Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid‐dependent, human immunodeficiency virus seronegative participants

por Moore, Katy, Magee, Mindy, Sevinsky, Heather, Chang, Ming, Lubin, Susan, Myers, Elsa, Ackerman, Peter, Llamoso, Cyril
Publicado 2019

Pharmacokinetics of Temsavir, the Active Moiety of the HIV-1 Attachment Inhibitor Prodrug, Fostemsavir, Coadministered with Cobicistat, Etravirine, Darunavir/Cobicistat, or Darunav...

por Moore, Katy, Thakkar, Nilay, Magee, Mindy, Sevinsky, Heather, Vakkalagadda, Blisse, Lubin, Susan, Llamoso, Cyril, Ackerman, Peter
Publicado 2022

Single-Dose Pharmacokinetics of Milvexian in Participants with Normal Renal Function and Participants with Moderate or Severe Renal Impairment

por Perera, Vidya, Abelian, Grigor, Li, Danshi, Wang, Zhaoqing, Zhang, Liping, Lubin, Susan, Bello, Akintunde, Murthy, Bindu
Publicado 2022

Single-Dose Pharmacokinetics of Milvexian in Participants with Mild or Moderate Hepatic Impairment Compared with Healthy Participants

por Perera, Vidya, Abelian, Grigor, Li, Danshi, Wang, Zhaoqing, Zhang, Liping, Lubin, Susan, Chen, Wei, Bello, Akintunde, Murthy, Bindu
Publicado 2022

Pharmacokinetics of Temsavir, the Active Moiety of the Prodrug Fostemsavir, in Subjects with Hepatic Impairment

por Sevinsky, Heather, Magee, Mindy, Ackerman, Peter, Adamczyk, Robert, Karkas, Jennifer, Lubin, Susan, Ravindran, Palanikumar, Llamoso, Cyril, Eley, Timothy, Moore, Katy
Publicado 2017

Effects of Itraconazole and Diltiazem on the Pharmacokinetics and Pharmacodynamics of Milvexian, A Factor XIa Inhibitor

por Perera, Vidya, Wang, Zhaoqing, Lubin, Susan, Christopher, Lisa J., Chen, Wei, Xu, Sophia, Seiffert, Dietmar, DeSouza, Mary, Murthy, Bindu
Publicado 2022

Effects of rifampin on the pharmacokinetics and pharmacodynamics of milvexian, a potent, selective, oral small molecule factor XIa inhibitor

por Perera, Vidya, Wang, Zhaoqing, Lubin, Susan, Christopher, Lisa J., Chen, Wei, Xu, Sophia, Seiffert, Dietmar, DeSouza, Mary, Murthy, Bindu
Publicado 2022

Safety, pharmacokinetics, and pharmacodynamics of milvexian in healthy Japanese participants

por Perera, Vidya, Wang, Zhaoqing, Lubin, Susan, Ueno, Takayo, Shiozaki, Tomomi, Chen, Wei, Xu, Xiaohui, Seiffert, Dietmar, DeSouza, Mary, Murthy, Bindu
Publicado 2022

Use of a cocktail probe to assess potential drug interactions with cytochrome P450 after administration of belatacept, a costimulatory immunomodulator

por Williams, Daphne, Tao, Xiaolu, Zhu, Lili, Stonier, Michele, Lutz, Justin D., Masson, Eric, Zhang, Sean, Ganguly, Bishu, Tzogas, Zoe, Lubin, Susan, Murthy, Bindu
Publicado 2016