Major hurdles to the use of tyrosine kinase inhibitors in clinical prevention/interception studies: Do preclinical studies with EGFR inhibitors suggest approaches to overcome some...

por Dragnev, Konstantin H., Dragnev, Christo P. C., Lubet, Ronald A.
Publicado 2023

Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism

por Shilkaitis, Anne, Green, Albert, Punj, Vasu, Steele, Vernon, Lubet, Ronald, Christov, Konstantin
Publicado 2005

Chemopreventive effects of celecoxib are limited to hormonally responsive mammary carcinomas in the neu-induced retroviral rat model

por Woditschka, Stephan, Haag, Jill D, Mau, Bob, Lubet, Ronald A, Gould, Michael N
Publicado 2008

Pharmacometabolomic Pathway Response of Effective Anticancer Agents on Different Diets in Rats with Induced Mammary Tumors

por Cao, Zhijun, Miller, Mark Steven, Lubet, Ronald A., Grubbs, Clinton J., Beger, Richard D.
Publicado 2019

Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine

por Pan, Jing, Zhang, Qi, Sei, Shizuko, Shoemaker, Robert H., Lubet, Ronald A., Wang, Yian, You, Ming
Publicado 2017

Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKT inhibitor MK2206 in mammary cancer models

por Lubet, Ronald A., Steele, Vernon E., Juliana, M.M., Bode, Ann, Moeinpour, Fariba, Grubbs, Clinton J.
Publicado 2018

Daily or weekly dosing with EGFR inhibitors, gefitinib and lapatinib, and AKT inhibitor MK2206 in mammary cancer models

por Lubet, Ronald A., Steele, Vernon E., Juliana, M.M., Bode, Ann, Moeinpour, Fariba, Grubbs, Clinton J.
Publicado 2019

Novel mutational landscapes and expression signatures of lung squamous cell carcinoma

por Xiong, Donghai, Pan, Jing, Yin, Yuxin, Jiang, Hui, Szabo, Eva, Lubet, Ronald A., Wang, Yian, You, Ming
Publicado 2017

Transforming growth factors-β are not good biomarkers of chemopreventive efficacy in a preclinical breast cancer model system

por Zujewski, JoAnne, Vaughn-Cooke, Anika, Flanders, Kathleen C, Eckhaus, Michael A, Lubet, Ronald A, Wakefield, Lalage M
Publicado 2001

Suppression of Rat Oral Carcinogenesis by Agonists of Peroxisome Proliferator Activated Receptor γ

por McCormick, David L., Horn, Thomas L., Johnson, William D., Peng, Xinjian, Lubet, Ronald A., Steele, Vernon E.
Publicado 2015

Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents

por Xiong, Donghai, Pan, Jing, Zhang, Qi, Szabo, Eva, Miller, Mark Steven, Lubet, Ronald A., You, Ming, Wang, Yian
Publicado 2016

Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma

por Pan, Jing, Xiong, Donghai, Zhang, Qi, Szabo, Eva, Miller, Mark Steven, Lubet, Ronald A., Wang, Yian, You, Ming
Publicado 2018

Effects of High-Fructose Diet vs. Teklad Diet in the MNU-Induced Rat Mammary Cancer Model: Altered Tumorigenesis, Metabolomics and Tumor RNA Expression

por Kumar, Amit, Lubet, Ronald A., Fox, Jennifer T., Nelson, William G., Seifried, Harold, Grubbs, Clinton J., Miller, Mark Steven
Publicado 2021

Exosomal miRNAs as Novel Pharmacodynamic Biomarkers for Cancer Chemopreventive Agent Early Stage Treatments in Chemically Induced Mouse Model of Lung Squamous Cell Carcinoma

por Zhou, Yu, Zhang, Qi, Du, Meijun, Xiong, Donghai, Wang, Yian, Mohammed, Altaf, Lubet, Ronald A., Wang, Liang, You, Ming
Publicado 2019

Prediction of Molecular Targets of Cancer Preventing Flavonoid Compounds Using Computational Methods

por Chen, Hanyong, Yao, Ke, Nadas, Janos, Bode, Ann M., Malakhova, Margarita, Oi, Naomi, Li, Haitao, Lubet, Ronald A., Dong, Zigang
Publicado 2012

Select Dietary Phytochemicals Function as Inhibitors of COX-1 but Not COX-2

por Li, Haitao, Zhu, Feng, Sun, Yanwen, Li, Bing, Oi, Naomi, Chen, Hanyong, Lubet, Ronald A., Bode, Ann M., Dong, Zigang
Publicado 2013

Multi-Epitope-Based Vaccines for Colon Cancer Treatment and Prevention

por Corulli, Lauren R., Cecil, Denise L., Gad, Ekram, Koehnlein, Marlese, Coveler, Andrew L., Childs, Jennifer S., Lubet, Ronald A., Disis, Mary L.
Publicado 2021

Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer

por Thompson, Matthew D., Lubet, Ronald A., Mccormick, David L., Clapper, Margie L., Bode, Ann M., Juliana, M. Margaret, Moeinpour, Fariba, Grubbs, Clinton J.
Publicado 2017

Potentiation of Kras peptide cancer vaccine by avasimibe, a cholesterol modulator

por Pan, Jing, Zhang, Qi, Palen, Katie, Wang, Li, Qiao, Lifen, Johnson, Bryon, Sei, Shizuko, Shoemaker, Robert H., Lubet, Ronald A., Wang, Yian, You, Ming
Publicado 2019

Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR‐Driven Lung Cancer

por Huang, Mofei, Xiong, Donghai, Pan, Jing, Zhang, Qi, Sei, Shizuko, Shoemaker, Robert H., Lubet, Ronald A., Montuenga, Luis M., Wang, Yian, Slusher, Barbara S., You, Ming
Publicado 2022