Editorial: RNA at a breaking point? Cytoplasmic cleavage and other post-transcriptional RNA processing in neurodevelopment and disease

por Piwecka, Monika, Luisier, Raphaelle, Andreassi, Catia
Publicado 2023

The predicted RNA-binding protein regulome of axonal mRNAs

por Luisier, Raphaëlle, Andreassi, Catia, Fournier, Lisa, Riccio, Antonella
Publicado 2023

Image‐based deep learning reveals the responses of human motor neurons to stress and VCP‐related ALS

por Verzat, Colombine, Harley, Jasmine, Patani, Rickie, Luisier, Raphaëlle
Publicado 2021

Mammary epithelial morphogenesis in 3D combinatorial microenvironments

por Luisier, Raphaelle, Girgin, Mehmet, Lutolf, Matthias P., Ranga, Adrian
Publicado 2020

Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS

por Tyzack, Giulia E, Manferrari, Giulia, Newcombe, Jia, Luscombe, Nicholas M, Luisier, Raphaelle, Patani, Rickie
Publicado 2020

Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

por Luisier, Raphaëlle, Unterberger, Elif B., Goodman, Jay I., Schwarz, Michael, Moggs, Jonathan, Terranova, Rémi, van Nimwegen, Erik
Publicado 2014

Automated and unbiased discrimination of ALS from control tissue at single cell resolution

por Hagemann, Cathleen, Tyzack, Giulia E., Taha, Doaa M., Devine, Helen, Greensmith, Linda, Newcombe, Jia, Patani, Rickie, Serio, Andrea, Luisier, Raphaëlle
Publicado 2021

Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis

por Petrić Howe, Marija, Crerar, Hamish, Neeves, Jacob, Harley, Jasmine, Tyzack, Giulia E., Klein, Pierre, Ramos, Andres, Patani, Rickie, Luisier, Raphaëlle
Publicado 2022

Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis

por Tyzack, Giulia E, Neeves, Jacob, Crerar, Hamish, Klein, Pierre, Ziff, Oliver, Taha, Doaa M, Luisier, Raphaëlle, Luscombe, Nicholas M, Patani, Rickie
Publicado 2021

Cytoplasmic cleavage of IMPA1 3′ UTR is necessary for maintaining axon integrity

por Andreassi, Catia, Luisier, Raphaëlle, Crerar, Hamish, Darsinou, Marousa, Blokzijl-Franke, Sasja, Lenn, Tchern, Luscombe, Nicholas M., Cuda, Giovanni, Gaspari, Marco, Saiardi, Adolfo, Riccio, Antonella
Publicado 2021

Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis

por Tyzack, Giulia E, Luisier, Raphaelle, Taha, Doaa M, Neeves, Jacob, Modic, Miha, Mitchell, Jamie S, Meyer, Ione, Greensmith, Linda, Newcombe, Jia, Ule, Jernej, Luscombe, Nicholas M, Patani, Rickie
Publicado 2019

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS

por Luisier, Raphaelle, Tyzack, Giulia E., Hall, Claire E., Mitchell, Jamie S., Devine, Helen, Taha, Doaa M., Malik, Bilal, Meyer, Ione, Greensmith, Linda, Newcombe, Jia, Ule, Jernej, Luscombe, Nicholas M., Patani, Rickie
Publicado 2018

Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology

por Ziff, Oliver J., Neeves, Jacob, Mitchell, Jamie, Tyzack, Giulia, Martinez-Ruiz, Carlos, Luisier, Raphaelle, Chakrabarti, Anob M., McGranahan, Nicholas, Litchfield, Kevin, Boulton, Simon J., Al-Chalabi, Ammar, Kelly, Gavin, Humphrey, Jack, Patani, Rickie
Publicado 2023

c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4(+) T cells

por Gabryšová, Leona, Alvarez-Martinez, Marisol, Luisier, Raphaëlle, Cox, Luke S., Sodenkamp, Jan, Hosking, Caroline, Pérez-Mazliah, Damián, Whicher, Charlotte, Kannan, Yashaswini, Potempa, Krzysztof, Wu, Xuemei, Bhaw, Leena, Wende, Hagen, Sieweke, Michael H., Elgar, Greg, Wilson, Mark, Briscoe, James, Metzis, Vicki, Langhorne, Jean, Luscombe, Nicholas M., O’Garra, Anne
Publicado 2018

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS

por Hall, Claire E., Yao, Zhi, Choi, Minee, Tyzack, Giulia E., Serio, Andrea, Luisier, Raphaelle, Harley, Jasmine, Preza, Elisavet, Arber, Charlie, Crisp, Sarah J., Watson, P. Marc D., Kullmann, Dimitri M., Abramov, Andrey Y., Wray, Selina, Burley, Russell, Loh, Samantha H.Y., Martins, L. Miguel, Stevens, Molly M., Luscombe, Nicholas M., Sibley, Christopher R., Lakatos, Andras, Ule, Jernej, Gandhi, Sonia, Patani, Rickie
Publicado 2017