Emerging treatment options for cryptosporidiosis

por Love, Melissa S., Choy, Robert K.M.
Publicado 2021

A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis

por Love, Melissa S., Beasley, Federico C., Jumani, Rajiv S., Wright, Timothy M., Chatterjee, Arnab K., Huston, Christopher D., Schultz, Peter G., McNamara, Case W.
Publicado 2017

Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy

por Michaels, Samantha A., Hulverson, Matthew A., Whitman, Grant R., Tran, Linh T., Choi, Ryan, Fan, Erkang, McNamara, Case W., Love, Melissa S., Ojo, Kayode K.
Publicado 2022

Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition

por Lee, Seungheon, Love, Melissa S., Modukuri, Ramkumar, Chatterjee, Arnab K., Huerta, Lauren, Lawson, Ann P., McNamara, Case W., Mead, Jan R., Hedstrom, Lizbeth, Cuny, Gregory D.
Publicado 2023

A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors

por Jumani, Rajiv S., Hasan, Muhammad M., Stebbins, Erin E., Donnelly, Liam, Miller, Peter, Klopfer, Connor, Bessoff, Kovi, Teixeira, Jose E., Love, Melissa S., McNamara, Case W., Huston, Christopher D.
Publicado 2019

Molecular Testing for Mycoplasma genitalium in the United States: Results from the AMES Prospective Multicenter Clinical Study

por Gaydos, Charlotte A., Manhart, Lisa E., Taylor, Stephanie N., Lillis, Rebecca A., Hook, Edward W., Klausner, Jeffrey D., Remillard, Carmelle V., Love, Melissa, McKinney, Byron, Getman, Damon K.
Publicado 2019

Characteristics of Mycoplasma genitalium Urogenital Infections in a Diverse Patient Sample from the United States: Results from the Aptima Mycoplasma genitalium Evaluation Study (A...

por Manhart, Lisa E., Gaydos, Charlotte A., Taylor, Stephanie N., Lillis, Rebecca A., Hook, Edward W., Klausner, Jeffrey D., Remillard, Carmelle V., Love, Melissa, McKinney, Byron, Getman, Damon K.
Publicado 2020

Iron limitation in M. tuberculosis has broad impact on central carbon metabolism

por Theriault, Monique E., Pisu, Davide, Wilburn, Kaley M., Lê-Bury, Gabrielle, MacNamara, Case W., Michael Petrassi, H., Love, Melissa, Rock, Jeremy M., VanderVen, Brian C., Russell, David G.
Publicado 2022

Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis

por Wilburn, Kaley M., Montague, Christine R., Qin, Bo, Woods, Ashley K., Love, Melissa S., McNamara, Case W., Schultz, Peter G., Southard, Teresa L., Huang, Lu, Petrassi, H. Michael, VanderVen, Brian C.
Publicado 2022

Pharmacokinetics and Pharmacodynamics of Clofazimine for Treatment of Cryptosporidiosis

por Zhang, Cindy X., Love, Melissa S., McNamara, Case W., Chi, Victor, Woods, Ashley K., Joseph, Sean, Schaefer, Deborah A., Betzer, Dana P., Riggs, Michael W., Iroh Tam, Pui-Ying, Van Voorhis, Wesley C., Arnold, Samuel L. M.
Publicado 2022

Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis

por Lunde, Christopher S., Stebbins, Erin E., Jumani, Rajiv S., Hasan, Md Mahmudul, Miller, Peter, Barlow, John, Freund, Yvonne R., Berry, Pamela, Stefanakis, Rianna, Gut, Jiri, Rosenthal, Philip J., Love, Melissa S., McNamara, Case W., Easom, Eric, Plattner, Jacob J., Jacobs, Robert T., Huston, Christopher D.
Publicado 2019

The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis

por Janes, Jeff, Young, Megan E., Chen, Emily, Rogers, Nicole H., Burgstaller-Muehlbacher, Sebastian, Hughes, Laura D., Love, Melissa S., Hull, Mitchell V., Kuhen, Kelli L., Woods, Ashley K., Joseph, Sean B., Petrassi, H. Michael, McNamara, Case W., Tremblay, Matthew S., Su, Andrew I., Schultz, Peter G., Chatterjee, Arnab K.
Publicado 2018

Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance

por Ottilie, Sabine, Luth, Madeline R., Hellemann, Erich, Goldgof, Gregory M., Vigil, Eddy, Kumar, Prianka, Cheung, Andrea L., Song, Miranda, Godinez-Macias, Karla P., Carolino, Krypton, Yang, Jennifer, Lopez, Gisel, Abraham, Matthew, Tarsio, Maureen, LeBlanc, Emmanuelle, Whitesell, Luke, Schenken, Jake, Gunawan, Felicia, Patel, Reysha, Smith, Joshua, Love, Melissa S., Williams, Roy M., McNamara, Case W., Gerwick, William H., Ideker, Trey, Suzuki, Yo, Wirth, Dyann F., Lukens, Amanda K., Kane, Patricia M., Cowen, Leah E., Durrant, Jacob D., Winzeler, Elizabeth A.
Publicado 2022

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

por Baragaña, Beatriz, Forte, Barbara, Choi, Ryan, Nakazawa Hewitt, Stephen, Bueren-Calabuig, Juan A., Pisco, João Pedro, Peet, Caroline, Dranow, David M., Robinson, David A., Jansen, Chimed, Norcross, Neil R., Vinayak, Sumiti, Anderson, Mark, Brooks, Carrie F., Cooper, Caitlin A., Damerow, Sebastian, Delves, Michael, Dowers, Karen, Duffy, James, Edwards, Thomas E., Hallyburton, Irene, Horst, Benjamin G., Hulverson, Matthew A., Ferguson, Liam, Jiménez-Díaz, María Belén, Jumani, Rajiv S., Lorimer, Donald D., Love, Melissa S., Maher, Steven, Matthews, Holly, McNamara, Case W., Miller, Peter, O’Neill, Sandra, Ojo, Kayode K., Osuna-Cabello, Maria, Pinto, Erika, Post, John, Riley, Jennifer, Rottmann, Matthias, Sanz, Laura M., Scullion, Paul, Sharma, Arvind, Shepherd, Sharon M., Shishikura, Yoko, Simeons, Frederick R. C., Stebbins, Erin E., Stojanovski, Laste, Straschil, Ursula, Tamaki, Fabio K., Tamjar, Jevgenia, Torrie, Leah S., Vantaux, Amélie, Witkowski, Benoît, Wittlin, Sergio, Yogavel, Manickam, Zuccotto, Fabio, Angulo-Barturen, Iñigo, Sinden, Robert, Baum, Jake, Gamo, Francisco-Javier, Mäser, Pascal, Kyle, Dennis E., Winzeler, Elizabeth A., Myler, Peter J., Wyatt, Paul G., Floyd, David, Matthews, David, Sharma, Amit, Striepen, Boris, Huston, Christopher D., Gray, David W., Fairlamb, Alan H., Pisliakov, Andrei V., Walpole, Chris, Read, Kevin D., Van Voorhis, Wesley C., Gilbert, Ian H.
Publicado 2019