Gene expression profiling reveals a possible role for somatostatin in the innate immune response of the liver

por Adams, Jessica M., Low, Malcolm J.
Publicado 2015

Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes

por Yu, Hui, Rubinstein, Marcelo, Low, Malcolm J
Publicado 2022

SAT-299 Chronic Treatment Of Juvenile Hypothalamic Pomc-deficient Mice With RM-493 Prevents The Development Of Obesity

por Thompson, Zoe, Shah, Bhavik P, Low, Malcolm J
Publicado 2020

Glucose Rapidly Induces Different Forms of Excitatory Synaptic Plasticity in Hypothalamic POMC Neurons

por Hu, Jun, Jiang, Lin, Low, Malcolm J., Rui, Liangyou
Publicado 2014

Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency

por Surbhi, Wittmann, Gábor, Low, Malcolm J., Lechan, Ronald M.
Publicado 2021

OR16-03 Metabolic Effects Of Hypothalamic Pomc Neurons Generated Postnatally From Tanycytes On A Pomc Null Genetic Background

por Gahlot, Surbhi, Wittmann, Gabor, Lechan, Ronald M, Low, Malcolm J
Publicado 2020

Unraveling the Central Proopiomelanocortin Neural Circuits

por Mercer, Aaron J., Hentges, Shane T., Meshul, Charles K., Low, Malcolm J.
Publicado 2013

Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can’t beat them, join them

por Franchini, Lucia F., de Souza, Flavio S.J., Low, Malcolm J., Rubinstein, Marcelo
Publicado 2012

The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight

por Hael, Clara E., Rojo, Daniela, Orquera, Daniela P., Low, Malcolm J., Rubinstein, Marcelo
Publicado 2020

Decreased sensitivity to the anorectic effects of leptin in mice that lack a Pomc-specific neural enhancer

por Na, Elisa S., Lam, Daniel D., Yokosawa, Eva, Adams, Jessica M., Olson, David P., Low, Malcolm J.
Publicado 2020

Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice

por Chhabra, Kavaljit H., Morgan, Donald A., Tooke, Benjamin P., Adams, Jessica M., Rahmouni, Kamal, Low, Malcolm J.
Publicado 2017

Hypothalamic POMC deficiency increases circulating adiponectin despite obesity

por Yu, Hui, Chhabra, Kavaljit H., Thompson, Zoe, Jones, Graham L., Kiran, Sylee, Shangguan, Gary, Low, Malcolm J.
Publicado 2020

Ancient Exaptation of a CORE-SINE Retroposon into a Highly Conserved Mammalian Neuronal Enhancer of the Proopiomelanocortin Gene

por Santangelo, Andrea M, de Souza, Flávio S. J, Franchini, Lucía F, Bumaschny, Viviana F, Low, Malcolm J, Rubinstein, Marcelo
Publicado 2007

Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria

por Chhabra, Kavaljit H., Adams, Jessica M., Fagel, Brian, Lam, Daniel D., Qi, Nathan, Rubinstein, Marcelo, Low, Malcolm J.
Publicado 2016

Selective Restoration of Pomc Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network

por Jones, Graham L., Wittmann, Gábor, Yokosawa, Eva B., Yu, Hui, Mercer, Aaron J., Lechan, Ronald M., Low, Malcolm J.
Publicado 2019

Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity

por Chhabra, Kavaljit H., Adams, Jessica M., Jones, Graham L., Yamashita, Miho, Schlapschy, Martin, Skerra, Arne, Rubinstein, Marcelo, Low, Malcolm J.
Publicado 2016

Electrical stimulation of renal nerves for modulating urine glucose excretion in rats

por Jiman, Ahmad A., Chhabra, Kavaljit H., Lewis, Alfor G., Cederna, Paul S., Seeley, Randy J., Low, Malcolm J., Bruns, Tim M.
Publicado 2018

Not All Mice Are the Same: Standardization of Animal Research Data Presentation

por Omary, M. Bishr, Cohen, David E., El-Omar, Emad M., Jalan, Rajiv, Low, Malcolm J., Nathanson, Michael H., Peek, Richard M., Turner, Jerrold R.
Publicado 2016

Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice

por Tooke, Benjamin P., Yu, Hui, Adams, Jessica M., Jones, Graham L., Sutton-Kennedy, Talisha, Mundada, Lakshmi, Qi, Nathan R., Low, Malcolm J., Chhabra, Kavaljit H.
Publicado 2018

5-HT Obesity Medication Efficacy via POMC Activation is Maintained During Aging

por Burke, Luke K., Doslikova, Barbora, D'Agostino, Giuseppe, Garfield, Alastair S., Farooq, Gala, Burdakov, Denis, Low, Malcolm J., Rubinstein, Marcelo, Evans, Mark L., Billups, Brian, Heisler, Lora K.
Publicado 2014