Splicing factor SF3B1(K700E) mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1

por Jin, Shuiling, Su, Hairui, Tran, Ngoc-Tung, Song, Jing, Lu, Sydney S., Li, Ying, Huang, Suming, Abdel-Wahab, Omar, Liu, Yanyan, Zhao, Xinyang
Publicado 2017

Waldenström macroglobulinemia whole genome reveals prolonged germinal center activity and late copy number aberrations

por Maclachlan, Kylee H., Bagratuni, Tina, Kastritis, Efstathios, Ziccheddu, Bachisio, Lu, Sydney, Yellapantula, Venkata, Famulare, Chris, Argyropoulos, Kimon, Derkach, Andriy, Papaemmanuil, Elli, Dogan, Ahmet, Lesokhin, Alexander, Usmani, Saad Z., Landgren, C. Ola, Palomba, Lia M., Maura, Francesco, Dimopoulos, Meletios A.
Publicado 2022

E7820, an anti-cancer sulfonamide, degrades RBM39 in patients with splicing factor mutant myeloid malignancies: a phase II clinical trial

por Bewersdorf, Jan Philipp, Stahl, Maximilian, Taylor, Justin, Mi, Xiaoli, Chandhok, Namrata Sonia, Watts, Justin, Derkach, Andriy, Wysocki, Mateusz, Lu, Sydney X., Bourcier, Jessie, Hogg, Simon J., Rahman, Jahan, Chaudhry, Sana, Totiger, Tulasigeri M., Abdel-Wahab, Omar, Stein, Eytan M.
Publicado 2023

NOD2 regulates hematopoietic cell function during graft-versus-host disease

por Penack, Olaf, Smith, Odette M., Cunningham-Bussel, Amy, Liu, Xin, Rao, Uttam, Yim, Nury, Na, Il-Kang, Holland, Amanda M., Ghosh, Arnab, Lu, Sydney X., Jenq, Robert R., Liu, Chen, Murphy, George F., Brandl, Katharina, van den Brink, Marcel R.M.
Publicado 2009

Spliceosomal disruption of the non-canonical BAF complex in cancer

por Inoue, Daichi, Chew, Guo-Liang, Liu, Bo, Michel, Brittany C., Pangallo, Joseph, D’Avino, Andrew R., Hitchman, Tyler, North, Khrystyna, Lee, Stanley Chun-Wei, Bitner, Lillian, Block, Ariele, Moore, Amanda R., Yoshimi, Akihide, Escobar-Hoyos, Luisa, Cho, Hana, Penson, Alex, Lu, Sydney X., Taylor, Justin, Chen, Yu, Kadoch, Cigall, Abdel-Wahab, Omar, Bradley, Robert K.
Publicado 2019

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL

por Pastore, Alessandro, Gaiti, Federico, Lu, Sydney X., Brand, Ryan M., Kulm, Scott, Chaligne, Ronan, Gu, Hongcang, Huang, Kevin Y., Stamenova, Elena K., Béguelin, Wendy, Jiang, Yanwen, Schulman, Rafael C., Kim, Kyu-Tae, Alonso, Alicia, Allan, John N., Furman, Richard R., Gnirke, Andreas, Wu, Catherine J., Melnick, Ari M., Meissner, Alexander, Bernstein, Bradley E., Abdel-Wahab, Omar, Landau, Dan A.
Publicado 2019

COVID-19 infections and outcomes in patients with multiple myeloma in New York City: a cohort study from five academic centers

por Hultcrantz, Malin, Richter, Joshua, Rosenbaum, Cara, Patel, Dhwani, Smith, Eric, Korde, Neha, Lu, Sydney, Mailankody, Sham, Shah, Urvi, Lesokhin, Alexander, Hassoun, Hani, Tan, Carlyn, Maura, Francesco, Derkacs, Andriy, Diamond, Benjamin, Rossi, Adriana, Pearse, Roger N., Madduri, Deepu, Chari, Ajai, Kaminetsky, David, Braunstein, Marc, Gordillo, Christian, Davies, Faith, Jagannath, Sundar, Niesvizky, Ruben, Lentzsch, Suzanne, Morgan, Gareth, Landgren, Ola
Publicado 2020

Tailored treatment to MRD response: A phase I/II study for newly diagnosed multiple myeloma patients using high dose twice‐weekly carfilzomib (45 and 56 mg/m(2)) in combination wit...

por Korde, Neha, Mastey, Donna, Tavitian, Elizabet, Mailankody, Sham, Lesokhin, Alexander, Hassoun, Hani, Smith, Eric L., Lendvai, Nikoletta, Hultcrantz, Malin, Shah, Urvi, Tan, Carlyn, Lu, Sydney, Diamond, Benjamin, Salcedo, Meghan, Werner, Kelly, Chung, David J., Scordo, Michael, Shah, Gunjan L., Lahoud, Oscar, Landau, Heather, Arcila, Maria, Ho, Caleb, Roshal, Mikhail, Dogan, Ahmet, Derkach, Andriy, Devlin, Sean M., Giralt, Sergio A., Landgren, Ola
Publicado 2021

Ceacam1 Separates Graft-versus-Host-Disease from Graft-versus-Tumor Activity after Experimental Allogeneic Bone Marrow Transplantation

por Lu, Sydney X., Kappel, Lucy W., Charbonneau-Allard, Anne-Marie, Atallah, Renée, Holland, Amanda M., Turbide, Claire, Hubbard, Vanessa M., Rotolo, Jimmy A., Smith, Marsinay, Suh, David, King, Christopher, Rao, Uttam K., Yim, Nury, Bautista, Johanne L., Jenq, Robert R., Penack, Olaf, Na, Il-Kang, Liu, Chen, Murphy, George, Alpdogan, Onder, Blumberg, Richard S., Macian, Fernando, Holmes, Kathryn V., Beauchemin, Nicole, van den Brink, Marcel R. M.
Publicado 2011

Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

por Inoue, Daichi, Polaski, Jacob T., Taylor, Justin, Castel, Pau, Chen, Sisi, Kobayashi, Susumu, Hogg, Simon J., Hayashi, Yasutaka, Pineda, Jose Mario Bello, El Marabti, Ettaib, Erickson, Caroline, Knorr, Katherine, Fukumoto, Miki, Yamazaki, Hiromi, Tanaka, Atsushi, Fukui, Chie, Lu, Sydney X., Durham, Benjamin H., Liu, Bo, Wang, Eric, Mehta, Sanjoy, Zakheim, Daniel, Garippa, Ralph, Penson, Alex, Chew, Guo-Liang, McCormick, Frank, Bradley, Robert K., Abdel-Wahab, Omar
Publicado 2021

COVID-19 Infections and Clinical Outcomes in Patients with Multiple Myeloma in New York City: A Cohort Study from Five Academic Centers

por Hultcrantz, Malin, Richter, Joshua, Rosenbaum, Cara A., Patel, Dhwani, Smith, Eric L., Korde, Neha, Lu, Sydney X., Mailankody, Sham, Shah, Urvi A., Lesokhin, Alexander M., Hassoun, Hani, Tan, Carlyn, Maura, Francesco, Derkach, Andriy, Diamond, Benjamin, Rossi, Adriana, Pearse, Roger N., Madduri, Deepu, Chari, Ajai, Kaminetzky, David, Braunstein, Marc J., Gordillo, Christian, Reshef, Ran, Taur, Ying, Davies, Faith E., Jagannath, Sundar, Niesvizky, Ruben, Lentzsch, Suzanne, Morgan, Gareth J., Landgren, Ola
Publicado 2020

Activating mutations in CSF-1R and additional receptor tyrosine kinases in histiocytic neoplasms

por Durham, Benjamin H., Rodrigo, Estibaliz Lopez, Picarsic, Jennifer, Abramson, David, Rotemberg, Veronica, De Munck, Steven, Pannecoucke, Erwin, Lu, Sydney X., Pastore, Alessandro, Yoshimi, Akihide, Mandelker, Diana, Ceyhan-Birsoy, Ozge, Ulaner, Gary A., Walsh, Michael, Yabe, Mariko, Petrova-Drus, Kseniya, Arcila, Maria E., Ladanyi, Marc, Solit, David B., Berger, Michael F., Hyman, David M., Lacouture, Mario E., Erickson, Caroline, Saganty, Ruth, Ki, Michelle, Dunkel, Ira J., López, Vicente Santa-María, Mora, Jaume, Haroche, Julien, Emile, Jean-Francois, Decaux, Olivier, Geissmann, Frederic, Savvides, Savvas N., Drilon, Alexander, Diamond, Eli L., Abdel-Wahab, Omar
Publicado 2019

Accelerated single cell seeding in relapsed multiple myeloma

por Landau, Heather J., Yellapantula, Venkata, Diamond, Benjamin T., Rustad, Even H., Maclachlan, Kylee H., Gundem, Gunes, Medina-Martinez, Juan, Ossa, Juan Arango, Levine, Max F., Zhou, Yangyu, Kappagantula, Rajya, Baez, Priscilla, Attiye, Marc, Makohon-Moore, Alvin, Zhang, Lance, Boyle, Eileen M., Ashby, Cody, Blaney, Patrick, Patel, Minal, Zhang, Yanming, Dogan, Ahmet, Chung, David J., Giralt, Sergio, Lahoud, Oscar B., Peled, Jonathan U., Scordo, Michael, Shah, Gunjan, Hassoun, Hani, Korde, Neha S., Lesokhin, Alexander M., Lu, Sydney, Mailankody, Sham, Shah, Urvi, Smith, Eric, Hultcrantz, Malin L., Ulaner, Gary A., van Rhee, Frits, Morgan, Gareth J., Landgren, Ola, Papaemmanuil, Elli, Iacobuzio-Donahue, Christine, Maura, Francesco
Publicado 2020

Author Correction: Accelerated single cell seeding in relapsed multiple myeloma

por Landau, Heather J., Yellapantula, Venkata, Diamond, Benjamin T., Rustad, Even H., Maclachlan, Kylee H., Gundem, Gunes, Medina-Martinez, Juan, Ossa, Juan Arango, Levine, Max F., Zhou, Yangyu, Kappagantula, Rajya, Baez, Priscilla, Attiyeh, Marc, Makohon-Moore, Alvin, Zhang, Lance, Boyle, Eileen M., Ashby, Cody, Blaney, Patrick, Patel, Minal, Zhang, Yanming, Dogan, Ahmet, Chung, David J., Giralt, Sergio, Lahoud, Oscar B., Peled, Jonathan U., Scordo, Michael, Shah, Gunjan, Hassoun, Hani, Korde, Neha S., Lesokhin, Alexander M., Lu, Sydney, Mailankody, Sham, Shah, Urvi, Smith, Eric, Hultcrantz, Malin L., Ulaner, Gary A., van Rhee, Frits, Morgan, Gareth J., Landgren, Ola, Papaemmanuil, Elli, Iacobuzio-Donahue, Christine, Maura, Francesco
Publicado 2021