Dosimetric impact of Ac-227 in accelerator-produced Ac-225 for alpha-emitter radiopharmaceutical therapy of patients with hematological malignancies: a pharmacokinetic modeling ana...

por Sgouros, George, He, Bin, Ray, Nitya, Ludwig, Dale L., Frey, Eric C.
Publicado 2021

225Ac‐labeled CD33‐targeting antibody reverses resistance to Bcl‐2 inhibitor venetoclax in acute myeloid leukemia models

por Garg, Ravendra, Allen, Kevin J. H., Dawicki, Wojciech, Geoghegan, Eileen M., Ludwig, Dale L., Dadachova, Ekaterina
Publicado 2020

Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy

por Dawicki, Wojciech, Allen, Kevin J.H., Garg, Ravendra, Geoghegan, Eileen M., Berger, Mark S., Ludwig, Dale L., Dadachova, Ekaterina
Publicado 2020

Daratumumab-(225)Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors

por Dawicki, Wojciech, Allen, Kevin J.H., Jiao, Rubin, Malo, Mackenzie E., Helal, Muath, Berger, Mark S., Ludwig, Dale L., Dadachova, Ekaterina
Publicado 2019

Development of a novel and efficient cell culture flocculation process using a stimulus responsive polymer to streamline antibody purification processes

por Kang, Yun (Kenneth), Hamzik, James, Felo, Michael, Qi, Bo, Lee, Julia, Ng, Stanley, Liebisch, Gregory, Shanehsaz, Behnam, Singh, Nripen, Persaud, Kris, Ludwig, Dale L, Balderes, Paul
Publicado 2013

Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody

por Yin, Yongjun, Ren, Xiaodi, Smith, Craig, Guo, Qianxu, Malabunga, Maria, Guernah, Ilhem, Zhang, Yiwei, Shen, Juqun, Sun, Haijun, Chehab, Nabil, Loizos, Nick, Ludwig, Dale L., Ornitz, David M.
Publicado 2016

Removal of a C-terminal serine residue proximal to the inter-chain disulfide bond of a human IgG1 lambda light chain mediates enhanced antibody stability and antibody dependent cel...

por Shen, Yang, Zeng, Lin, Zhu, Aiping, Blanc, Tim, Patel, Dipa, Pennello, Anthony, Bari, Amtul, Ng, Stanley, Persaud, Kris, Kang, Yun (Kenneth), Balderes, Paul, Surguladze, David, Hindi, Sagit, Zhou, Qinwei, Ludwig, Dale L., Snavely, Marshall
Publicado 2013

Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054

por Li, Yiwen, Carpenito, Carmine, Wang, George, Surguladze, David, Forest, Amelie, Malabunga, Maria, Murphy, Mary, Zhang, Yiwei, Sonyi, Andreas, Chin, Darin, Burtrum, Douglas, Inigo, Ivan, Pennello, Anthony, Shen, Leyi, Malherbe, Laurent, Chen, Xinlei, Hall, Gerald, Haidar, Jaafar N., Ludwig, Dale L., Novosiadly, Ruslan D., Kalos, Michael
Publicado 2018

Correction to: Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054

por Li, Yiwen, Carpenito, Carmine, Wang, George, Surguladze, David, Forest, Amelie, Malabunga, Maria, Murphy, Mary, Zhang, Yiwei, Sonyi, Andreas, Chin, Darin, Burtrum, Douglas, Inigo, Ivan, Pennello, Anthony, Shen, Leyi, Malherbe, Laurent, Chen, Xinlei, Hall, Gerald, Haidar, Jaafar N., Ludwig, Dale L., Novosiadly, Ruslan D., Kalos, Michael
Publicado 2018

A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation

por Shen, Yang, Zeng, Lin, Novosyadlyy, Ruslan, Forest, Amelie, Zhu, Aiping, Korytko, Andrew, Zhang, Haifan, Eastman, Scott W, Topper, Michael, Hindi, Sagit, Covino, Nicole, Persaud, Kris, Kang, Yun, Burtrum, Douglas, Surguladze, David, Prewett, Marie, Chintharlapalli, Sudhakar, Wroblewski, Victor J, Shen, Juqun, Balderes, Paul, Zhu, Zhenping, Snavely, Marshall, Ludwig, Dale L
Publicado 2015