Evidence for different mechanisms of ‘unhooking’ for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples

por Spanswick, Victoria J, Lowe, Helen L, Newton, Claire, Bingham, John P, Bagnobianchi, Alessia, Kiakos, Konstantinos, Craddock, Charles, Ledermann, Jonathan A, Hochhauser, Daniel, Hartley, John A
Publicado 2012

A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer

por Ohnmacht, Stephan A, Marchetti, Chiara, Gunaratnam, Mekala, Besser, Rachael J, Haider, Shozeb M, Di Vita, Gloria, Lowe, Helen L, Mellinas-Gomez, Maria, Diocou, Seckou, Robson, Mathew, Šponer, Jiri, Islam, Barira, Barbara Pedley, R, Hartley, John A, Neidle, Stephen
Publicado 2015

PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer

por Propper, David J., Gao, Fangfei, Saunders, Mark P., Sarker, Debashis, Hartley, John A., Spanswick, Victoria J., Lowe, Helen L., Hackett, Louise D., Ng, Tony T., Barber, Paul R., Weitsman, Gregory E., Pearce, Sarah, White, Laura, Lopes, Andre, Forsyth, Sharon, Hochhauser, Daniel
Publicado 2022

VEROnA Protocol: A Pilot, Open-Label, Single-Arm, Phase 0, Window-of-Opportunity Study of Vandetanib-Eluting Radiopaque Embolic Beads (BTG-002814) in Patients With Resectable Liver...

por Beaton, Laura, Tregidgo, Henry F J, Znati, Sami A, Forsyth, Sharon, Clarkson, Matthew J, Bandula, Steven, Chouhan, Manil, Lowe, Helen L, Zaw Thin, May, Hague, Julian, Sharma, Dinesh, Pollok, Joerg-Matthias, Davidson, Brian R, Raja, Jowad, Munneke, Graham, Stuckey, Daniel J, Bascal, Zainab A, Wilde, Paul E, Cooper, Sarah, Ryan, Samantha, Czuczman, Peter, Boucher, Eveline, Hartley, John A, Lewis, Andrew L, Jansen, Marnix, Meyer, Tim, Sharma, Ricky A
Publicado 2019

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution

por Abbosh, Christopher, Birkbak, Nicolai J., Wilson, Gareth A., Jamal-Hanjani, Mariam, Constantin, Tudor, Salari, Raheleh, Le Quesne, John, Moore, David A, Veeriah, Selvaraju, Rosenthal, Rachel, Marafioti, Teresa, Kirkizlar, Eser, Watkins, Thomas B K, McGranahan, Nicholas, Ward, Sophia, Martinson, Luke, Riley, Joan, Fraioli, Francesco, Al Bakir, Maise, Grönroos, Eva, Zambrana, Francisco, Endozo, Raymondo, Bi, Wenya Linda, Fennessy, Fiona M., Sponer, Nicole, Johnson, Diana, Laycock, Joanne, Shafi, Seema, Czyzewska-Khan, Justyna, Rowan, Andrew, Chambers, Tim, Matthews, Nik, Turajlic, Samra, Hiley, Crispin, Lee, Siow Ming, Forster, Martin D., Ahmad, Tanya, Falzon, Mary, Borg, Elaine, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M, Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Summers, Yvonne, Hafez, Dina, Naik, Ashwini, Ganguly, Apratim, Kareht, Stephanie, Shah, Rajesh, Joseph, Leena, Quinn, Anne Marie, Crosbie, Phil, Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean, Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-sellers, Melanie, Prakash, Vineet, Lester, Jason, Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Davies, Helen, Oukrif, Dahmane, Akarca, Ayse U, Hartley, John A, Lowe, Helen L, Lock, Sara, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Elgar, Greg, Szallasi, Zoltan, Schwarz, Roland F, Herrero, Javier, Stewart, Aengus, Quezada, Sergio A, Peggs, Karl S., Van Loo, Peter, Dive, Caroline, Lin, Jimmy, Rabinowitz, Matthew, Aerts, Hugo JWL, Hackshaw, Allan, Shaw, Jacqui A, Zimmermann, Bernhard G., Swanton, Charles
Publicado 2017