Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis

por Gao, Peng, Shen, Shuo, Li, Xiaodong, Liu, Dandan, Meng, Yuqing, Liu, Yanqing, Zhu, Yongping, Zhang, Junzhe, Luo, Piao, Gu, Liwei
Publicado 2020

Neuroprotective Effects of Celastrol in Neurodegenerative Diseases-Unscramble Its Major Mechanisms of Action and Targets

por Liu, Dandan, Zhang, Qian, Luo, Piao, Gu, Liwei, Shen, Shengnan, Tang, Huan, Zhang, Ying, Lyu, Ming, Shi, Qiaoli, Yang, Chuanbin, Wang, Jigang
Publicado 2022

Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy

por Chen, Jiayun, Luo, Piao, Wang, Chen, Yang, Chuanbin, Bai, Yunmeng, He, Xueling, Zhang, Qian, Zhang, Junzhe, Yang, Jing, Wang, Shuang, Wang, Jigang
Publicado 2022

Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia–reperfusion

por Liu, Dan-Dan, Luo, Piao, Gu, Liwei, Zhang, Qian, Gao, Peng, Zhu, Yongping, Chen, Xiao, Guo, Qiuyan, Zhang, Junzhe, Ma, Nan, Wang, Jigang
Publicado 2021

Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics

por Zhang, Qian, Luo, Piao, Chen, Jiayun, Yang, Chuanbin, Xia, Fei, Zhang, Junzhe, Tang, Huan, Liu, Dandan, Gu, Liwei, Shi, Qiaoli, He, Xueling, Yang, Tong, Wang, Jigang
Publicado 2022

Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics

por Luo, Piao, Chen, Jiayun, Zhang, Qian, Xia, Fei, Wang, Chen, Bai, Yunmeng, Tang, Huan, Liu, Dandan, Gu, Liwei, Du, Qingfeng, Xiao, Wei, Yang, Chuanbin, Wang, Jigang
Publicado 2022

Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1

por Luo, Piao, Liu, Dandan, Zhang, Qian, Yang, Fan, Wong, Yin-Kwan, Xia, Fei, Zhang, Junzhe, Chen, Jiayun, Tian, Ya, Yang, Chuanbin, Dai, Lingyun, Shen, Han-Ming, Wang, Jigang
Publicado 2022

Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis

por Chen, Jiayun, He, Xueling, Bai, Yunmeng, Liu, Jing, Wong, Yin Kwan, Xie, Lulin, Zhang, Qian, Luo, Piao, Gao, Peng, Gu, Liwei, Guo, Qiuyan, Cheng, Guangqing, Wang, Chen, Wang, Jigang
Publicado 2023

Hysteresis effects of different levels of storm flooding on susceptible enteric infectious diseases in a central city of China

por Luo, Piao-yi, Chen, Meng-xiang, Kuang, Wen-tao, Ni, Han, Zhao, Jin, Dai, Hao-yun, Ren, Xiang, Yi, Shang-hui, Hong, Xiu-qin, Zha, Wen-ting, Lv, Yuan
Publicado 2023

Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and...

por Shi, Qiaoli, Wang, Qixin, Chen, Jiayun, Xia, Fei, Qiu, Chong, Li, Min, Zhao, Minghong, Zhang, Qian, Luo, Piao, Lu, Tianming, Zhang, Ying, Xu, Liting, He, Xueling, Zhong, Tianyu, Lin, Na, Guo, Qiuyan
Publicado 2022

18beta-glycyrrhetinic acid induces ROS-mediated apoptosis to ameliorate hepatic fibrosis by targeting PRDX1/2 in activated HSCs

por Zhang, Qian, Luo, Piao, Zheng, Liuhai, Chen, Jiayun, Zhang, Junzhe, Tang, Huan, Liu, Dandan, He, Xueling, Shi, Qiaoli, Gu, Liwei, Li, Jiahao, Guo, Qiuyan, Yang, Chuanbin, Wong, Yin Kwan, Xia, Fei, Wang, Jigang
Publicado 2022

Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect

por Luo, Piao, Zhang, Qian, Zhong, Tian-Yu, Chen, Jia-Yun, Zhang, Jun-Zhe, Tian, Ya, Zheng, Liu-Hai, Yang, Fan, Dai, Ling-Yun, Zou, Chang, Li, Zhi-Jie, Liu, Jing-Hua, Wang, Ji-Gang
Publicado 2022

Single‐cell RNA sequencing reveals the effects of capsaicin in the treatment of sepsis‐induced liver injury

por Zhang, Qian, Liu, Jing, Shen, Jing, Ou, Jinhuan, Wong, Yin Kwan, Xie, Lulin, Huang, Jingnan, Zhang, Chunting, Fu, Chunjin, Chen, Junhui, Chen, Jiayun, He, Xueling, Shi, Fei, Luo, Piao, Gong, Ping, Liu, Xueyan, Wang, Jigang
Publicado 2023

Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress

por Wang, Qixin, Huang, Yuwen, Li, Yu, Zhang, Luyun, Tang, Huan, Zhang, Junzhe, Cheng, Guangqing, Zhao, Minghong, Lu, Tianming, Zhang, Qian, Luo, Piao, Zhu, Yinhua, Xia, Fei, Zhang, Ying, Liu, Dandan, Wang, Chen, Li, Haiyan, Qiu, Chong, Wang, Jigang, Guo, Qiuyan
Publicado 2022

Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice

por Bai, Yun-Meng, Yang, Fan, Luo, Piao, Xie, Lu-Lin, Chen, Jun-Hui, Guan, Yu-Dong, Zhou, Hong-Chao, Xu, Teng-Fei, Hao, Hui-Wen, Chen, Bing, Zhao, Jia-Hui, Liang, Cai-Ling, Dai, Ling-Yun, Geng, Qing-Shan, Wang, Ji-Gang
Publicado 2023