Development of Acanthocheilonema viteae in Meriones shawi: Absence of microfilariae and production of active ES‐62

por Lumb, Felicity E., Doonan, James, Corbet, Marlene, Pineda, Miguel A., M. Harnett, Margaret, Harnett, William
Publicado 2020

Site-specific glycoproteomic characterization of ES-62: The major secreted product of the parasitic worm Acanthocheilonema viteae

por North, Simon J, Botchway, Kwamina, Doonan, James, Lumb, Felicity E, Dell, Anne, Harnett, William, Haslam, Stuart M
Publicado 2019

Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

por Lumb, Felicity E., Doonan, James, Bell, Kara S., Pineda, Miguel A., Corbet, Marlene, Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado 2017

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis

por Doonan, James, Lumb, Felicity E., Pineda, Miguel A., Tarafdar, Anuradha, Crowe, Jenny, Khan, Aneesah M., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado 2018

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

por Doonan, James, Tarafdar, Anuradha, Pineda, Miguel A., Lumb, Felicity E., Crowe, Jenny, Khan, Aneesah M., Hoskisson, Paul A., Harnett, Margaret M., Harnett, William
Publicado 2019

Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts

por Corbet, Marlene, Pineda, Miguel A., Yang, Kun, Tarafdar, Anuradha, McGrath, Sarah, Nakagawa, Rinako, Lumb, Felicity E., Suckling, Colin J., Harnett, William, Harnett, Margaret M.
Publicado 2021

The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62

por Bell, Kara S., Al-Riyami, Lamyaa, Lumb, Felicity E., Britton, Graham J., Poole, Alastair W., Williams, Christopher M., Braun, Ursula, Leitges, Michael, Harnett, Margaret M., Harnett, William
Publicado 2015

The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing

por Harnett, Margaret M., Doonan, James, Lumb, Felicity E., Crowe, Jenny, Damink, Roel Olde, Buitrago, Geraldine, Duncombe-Moore, Josephine, Wilkinson, Debbie I., Suckling, Colin J., Selman, Colin, Harnett, William
Publicado 2022

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

por Crowe, Jenny, Lumb, Felicity E., Doonan, James, Broussard, Margaux, Tarafdar, Anuradha, Pineda, Miguel A., Landabaso, Carmen, Mulvey, Lorna, Hoskisson, Paul A., Babayan, Simon A., Selman, Colin, Harnett, William, Harnett, Margaret M.
Publicado 2020

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter...

por Rzepecka, Justyna, Pineda, Miguel A., Al-Riyami, Lamyaa, Rodgers, David T., Huggan, Judith K., Lumb, Felicity E., Khalaf, Abedawn I., Meakin, Paul J., Corbet, Marlene, Ashford, Michael L., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Publicado 2015

Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease

por Doonan, James, Thomas, David, Wong, Michelle H., Ramage, Hazel J., Al-Riyami, Lamyaa, Lumb, Felicity E., Bell, Kara S., Fairlie-Clarke, Karen J., Suckling, Colin J., Michelsen, Kathrin S., Jiang, Hui-Rong, Cooke, Anne, Harnett, Margaret M., Harnett, William
Publicado 2018