Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells

por Lensch, Sarah, Herschl, Michael H, Ludwig, Connor H, Sinha, Joydeb, Hinks, Michaela M, Mukund, Adi, Fujimori, Taihei, Bintu, Lacramioara
Publicado 2022

The H3.3 K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation

por Sinha, Joydeb, Nickels, Jan F., Thurm, Abby R., Ludwig, Connor H., Archibald, Bella N., Hinks, Michaela M., Wan, Jun, Fang, Dong, Bintu, Lacramioara
Publicado 2023

Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

por Wang, Chao, Ward, Michael E., Chen, Robert, Liu, Kai, Tracy, Tara E., Chen, Xu, Xie, Min, Sohn, Peter Dongmin, Ludwig, Connor, Meyer-Franke, Anke, Karch, Celeste M., Ding, Sheng, Gan, Li
Publicado 2017

Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes

por Krencik, Robert, Seo, Kyounghee, van Asperen, Jessy V., Basu, Nupur, Cvetkovic, Caroline, Barlas, Saba, Chen, Robert, Ludwig, Connor, Wang, Chao, Ward, Michael E., Gan, Li, Horner, Philip J., Rowitch, David H., Ullian, Erik M.
Publicado 2017

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy

por Sayed, Faten A., Telpoukhovskaia, Maria, Kodama, Lay, Li, Yaqiao, Zhou, Yungui, Le, David, Hauduc, Axel, Ludwig, Connor, Gao, Fuying, Clelland, Claire, Zhan, Lihong, Cooper, Yonatan A., Davalos, Dimitrios, Akassoglou, Katerina, Coppola, Giovanni, Gan, Li
Publicado 2018