Single‐cell transcriptomics uncovers an instructive T‐cell receptor role in adult γδ T‐cell lineage commitment

por Scaramuzzino, Sara, Potier, Delphine, Ordioni, Robin, Grenot, Pierre, Payet‐Bornet, Dominique, Luche, Hervé, Malissen, Bernard
Publicado 2022

Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice

por Ricard, Clément, Tchoghandjian, Aurélie, Luche, Hervé, Grenot, Pierre, Figarella-Branger, Dominique, Rougon, Geneviève, Malissen, Marie, Debarbieux, Franck
Publicado 2016

In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis

por Luche, Hervé, Nageswara Rao, Tata, Kumar, Suresh, Tasdogan, Alpaslan, Beckel, Franziska, Blum, Carmen, Martins, Vera C., Rodewald, Hans-Reimer, Fehling, Hans Jörg
Publicado 2013

Diversity of innate immune cell subsets across spatial and temporal scales in an EAE mouse model

por Caravagna, Céline, Jaouën, Alexandre, Desplat-Jégo, Sophie, Fenrich, Keith K., Bergot, Elise, Luche, Hervé, Grenot, Pierre, Rougon, Geneviève, Malissen, Marie, Debarbieux, Franck
Publicado 2018

TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity

por Muto, Go, Kotani, Hitoshi, Kondo, Taisuke, Morita, Rimpei, Tsuruta, Sanae, Kobayashi, Takashi, Luche, Hervé, Fehling, Hans Joerg, Walsh, Matthew, Choi, Yongwon, Yoshimura, Akihiko
Publicado 2013

Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3(+) and Foxp3(−) T cells

por Franckaert, Dean, Dooley, James, Roos, Evelyne, Floess, Stefan, Huehn, Jochen, Luche, Herve, Fehling, Hans Joerg, Liston, Adrian, Linterman, Michelle A, Schlenner, Susan M
Publicado 2015

Multicolor fate mapping of Langerhans cell homeostasis

por Ghigo, Clément, Mondor, Isabelle, Jorquera, Audrey, Nowak, Jonathan, Wienert, Stephan, Zahner, Sonja P., Clausen, Björn E., Luche, Hervé, Malissen, Bernard, Klauschen, Frederick, Bajénoff, Marc
Publicado 2013

Identification of a New Stromal Cell Type Involved in the Regulation of Inflamed B Cell Follicles

por Mionnet, Cyrille, Mondor, Isabelle, Jorquera, Audrey, Loosveld, Marie, Maurizio, Julien, Arcangeli, Marie-Laure, Ruddle, Nancy H., Nowak, Jonathan, Aurrand-Lions, Michel, Luche, Hervé, Bajénoff, Marc
Publicado 2013

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expre...

por Demerlé, Clémence, Gorvel, Laurent, Mello, Marielle, Pastor, Sonia, Degos, Clara, Zarubica, Ana, Angelis, Fabien, Fiore, Frédéric, Nunes, Jacques A, Malissen, Bernard, Greillier, Laurent, Guittard, Geoffrey, Luche, Hervé, Barlesi, Fabrice, Olive, Daniel
Publicado 2023

Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model

por Almosailleakh, Marwa, Bentivegna, Sofia, Narcisi, Samuele, Benquet, Sébasitien J., Gillberg, Linn, Montaño-Almendras, Carmen P., Savickas, Simonas, Schoof, Erwin M., Wegener, Amelie, Luche, Hérve, Jensen, Henrik E., Côme, Christophe, Grønbæk, Kirsten
Publicado 2023

Conditional Deletion of Pdcd1 Identifies the Cell-Intrinsic Action of PD-1 on Functional CD8 T Cell Subsets for Antitumor Efficacy

por Raghavan, Sukanya, Tovbis-Shifrin, Nataliya, Kochel, Christina, Sawant, Anandi, Mello, Marielle, Sathe, Manjiri, Blumenschein, Wendy, Muise, Eric S., Chackerian, Alissa, Pinheiro, Elaine M., Rosahl, Thomas W., Luche, Hervé, de Waal Malefyt, Rene
Publicado 2021

High-throughput mass cytometry staining for deep phenotyping of human natural killer cells

por Ben Amara, Amira, Rouviere, Marie-Sarah, Fattori, Stéphane, Wlosik, Julia, Gregori, Emilie, Boucherit, Nicolas, Bernard, Pierre-Louis, Nunès, Jacques A., Vey, Norbert, Luche, Herve, Gorvel, Laurent, Olive, Daniel, Chretien, Anne-Sophie
Publicado 2022

Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies

por Wendling, Olivia, Champy, Marie-France, Jaubert, Solène, Pavlovic, Guillaume, Dubos, Aline, Lindner, Loic, Jacobs, Hugues, Mark, Manuel, Combe, Roy, Da Cruz, Isabelle Goncalves, Luche, Hervé, Mudgett, John S., Rosahl, Thomas, Sorg, Tania, Malissen, Marie, Reilly, Patrick T., Hérault, Yann
Publicado 2017

LymphoAtlas: a dynamic and integrated phosphoproteomic resource of TCR signaling in primary T cells reveals ITSN2 as a regulator of effector functions

por Locard‐Paulet, Marie, Voisinne, Guillaume, Froment, Carine, Goncalves Menoita, Marisa, Ounoughene, Youcef, Girard, Laura, Gregoire, Claude, Mori, Daiki, Martinez, Manuel, Luche, Hervé, Garin, Jerôme, Malissen, Marie, Burlet‐Schiltz, Odile, Malissen, Bernard, Gonzalez de Peredo, Anne, Roncagalli, Romain
Publicado 2020

In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain

por Cloarec, Robin, Bauer, Sylvian, Teissier, Natacha, Schaller, Fabienne, Luche, Hervé, Courtens, Sandra, Salmi, Manal, Pauly, Vanessa, Bois, Emilie, Pallesi-Pocachard, Emilie, Buhler, Emmanuelle, Michel, François J., Gressens, Pierre, Malissen, Marie, Stamminger, Thomas, Streblow, Daniel N., Bruneau, Nadine, Szepetowski, Pierre
Publicado 2018

Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation

por Cloarec, Robin, Bauer, Sylvian, Luche, Hervé, Buhler, Emmanuelle, Pallesi-Pocachard, Emilie, Salmi, Manal, Courtens, Sandra, Massacrier, Annick, Grenot, Pierre, Teissier, Natacha, Watrin, Françoise, Schaller, Fabienne, Adle-Biassette, Homa, Gressens, Pierre, Malissen, Marie, Stamminger, Thomas, Streblow, Daniel N., Bruneau, Nadine, Szepetowski, Pierre
Publicado 2016

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics

por Voisinne, Guillaume, Kersse, Kristof, Chaoui, Karima, Lu, Liaoxun, Chaix, Julie, Zhang, Lichen, Menoita, Marisa Goncalves, Girard, Laura, Ounoughene, Youcef, Wang, Hui, Burlet-Schiltz, Odile, Luche, Hervé, Fiore, Frédéric, Malissen, Marie, de Peredo, Anne Gonzalez, Liang, Yinming, Roncagalli, Romain, Malissen, Bernard
Publicado 2019

Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia

por Chretien, Anne-Sophie, Fauriat, Cyril, Orlanducci, Florence, Galseran, Claire, Rey, Jerome, Bouvier Borg, Gaelle, Gautherot, Emmanuel, Granjeaud, Samuel, Hamel-Broza, Jean-François, Demerle, Clemence, Ifrah, Norbert, Lacombe, Catherine, Cornillet-Lefebvre, Pascale, Delaunay, Jacques, Toubert, Antoine, Gregori, Emilie, Luche, Herve, Malissen, Marie, Arnoulet, Christine, Nunes, Jacques A., Vey, Norbert, Olive, Daniel
Publicado 2017

High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome

por Chretien, Anne-Sophie, Devillier, Raynier, Granjeaud, Samuel, Cordier, Charlotte, Demerle, Clemence, Salem, Nassim, Wlosik, Julia, Orlanducci, Florence, Gorvel, Laurent, Fattori, Stephane, Hospital, Marie-Anne, Pakradouni, Jihane, Gregori, Emilie, Paul, Magali, Rochigneux, Philippe, Pagliardini, Thomas, Morey, Mathieu, Fauriat, Cyril, Dulphy, Nicolas, Toubert, Antoine, Luche, Herve, Malissen, Marie, Blaise, Didier, Nunès, Jacques A., Vey, Norbert, Olive, Daniel
Publicado 2021

Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

por Guilliams, Martin, Dutertre, Charles-Antoine, Scott, Charlotte L., McGovern, Naomi, Sichien, Dorine, Chakarov, Svetoslav, Van Gassen, Sofie, Chen, Jinmiao, Poidinger, Michael, De Prijck, Sofie, Tavernier, Simon J., Low, Ivy, Irac, Sergio Erdal, Mattar, Citra Nurfarah, Sumatoh, Hermi Rizal, Low, Gillian Hui Ling, Chung, Tam John Kit, Chan, Dedrick Kok Hong, Tan, Ker Kan, Hon, Tony Lim Kiat, Fossum, Even, Bogen, Bjarne, Choolani, Mahesh, Chan, Jerry Kok Yen, Larbi, Anis, Luche, Hervé, Henri, Sandrine, Saeys, Yvan, Newell, Evan William, Lambrecht, Bart N., Malissen, Bernard, Ginhoux, Florent
Publicado 2016