Selective small-molecule EPAC activators

por Luchowska-Stańska, Urszula, Morgan, David, Yarwood, Stephen J., Barker, Graeme
Publicado 2019

The novel exchange protein activated by cyclic AMP 1 (EPAC1) agonist, I942, regulates inflammatory gene expression in human umbilical vascular endothelial cells (HUVECs)

por Wiejak, Jolanta, van Basten, Boy, Luchowska-Stańska, Urszula, Hamilton, Graham, Yarwood, Stephen J.
Publicado 2019

Protein interaction, cytotoxic, transcriptomic and proteomic responses to structurally distinct EPAC1 activators in HUVECs

por Wiejak, Jolanta, Luchowska-Stańska, Urszula, Wang, Pingyuan, Zhou, Jia, Maffia, Pasquale, Morgan, David, Barker, Graeme, Yarwood, Stephen J.
Publicado 2022

Identification and Characterization of an Affimer Affinity Reagent for the Detection of the cAMP Sensor, EPAC1

por Buist, Hanna K., Luchowska-Stańska, Urszula, van Basten, Boy, Valli, Jessica, Smith, Brian O., Baillie, George S., Rickman, Colin, Ricketts, Bryon, Davidson, Alex, Hannam, Ryan, Sunderland, Joanne, Yarwood, Stephen J.
Publicado 2021

Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1

por M. Beck, Elizabeth, Parnell, Euan, Cowley, Angela, Porter, Alison, Gillespie, Jonathan, Robinson, John, Robinson, Lindsay, Pannifer, Andrew D., Hamon, Veronique, Jones, Philip, Morrison, Angus, McElroy, Stuart, Timmerman, Martin, Rutjes, Helma, Mahajan, Pravin, Wiejak, Jolanta, Luchowska-Stańska, Urszula, Morgan, David, Barker, Graeme, Rehmann, Holger, Yarwood, Stephen J.
Publicado 2019