Thresholding Gini variable importance with a single-trained random forest: An empirical Bayes approach

por Dunne, Robert, Reguant, Roc, Ramarao-Milne, Priya, Szul, Piotr, Sng, Letitia M.F., Lundberg, Mischa, Twine, Natalie A., Bauer, Denis C.
Publicado 2023

Novel Alzheimer’s disease genes and epistasis identified using machine learning GWAS platform

por Lundberg, Mischa, Sng, Letitia M. F., Szul, Piotr, Dunne, Rob, Bayat, Arash, Burnham, Samantha C., Bauer, Denis C., Twine, Natalie A.
Publicado 2023

Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development

por Gerdes, Patricia, Chan, Dorothy, Lundberg, Mischa, Sanchez-Luque, Francisco J., Bodea, Gabriela O., Ewing, Adam D., Faulkner, Geoffrey J., Richardson, Sandra R.
Publicado 2023

Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs

por Hwang, Liang-Dar, Tubbs, Justin D., Luong, Justin, Lundberg, Mischa, Moen, Gunn-Helen, Wang, Geng, Warrington, Nicole M., Sham, Pak C., Cuellar-Partida, Gabriel, Evans, David M.
Publicado 2020

Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth

por Brito Nunes, Caroline, Huang, Peiyuan, Wang, Geng, Lundberg, Mischa, D’Urso, Shannon, Wootton, Robyn E, Borges, Maria Carolina, Lawlor, Deborah A, Warrington, Nicole M, Evans, David M, Hwang, Liang-Dar, Moen, Gunn-Helen
Publicado 2022

A metabolic associated fatty liver disease risk variant in MBOAT7 regulates toll like receptor induced outcomes

por Alharthi, Jawaher, Bayoumi, Ali, Thabet, Khaled, Pan, Ziyan, Gloss, Brian S., Latchoumanin, Olivier, Lundberg, Mischa, Twine, Natalie A., McLeod, Duncan, Alenizi, Shafi, Adams, Leon A., Weltman, Martin, Berg, Thomas, Liddle, Christopher, George, Jacob, Eslam, Mohammed
Publicado 2022

Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease

por Bergen, Dylan J. M., Tong, Qiao, Shukla, Ankit, Newham, Elis, Zethof, Jan, Lundberg, Mischa, Ryan, Rebecca, Youlten, Scott E., Frysz, Monika, Croucher, Peter I., Flik, Gert, Richardson, Rebecca J., Kemp, John P., Hammond, Chrissy L., Metz, Juriaan R.
Publicado 2022

A hidden layer of structural variation in transposable elements reveals potential genetic modifiers in human disease-risk loci

por van Bree, Elisabeth J., Guimarães, Rita L.F.P., Lundberg, Mischa, Blujdea, Elena R., Rosenkrantz, Jimi L., White, Fred T.G., Poppinga, Josse, Ferrer-Raventós, Paula, Schneider, Anne-Fleur E., Clayton, Isabella, Haussler, David, Reinders, Marcel J.T., Holstege, Henne, Ewing, Adam D., Moses, Colette, Jacobs, Frank M.J.
Publicado 2022

The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space w...

por Faber, Benjamin G., Frysz, Monika, Boer, Cindy G., Evans, Daniel S., Ebsim, Raja, Flynn, Kaitlyn A., Lundberg, Mischa, Southam, Lorraine, Hartley, April, Saunders, Fiona R., Lindner, Claudia, Gregory, Jennifer S., Aspden, Richard M., Lane, Nancy E., Harvey, Nicholas C., Evans, David M., Zeggini, Eleftheria, Davey Smith, George, Cootes, Timothy, Van Meurs, Joyce, Kemp, John P., Tobias, Jonathan H.
Publicado 2023

Identification of susceptibility variants to benign childhood epilepsy with centro-temporal spikes (BECTS) in Chinese Han population

por Shi, Xiu-Yu, Wang, Geng, Li, Ting, Li, Zhixiu, Leo, Paul, Liu, Zhisheng, Wu, Gefei, Zhu, Hongmin, Zhang, Yuqin, Li, Dong, Gao, Li, Yang, Liu, Wang, Wei, Liao, Jianxiang, Wang, Jiwen, Zhou, Shuizhen, Wang, Hua, Li, Xiaojing, Gao, Jingyun, Zhang, Li, Shu, Xiaomei, Li, Dan, Li, Yan, Chen, Chunhong, Zhang, Xiuju, Partida, Gabriel Cuellar, Lundberg, Mischa, Reutens, David, Bartlett, Perry, Brown, Matthew A, Zou, Li-Ping, Xu, Huji
Publicado 2020

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

por McDonald, Michelle M., Khoo, Weng Hua, Ng, Pei Ying, Xiao, Ya, Zamerli, Jad, Thatcher, Peter, Kyaw, Wunna, Pathmanandavel, Karrnan, Grootveld, Abigail K., Moran, Imogen, Butt, Danyal, Nguyen, Akira, Warren, Sean, Biro, Maté, Butterfield, Natalie C., Guilfoyle, Siobhan E., Komla-Ebri, Davide, Dack, Michael R.G., Dewhurst, Hannah F., Logan, John G., Li, Yongxiao, Mohanty, Sindhu T., Byrne, Niall, Terry, Rachael L., Simic, Marija K., Chai, Ryan, Quinn, Julian M.W., Youlten, Scott E., Pettitt, Jessica A., Abi-Hanna, David, Jain, Rohit, Weninger, Wolfgang, Lundberg, Mischa, Sun, Shuting, Ebetino, Frank H., Timpson, Paul, Lee, Woei Ming, Baldock, Paul A., Rogers, Michael J., Brink, Robert, Williams, Graham R., Bassett, J.H. Duncan, Kemp, John P., Pavlos, Nathan J., Croucher, Peter I., Phan, Tri Giang
Publicado 2021

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

por McDonald, Michelle M., Khoo, Weng Hua, Ng, Pei Ying, Xiao, Ya, Zamerli, Jad, Thatcher, Peter, Kyaw, Wunna, Pathmanandavel, Karrnan, Grootveld, Abigail K., Moran, Imogen, Butt, Danyal, Nguyen, Akira, Corr, Alexander, Warren, Sean, Biro, Maté, Butterfield, Natalie C., Guilfoyle, Siobhan E., Komla-Ebri, Davide, Dack, Michael R.G., Dewhurst, Hannah F., Logan, John G., Li, Yongxiao, Mohanty, Sindhu T., Byrne, Niall, Terry, Rachael L., Simic, Marija K., Chai, Ryan, Quinn, Julian M.W., Youlten, Scott E., Pettitt, Jessica A., Abi-Hanna, David, Jain, Rohit, Weninger, Wolfgang, Lundberg, Mischa, Sun, Shuting, Ebetino, Frank H., Timpson, Paul, Lee, Woei Ming, Baldock, Paul A., Rogers, Michael J., Brink, Robert, Williams, Graham R., Bassett, J.H. Duncan, Kemp, John P., Pavlos, Nathan J., Croucher, Peter I., Phan, Tri Giang
Publicado 2021