Mutant p53: it’s not all one and the same

por Kennedy, Margaret C., Lowe, Scott W.
Publicado 2022

p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

por Iannello, Alexandre, Thompson, Thornton W., Ardolino, Michele, Lowe, Scott W., Raulet, David H.
Publicado 2013

Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome

por Romesser, Paul B., Kim, Amanda S., Jeong, Jeho, Mayle, Allison, Dow, Lukas E., Lowe, Scott W.
Publicado 2019

scKINETICS: inference of regulatory velocity with single-cell transcriptomics data

por Burdziak, Cassandra, Zhao, Chujun Julia, Haviv, Doron, Alonso-Curbelo, Direna, Lowe, Scott W, Pe’er, Dana
Publicado 2023

A Pipeline for Drug Target Identification and Validation

por Manchado, Eusebio, Huang, Chun-Hao, Tasdemir, Nilgun, Tschaharganeh, Darjus F., Wilkinson, John E., Lowe, Scott W.
Publicado 2017

Arid1a restrains Kras-dependent changes in acinar cell identity

por Livshits, Geulah, Alonso-Curbelo, Direna, Morris, John P, Koche, Richard, Saborowski, Michael, Wilkinson, John Erby, Lowe, Scott W
Publicado 2018

A modular and flexible ESC-based mouse model of pancreatic cancer

por Saborowski, Michael, Saborowski, Anna, Morris, John P., Bosbach, Benedikt, Dow, Lukas E., Pelletier, Jerry, Klimstra, David S., Lowe, Scott W.
Publicado 2014

A common functional consequence of tumor-derived mutations within c-MYC

por Chakraborty, Abhishek A., Scuoppo, Claudio, Dey, Soumyadeep, Thomas, Lance R., Lorey, Shelly L., Lowe, Scott W., Tansey, William. P.
Publicado 2014

Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice

por Dow, Lukas E., Nasr, Zeina, Saborowski, Michael, Ebbesen, Saya H., Manchado, Eusebio, Tasdemir, Nilgun, Lee, Teresa, Pelletier, Jerry, Lowe, Scott W.
Publicado 2014

Direct and indirect targeting of MYC to treat acute myeloid leukemia

por Brondfield, Sam, Umesh, Sushma, Corella, Alexandra, Zuber, Johannes, Rappaport, Amy R., Gaillard, Coline, Lowe, Scott W., Goga, Andrei, Kogan, Scott C.
Publicado 2015

High resolution copy number inference in cancer using short-molecule nanopore sequencing

por Baslan, Timour, Kovaka, Sam, Sedlazeck, Fritz J, Zhang, Yanming, Wappel, Robert, Tian, Sha, Lowe, Scott W, Goodwin, Sara, Schatz, Michael C
Publicado 2021

Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition

por Bolden, Jessica E., Tasdemir, Nilgun, Dow, Lukas E., van Es, Johan H., Wilkinson, John E., Zhao, Zhen, Clevers, Hans, Lowe, Scott W.
Publicado 2014

Longitudinal Multiplexed Measurement of Quantitative Proteomic Signatures in Mouse Lymphoma Models Using Magneto-Nanosensors

por Lee, Jung-Rok, Appelmann, Iris, Miething, Cornelius, Shultz, Tyler O., Ruderman, Daniel, Kim, Dokyoon, Mallick, Parag, Lowe, Scott W., Wang, Shan X.
Publicado 2018

Chelator-Free Radiolabeling of SERRS Nanoparticles for Whole-Body PET and Intraoperative Raman Imaging

por Wall, Matthew A., Shaffer, Travis M., Harmsen, Stefan, Tschaharganeh, Darjus-Felix, Huang, Chun-Hao, Lowe, Scott W., Drain, Charles Michael, Kircher, Moritz F.
Publicado 2017

Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition

por Chen, Chong, Liu, Yu, Lu, Chao, Cross, Justin R., Morris, John P., Shroff, Aditya S., Ward, Patrick S., Bradner, James E., Thompson, Craig, Lowe, Scott W.
Publicado 2013

Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopecia

por Nasr, Zeina, Dow, Lukas E, Paquet, Marilene, Chu, Jennifer, Ravindar, Kontham, Somaiah, Ragam, Deslongchamps, Pierre, Porco Jr, John A, Lowe, Scott W, Pelletier, Jerry
Publicado 2013

Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice

por Takiguchi, Megumi, Dow, Lukas E., Prier, Julia E., Carmichael, Catherine L., Kile, Benjamin T., Turner, Stephen J., Lowe, Scott W., Huang, David C. S., Dickins, Ross A.
Publicado 2013

Inducible in vivo genome editing with CRISPR/Cas9

por Dow, Lukas E, Fisher, Jonathan, O'Rourke, Kevin P, Muley, Ashlesha, Kastenhuber, Edward R, Livshits, Geulah, Tschaharganeh, Darjus F, Socci, Nicholas D, Lowe, Scott W
Publicado 2015

Reversible Suppression of Cyclooxygenase 2 (COX-2) Expression In Vivo by Inducible RNA Interference

por Zaiss, Anne K., Zuber, Johannes, Chu, Chun, Machado, Hidevaldo B., Jiao, Jing, Catapang, Arthur B., Ishikawa, Tomo-o, Gil, Jose S., Lowe, Scott W., Herschman, Harvey R.
Publicado 2014

TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions

por Shirole, Nitin H, Pal, Debjani, Kastenhuber, Edward R, Senturk, Serif, Boroda, Joseph, Pisterzi, Paola, Miller, Madison, Munoz, Gustavo, Anderluh, Marko, Ladanyi, Marc, Lowe, Scott W, Sordella, Raffaella
Publicado 2016