The use of Bayesian design in two trials in rare cancers

por Dutton, Peter, Love, Sharon, Faleti, Ade, Hassan, Bass
Publicado 2015

IntReALL HR and the benefits of adaptive design

por Holmes, Jane, Love, Sharon, Saha, Vaskar, von Stackelberg, Arend
Publicado 2015

Challenges in implementing model-based phase I designs in a grant-funded clinical trials unit

por Frangou, Eleni, Holmes, Jane, Love, Sharon, McGregor, Naomi, Hawkins, Maria
Publicado 2017

Monitoring in practice – How are UK academic clinical trials monitored? A survey

por Love, Sharon B., Yorke-Edwards, Victoria, Lensen, Sarah, Sydes, Matthew R.
Publicado 2020

FOXFIRE protocol: an open-label, randomised, phase III trial of 5-fluorouracil, oxaliplatin and folinic acid (OxMdG) with or without interventional Selective Internal Radiation The...

por Dutton, Susan J, Kenealy, Nicola, Love, Sharon B, Wasan, Harpreet S, Sharma, Ricky A
Publicado 2014

Protecting blinded trials in electronic hospital systems

por Sydes, Matthew R, Wong, Wai Keong, Bakhai, Ameet, Joffe, Nicola, Love, Sharon B
Publicado 2022

Uptake of the multi-arm multi-stage (MAMS) adaptive platform approach: a trial-registry review of late-phase randomised clinical trials

por Noor, Nurulamin M, Love, Sharon B, Isaacs, Talia, Kaplan, Richard, Parmar, Mahesh K B, Sydes, Matthew R
Publicado 2022

Lack of transparent reporting of trial monitoring approaches in randomised controlled trials: A systematic review of contemporary protocol papers

por Hsieh, Shao-Fan, Yorke-Edwards, Victoria, Murray, Macey L, Diaz-Montana, Carlos, Love, Sharon B, Sydes, Matthew R
Publicado 2023

Practicalities in running early-phase trials using the time-to-event continual reassessment method (TiTE-CRM) for interventions with long toxicity periods using two radiotherapy on...

por van Werkhoven, Erik, Hinsley, Samantha, Frangou, Eleni, Holmes, Jane, de Haan, Rosemarie, Hawkins, Maria, Brown, Sarah, Love, Sharon B
Publicado 2020

Use of routinely collected health data in randomised clinical trials: comparison of trial-specific death data in the BOSS trial with NHS Digital data

por Love, Sharon B., Kilanowski, Anna, Yorke-Edwards, Victoria, Old, Oliver, Barr, Hugh, Stokes, Clive, Kendall, Catherine, Sydes, Matthew R.
Publicado 2021

Monitoring advances including consent: learning from COVID-19 trials and other trials running in UKCRC registered clinical trials units during the pandemic

por Love, Sharon B., Armstrong, Emma, Bayliss, Carrie, Boulter, Melanie, Fox, Lisa, Grumett, Joanne, Rafferty, Patricia, Temesi, Barbara, Wills, Krista, Corkhill, Andrea
Publicado 2021

Making a distinction between data cleaning and central monitoring in clinical trials

por Love, Sharon B, Yorke-Edwards, Victoria, Diaz-Montana, Carlos, Murray, Macey L, Masters, Lindsey, Gabriel, Michelle, Joffe, Nicola, Sydes, Matthew R
Publicado 2021

EnROL: A multicentre randomised trial of conventional versus laparoscopic surgery for colorectal cancer within an enhanced recovery programme

por Kennedy, Robin H, Francis, Anne, Dutton, Susan, Love, Sharon, Pearson, Sarah, Blazeby, Jane M, Quirke, Philip, Franks, Peter J, Kerr, David J
Publicado 2012

Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment...

por Virdee, Pradeep S, Moschandreas, Joanna, Gebski, Val, Love, Sharon B, Francis, E Anne, Wasan, Harpreet S, van Hazel, Guy, Gibbs, Peter, Sharma, Ricky A
Publicado 2017

Data provenance and integrity of health-care systems data for clinical trials

por Murray, Macey L, Love, Sharon B, Carpenter, James R, Hartley, Suzanne, Landray, Martin J, Mafham, Marion, Parmar, Mahesh K B, Pinches, Heather, Sydes, Matthew R
Publicado 2022

Accessing routinely collected health data to improve clinical trials: recent experience of access

por Macnair, Archie, Love, Sharon B., Murray, Macey L., Gilbert, Duncan C., Parmar, Mahesh K. B., Denwood, Tom, Carpenter, James, Sydes, Matthew R., Langley, Ruth E., Cafferty, Fay H.
Publicado 2021

Access to routinely collected health data for clinical trials – review of successful data requests to UK registries

por Lensen, Sarah, Macnair, Archie, Love, Sharon B., Yorke-Edwards, Victoria, Noor, Nurulamin M., Martyn, Meredith, Blenkinsop, Alexandra, Diaz-Montana, Carlos, Powell, Graham, Williamson, Elizabeth, Carpenter, James, Sydes, Matthew R.
Publicado 2020

What is the purpose of clinical trial monitoring?

por Love, Sharon B., Yorke-Edwards, Victoria, Ward, Elizabeth, Haydock, Rebecca, Keen, Katie, Biggs, Katie, Gopalakrishnan, Gosala, Marsh, Lucy, O’Sullivan, Lydia, Fox, Lisa, Payerne, Estelle, Hood, Kerenza, Meakin, Garry
Publicado 2022

Embracing model-based designs for dose-finding trials

por Love, Sharon B, Brown, Sarah, Weir, Christopher J, Harbron, Chris, Yap, Christina, Gaschler-Markefski, Birgit, Matcham, James, Caffrey, Louise, McKevitt, Christopher, Clive, Sally, Craddock, Charlie, Spicer, James, Cornelius, Victoria
Publicado 2017

Dual Erb B Inhibition in Oesophago-gastric Cancer (DEBIOC): A phase I dose escalating safety study and randomised dose expansion of AZD8931 in combination with oxaliplatin and cape...

por Thomas, Anne, Virdee, Pradeep S., Eatock, Martin, Lord, Simon R., Falk, Stephen, Anthoney, D. Alan, Turkington, Richard C., Goff, Matthew, Elhussein, Leena, Collins, Linda, Love, Sharon, Moschandreas, Joanna, Middleton, Mark R.
Publicado 2020