Ubiquitin–proteasome system involvement in Huntington’s disease

por Ortega, Zaira, Lucas, Jose J.
Publicado 2014

Neuronal Apoptosis and Motor Deficits in Mice with Genetic Inhibition of GSK-3 Are Fas-Dependent

por Gómez-Sintes, Raquel, Lucas, José J.
Publicado 2013

Altered Levels and Isoforms of Tau and Nuclear Membrane Invaginations in Huntington’s Disease

por Fernández-Nogales, Marta, Lucas, José J.
Publicado 2020

Targeting the proteasome in epilepsy

por Engel, Tobias, Lucas, Jose J., Henshall, David C.
Publicado 2017

GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration

por Gómez-Sintes, Raquel, Hernández, Félix, Lucas, José J., Avila, Jesús
Publicado 2011

P2X7 Receptor Upregulation in Huntington’s Disease Brains

por Ollà, Ivana, Santos-Galindo, María, Elorza, Ainara, Lucas, José J.
Publicado 2020

Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders

por Gómez-Sintes, Raquel, Kvajo, Mirna, Gogos, Joseph A., Lucas, José J.
Publicado 2014

Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease

por Otero, Alicia, Betancor, Marina, Eraña, Hasier, Fernández Borges, Natalia, Lucas, José J., Badiola, Juan José, Castilla, Joaquín, Bolea, Rosa
Publicado 2021

Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin–proteasome system

por McKinnon, Chris, Goold, Rob, Andre, Ralph, Devoy, Anny, Ortega, Zaira, Moonga, Julie, Linehan, Jacqueline M., Brandner, Sebastian, Lucas, José J., Collinge, John, Tabrizi, Sarah J.
Publicado 2015

Pathogenic SREK1 decrease in Huntington’s disease lowers TAF1 mimicking X-linked dystonia parkinsonism

por Hernández, Ivó H, Cabrera, Jorge R, Santos-Galindo, María, Sánchez-Martín, Manuel, Domínguez, Verónica, García-Escudero, Ramón, Pérez-Álvarez, María J, Pintado, Belén, Lucas, José J
Publicado 2020

A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer’s disease

por García-Escudero, Vega, Ruiz-Gabarre, Daniel, Gargini, Ricardo, Pérez, Mar, García, Esther, Cuadros, Raquel, Hernández, Ivó H., Cabrera, Jorge R., García-Escudero, Ramón, Lucas, José J., Hernández, Félix, Ávila, Jesús
Publicado 2021

Huntington’s disease-specific mis-splicing unveils key effector genes and altered splicing factors

por Elorza, Ainara, Márquez, Yamile, Cabrera, Jorge R, Sánchez-Trincado, José Luis, Santos-Galindo, María, Hernández, Ivó H, Picó, Sara, Díaz-Hernández, Juan I, García-Escudero, Ramón, Irimia, Manuel, Lucas, José J
Publicado 2021

Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury

por Engel, Tobias, Martinez-Villarreal, Jaime, Henke, Christine, Jimenez-Mateos, Eva M., Sanz-Rodriguez, Amaya, Alves, Mariana, Hernandez-Santana, Yasmina, Brennan, Gary P., Kenny, Aidan, Campbell, Aoife, Lucas, Jose J., Henshall, David C.
Publicado 2017

Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus

por Engel, Tobias, Gómez-Sintes, Raquel, Alves, Mariana, Jimenez-Mateos, Eva M., Fernández-Nogales, Marta, Sanz-Rodriguez, Amaya, Morgan, James, Beamer, Edward, Rodríguez-Matellán, Alberto, Dunleavy, Mark, Sano, Takanori, Avila, Jesus, Medina, Miguel, Hernandez, Felix, Lucas, José J., Henshall, David C.
Publicado 2018

Huntingtin-mediated axonal transport requires arginine methylation by PRMT6

por Migazzi, Alice, Scaramuzzino, Chiara, Anderson, Eric N., Tripathy, Debasmita, Hernández, Ivó H., Grant, Rogan A., Roccuzzo, Michela, Tosatto, Laura, Virlogeux, Amandine, Zuccato, Chiara, Caricasole, Andrea, Ratovitski, Tamara, Ross, Christopher A., Pandey, Udai B., Lucas, José J., Saudou, Frédéric, Pennuto, Maria, Basso, Manuela
Publicado 2021

Autism-like phenotype and risk gene-RNA deadenylation by CPEB4 mis-splicing

por Parras, Alberto, Anta, Héctor, Santos-Galindo, María, Swarup, Vivek, Elorza, Ainara, Nieto-Gonzalez, José L., Picó, Sara, Hernández, Ivó H., Díaz-Hernández, Juan I., Belloc, Eulàlia, Rodolosse, Annie, Parikshak, Neelroop N., Peñagarikano, Olga, Fernández-Chacón, Rafael, Irimia, Manuel, Navarro, Pilar, Geschwind, Daniel H., Méndez, Raúl, Lucas, José J.
Publicado 2018

CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in huntington’s disease

por Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Publicado 2022

Correction to: CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease

por Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols‑Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas‑Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez‑Pastor, Rocio
Publicado 2022