Association between white matter hyperintensity load and grey matter atrophy in mild cognitive impairment is not unidirectional

por Vipin, Ashwati, Wong, Benjamin Yi Xin, Kumar, Dilip, Low, Audrey, Ng, Kok Pin, Kandiah, Nagaendran
Publicado 2021

Targeting Translation Termination Machinery with Antisense Oligonucleotides for Diseases Caused by Nonsense Mutations

por Huang, Lulu, Aghajan, Mariam, Quesenberry, Tianna, Low, Audrey, Murray, Susan F., Monia, Brett P., Guo, Shuling
Publicado 2019

Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations

por Huang, Lulu, Low, Audrey, Damle, Sagar S., Keenan, Melissa M., Kuntz, Steven, Murray, Susan F., Monia, Brett P., Guo, Shuling
Publicado 2018

Serious infection risk after 1 year between patients with rheumatoid arthritis treated with rituximab or with a second TNFi after initial TNFi failure: results from The British Soc...

por Silva-Fernández, Lucía, De Cock, Diederik, Lunt, Mark, Low, Audrey S, Watson, Kath D, Symmons, Deborah P M, Hyrich, Kimme L
Publicado 2018

Fluid-attenuated inversion recovery magnetic resonance imaging textural features as sensitive markers of white matter damage in midlife adults

por Dounavi, Maria-Eleni, Low, Audrey, Muniz-Terrera, Graciela, Ritchie, Karen, Ritchie, Craig W., Su, Li, Markus, Hugh S., O’Brien, John T.
Publicado 2022

Risk of solid cancer in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

por Mercer, Louise K, Lunt, Mark, Low, Audrey L S, Dixon, William G, Watson, Kath D, Symmons, Deborah P M, Hyrich, Kimme L
Publicado 2015

Association Between Ischemic Stroke and Tumor Necrosis Factor Inhibitor Therapy in Patients With Rheumatoid Arthritis

por Low, Audrey S. L., Lunt, Mark, Mercer, Louise K., Watson, Kath D., Dixon, William G., Symmons, Deborah P. M., Hyrich, Kimme L.
Publicado 2016

Peak Width of Skeletonized Mean Diffusivity as a Marker of Diffuse Cerebrovascular Damage

por Low, Audrey, Mak, Elijah, Stefaniak, James D., Malpetti, Maura, Nicastro, Nicolas, Savulich, George, Chouliaras, Leonidas, Markus, Hugh S., Rowe, James B., O’Brien, John T.
Publicado 2020

Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis

por Low, Audrey S L, Symmons, Deborah P M, Lunt, Mark, Mercer, Louise K, Gale, Chris P, Watson, Kath D, Dixon, William G, Hyrich, Kimme L
Publicado 2017

Evidence of cerebral hemodynamic dysregulation in middle-aged APOE ε4 carriers: The PREVENT-Dementia study

por Dounavi, Maria-Eleni, Low, Audrey, McKiernan, Elizabeth F, Mak, Elijah, Muniz-Terrera, Graciela, Ritchie, Karen, Ritchie, Craig W, Su, Li, O’Brien, John T.
Publicado 2021

Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice

por Casu, Carla, Liu, Alison, De Rosa, Gianluca, Low, Audrey, Suzuki, Aae, Sinha, Sayantani, Ginzburg, Yelena Z., Abrams, Charles, Aghajan, Mariam, Guo, Shuling, Rivella, Stefano
Publicado 2021

Risk of cancer in patients receiving non-biologic disease-modifying therapy for rheumatoid arthritis compared with the UK general population

por Mercer, Louise K., Davies, Rebecca, Galloway, James B., Low, Audrey, Lunt, Mark, Dixon, William G., Watson, Kath D., Symmons, Deborah P. M., Hyrich, Kimme L.
Publicado 2013

Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study

por Low, Audrey, Su, Li, Stefaniak, James D., Mak, Elijah, Dounavi, Maria-Eleni, Muniz-Terrera, Graciela, Ritchie, Karen, Ritchie, Craig W., Markus, Hugh S., O'Brien, John T.
Publicado 2021

Risk of lymphoma in patients exposed to antitumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

por Mercer, Louise K, Galloway, James B, Lunt, Mark, Davies, Rebecca, Low, Audrey L S, Dixon, William G, Watson, Kath D, Symmons, Deborah P M, Hyrich, Kimme L
Publicado 2017

Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor

por Schmidt, Karsten, Prakash, Thazha P., Donner, Aaron J., Kinberger, Garth A., Gaus, Hans J., Low, Audrey, Østergaard, Michael E., Bell, Melanie, Swayze, Eric E., Seth, Punit P.
Publicado 2017

In vivo neuroinflammation and cerebral small vessel disease in mild cognitive impairment and Alzheimer’s disease

por Low, Audrey, Mak, Elijah, Malpetti, Maura, Passamonti, Luca, Nicastro, Nicolas, Stefaniak, James D, Savulich, George, Chouliaras, Leonidas, Su, Li, Rowe, James B, Markus, Hugh S, O'Brien, John T
Publicado 2021

Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

por Prakash, Thazha P, Mullick, Adam E, Lee, Richard G, Yu, Jinghua, Yeh, Steve T, Low, Audrey, Chappell, Alfred E, Østergaard, Michael E, Murray, Sue, Gaus, Hans J, Swayze, Eric E, Seth, Punit P
Publicado 2019

Understanding the effect of controlling phosphorothioate chirality in the DNA gap on the potency and safety of gapmer antisense oligonucleotides

por Østergaard, Michael E, De Hoyos, Cheryl L, Wan, W Brad, Shen, Wen, Low, Audrey, Berdeja, Andres, Vasquez, Guillermo, Murray, Susan, Migawa, Michael T, Liang, Xue-hai, Swayze, Eric E, Crooke, Stanley T, Seth, Punit P
Publicado 2020

Asymmetrical atrophy of thalamic subnuclei in Alzheimer's disease and amyloid-positive mild cognitive impairment is associated with key clinical features

por Low, Audrey, Mak, Elijah, Malpetti, Maura, Chouliaras, Leonidas, Nicastro, Nicolas, Su, Li, Holland, Negin, Rittman, Timothy, Rodríguez, Patricia Vázquez, Passamonti, Luca, Bevan-Jones, W Richard, Jones, PP Simon, Rowe, James B., O'Brien, John T.
Publicado 2019

Site-specific incorporation of 5′-methyl DNA enhances the therapeutic profile of gapmer ASOs

por Vasquez, Guillermo, Freestone, Graeme C, Wan, W Brad, Low, Audrey, De Hoyos, Cheryl Li, Yu, Jinghua, Prakash, Thazha P, Ǿstergaard, Michael E, Liang, Xue-hai, Crooke, Stanley T, Swayze, Eric E, Migawa, Michael T, Seth, Punit P
Publicado 2021