olena, Dunhill-Turner, Natasha A., Chesterman, Charlotte C., Zahari, Qabil, Zhang, Tong, Conduit, Sarah E., Mitchell, Christina A., Maddocks, Oliver D.K., Lovat, Penny, von Zglinicki, Thomas, Korolchuk, Viktor I.
Publicado 2017

Programmed cell death-1 receptor-mediated regulation of Tbet(+)NK1.1(−) innate lymphoid cells within the tumor microenvironment

por Lim, Jing Xuan, Lai, Chester Y., Mallett, Grace E., McDonald, David, Hulme, Gillian, Laba, Stephanie, Shapanis, Andrew, Payne, Megan, Patterson, Warren, Alexander, Michael, Coxhead, Jonathan, Filby, Andrew, Plummer, Ruth, Lovat, Penny E., Sciume, Giuseppe, Healy, Eugene, Amarnath, Shoba
Publicado 2023

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization

por Hernández-Tiedra, Sonia, Fabriàs, Gemma, Dávila, David, Salanueva, Íñigo J., Casas, Josefina, Montes, L. Ruth, Antón, Zuriñe, García-Taboada, Elena, Salazar-Roa, María, Lorente, Mar, Nylandsted, Jesper, Armstrong, Jane, López-Valero, Israel, McKee, Christopher S., Serrano-Puebla, Ana, García-López, Roberto, González-Martínez, José, Abad, José L., Hanada, Kentaro, Boya, Patricia, Goñi, Félix, Guzmán, Manuel, Lovat, Penny, Jäättelä, Marja, Alonso, Alicia, Velasco, Guillermo
Publicado 2016