CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase

por Luo, Kuntian, Deng, Min, Li, Yunhui, Wu, Chenming, Xu, Ziwen, Yuan, Jian, Lou, Zhenkun
Publicado 2015

HERC2-USP20 axis regulates DNA damage checkpoint through Claspin

por Yuan, Jian, Luo, Kuntian, Deng, Min, Li, Yunhui, Yin, Ping, Gao, Bowen, Fang, Yuan, Wu, Puqiang, Liu, Tongzheng, Lou, Zhenkun
Publicado 2014

A phosphorylation–deubiquitination cascade regulates the BRCA2–RAD51 axis in homologous recombination

por Luo, Kuntian, Li, Lei, Li, Yunhui, Wu, Chenming, Yin, Yujiao, Chen, Yuping, Deng, Min, Nowsheen, Somaira, Yuan, Jian, Lou, Zhenkun
Publicado 2016

USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response

por Li, Yunhui, Luo, Kuntian, Yin, Yujiao, Wu, Chenming, Deng, Min, Li, Lei, Chen, Yuping, Nowsheen, Somaira, Lou, Zhenkun, Yuan, Jian
Publicado 2017

SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response

por Guo, Guijie, Gao, Ming, Gao, Xiaochen, Zhu, Bibo, Huang, Jinzhou, Luo, Kuntian, Zhang, Yong, Sun, Jie, Deng, Min, Lou, Zhenkun
Publicado 2021

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

por Pei, Huadong, Zhang, Lindsey, Luo, Kuntian, Qin, Yuxin, Chesi, Marta, Fei, Frances, Bergsagel, P. Leif, Wang, Liewei, You, Zhongsheng, Lou, Zhenkun
Publicado 2011

The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization

por Li, Lei, Liu, Tongzheng, Li, Yunhui, Wu, Chenming, Luo, Kuntian, Yin, Yujiao, Chen, Yuping, Nowsheen, Somaira, Wu, Jinhuan, Lou, Zhenkun, Yuan, Jian
Publicado 2018

Resveratrol induces apoptosis by directly targeting Ras-GTPase activating protein SH3 domain binding protein 1 (G3BP1)

por Oi, Naomi, Yuan, Jian, Malakhova, Margarita, Luo, Kuntian, Li, Yunhui, Ryu, Joohyun, Zhang, Lei, Bode, Ann M., Xu, Zengguang, Li, Yan, Lou, Zhenkun, Dong, Zigang
Publicado 2014

A novel UCHL(3) inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair

por Song, Zhiwang, Tu, Xinyi, Zhou, Qin, Huang, Jinzhou, Chen, Yuping, Liu, Jiaqi, Lee, SeungBaek, Kim, Wootae, Nowsheen, Somaira, Luo, Kuntian, Yuan, Jian, Lou, Zhenkun
Publicado 2019

The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization

por Yan, Yuanliang, Xu, Zhijie, Huang, Jinzhou, Guo, Guijie, Gao, Ming, Kim, Wootae, Zeng, Xiangyu, Kloeber, Jake A, Zhu, Qian, Zhao, Fei, Luo, Kuntian, Lou, Zhenkun
Publicado 2020

ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex

por Kim, Wootae, Zhao, Fei, Wu, Rentian, Qin, Sisi, Nowsheen, Somaira, Huang, Jinzhou, Zhou, Qin, Chen, Yuping, Deng, Min, Guo, Guijie, Luo, Kuntian, Lou, Zhenkun, Yuan, Jian
Publicado 2019

ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage

por Nowsheen, Somaira, Aziz, Khaled, Luo, Kuntian, Deng, Min, Qin, Bo, Yuan, Jian, Jeganathan, Karthik B., Yu, Jia, Zhang, Henan, Ding, Wei, van Deursen, Jan M., Lou, Zhenkun
Publicado 2018

USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP

por Gao, Ming, Guo, Guijie, Huang, Jinzhou, Kloeber, Jake A., Zhao, Fei, Deng, Min, Tu, Xinyi, Kim, Wootae, Zhou, Qin, Zhang, Chao, Yin, Ping, Luo, Kuntian, Lou, Zhenkun
Publicado 2020

LRRK2 inhibition potentiates PARP inhibitor cytotoxicity through inhibiting homologous recombination‐mediated DNA double strand break repair

por Chen, Lifeng, Hou, Jing, Zeng, Xiangyu, Guo, Qiang, Deng, Min, Kloeber, Jake A, Tu, Xinyi, Zhao, Fei, Wu, Zheming, Huang, Jinzhou, Luo, Kuntian, Kim, Wootae, Lou, Zhenkun
Publicado 2021

L3MBTL2 orchestrates ubiquitin signaling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage

por Nowsheen, Somaira, Aziz, Khaled, Aziz, Asef, Deng, Min, Qin, Bo, Luo, Kuntian, Jeganathan, Karthikbabu B, Zhang, Henan, Liu, Tongzheng, Yu, Jia, Deng, Yibin, Yuan, Jian, Ding, Wei, van Deursen, Jan M, Lou, Zhenkun
Publicado 2018

The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair

por Zhou, Qin, Huang, Jinzhou, Zhang, Chao, Zhao, Fei, Kim, Wootae, Tu, Xinyi, Zhang, Yong, Nowsheen, Somaira, Zhu, Qian, Deng, Min, Chen, Yuping, Qin, Bo, Luo, Kuntian, Liu, Baohua, Lou, Zhenkun, Mutter, Robert W., Yuan, Jian
Publicado 2020

Author Correction: The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair

por Zhou, Qin, Huang, Jinzhou, Zhang, Chao, Zhao, Fei, Kim, Wootae, Tu, Xinyi, Zhang, Yong, Nowsheen, Somaira, Zhu, Qian, Deng, Min, Chen, Yuping, Qin, Bo, Luo, Kuntian, Liu, Baohua, Lou, Zhenkun, Mutter, Robert W., Yuan, Jian
Publicado 2022

RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination

por Zhu, Qian, Huang, Jinzhou, Huang, Hongyang, Li, Huan, Yi, Peiqiang, Kloeber, Jake A., Yuan, Jian, Chen, Yuping, Deng, Min, Luo, Kuntian, Gao, Ming, Guo, Guijie, Tu, Xinyi, Yin, Ping, Zhang, Yong, Su, Jun, Chen, Jiayi, Lou, Zhenkun
Publicado 2021

USP37 regulates DNA damage response through stabilizing and deubiquitinating BLM

por Wu, Chenming, Chang, Yiming, Chen, Junliang, Su, Yang, Li, Lei, Chen, Yuping, Li, Yunhui, Wu, Jinhuan, Huang, Jinzhou, Zhao, Fei, Wang, Wenrui, Yin, Hui, Wang, Shunli, Jin, Mingpeng, Lou, Zhenkun, Zhu, Wei-Guo, Luo, Kuntian, Zhang, Jie, Yuan, Jian
Publicado 2021

Syk-dependent alternative homologous recombination activation promotes cancer resistance to DNA targeted therapy

por Zhou, Qin, Tu, Xinyi, Hou, Xiaonan, Yu, Jia, Zhao, Fei, Huang, Jinzhou, Kloeber, Jake, Olson, Anna, Gao, Ming, Luo, Kuntian, Zhu, Shouhai, Wu, Zheming, Zhang, Yong, Sun, Chenyu, Zeng, Xiangyu, Schoolmeester, Kenneth, Weroha, John, Wang, Liewei, Mutter, Robert, Lou, Zhenkun
Publicado 2023