The genomic landscape of sensitivity to arsenic trioxide uncovered by genome-wide CRISPR-Cas9 screening

por Chen, Jun-Zhu, Wang, Li-Na, Luo, Xue-Qun, Tang, Yan-Lai
Publicado 2023

The application of genome-wide CRISPR-Cas9 screens to dissect the molecular mechanisms of toxins

por Wang, Bei, Chen, Jun-Zhu, Luo, Xue-Qun, Wan, Guo-Hui, Tang, Yan-Lai, Wang, Qiao-Ping
Publicado 2022

High-Level Expression, Purification and Large-Scale Production of l-Methionine γ-Lyase from Idiomarina as a Novel Anti-Leukemic Drug

por Huang, Kui-Ying, Hu, Hai-Yan, Tang, Yan-Lai, Xia, Feng-Geng, Luo, Xue-Qun, Liu, Jian-Zhong
Publicado 2015

A CRISPR/CAS9‐based strategy targets the personalized chimeric neosequence in fusion‐driven cancer genome for precision medicine

por Huang, Wei, Zeng, Zhan‐Cheng, Wang, Wen‐Tao, Sun, Yu‐Meng, Chen, Yue‐Qin, Luo, Xue‐Qun, Fang, Ke
Publicado 2021

Upregulation of the proto-oncogene Bmi-1 predicts a poor prognosis in pediatric acute lymphoblastic leukemia

por Peng, Hong-Xia, Liu, Xiao-Dan, Luo, Zi-Yan, Zhang, Xiao-Hong, Luo, Xue-Qun, Chen, Xiao, Jiang, Hua, Xu, Ling
Publicado 2017

Clinical characteristics of sitosterolemic children with xanthomas as the first manifestation

por Zhang, Jun, Chen, Qiu-li, Guo, Song, Li, Yan-hong, Li, Chuan, Zheng, Ru-jiang, Luo, Xue-qun, Ma, Hua-mei
Publicado 2022

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

por Chen, Zhen-Hua, Wang, Wen-Tao, Huang, Wei, Fang, Ke, Sun, Yu-Meng, Liu, Shu-Rong, Luo, Xue-Qun, Chen, Yue-Qin
Publicado 2017

Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia

por Zhang, Hua, Luo, Xue-Qun, Feng, Dan-Dan, Zhang, Xing-Ju, Wu, Jun, Zheng, Yu-Sheng, Chen, Xiao, Xu, Ling, Chen, Yue-Qin
Publicado 2011

MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47

por Huang, Wei, Wang, Wen-Tao, Fang, Ke, Chen, Zhen-Hua, Sun, Yu-Meng, Han, Cai, Sun, Lin-Yu, Luo, Xue-Qun, Chen, Yue-Qin
Publicado 2018

MicroRNA Patterns Associated with Clinical Prognostic Parameters and CNS Relapse Prediction in Pediatric Acute Leukemia

por Zhang, Hua, Luo, Xue-Qun, Zhang, Peng, Huang, Li-Bin, Zheng, Yu-Sheng, Wu, Jun, Zhou, Hui, Qu, Liang-Hu, Xu, Ling, Chen, Yue-Qin
Publicado 2009

LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1

por Sun, Lin-Yu, Li, Xiao-Juan, Sun, Yu-Meng, Huang, Wei, Fang, Ke, Han, Cai, Chen, Zhen-Hua, Luo, Xue-Qun, Chen, Yue-Qin, Wang, Wen-Tao
Publicado 2018

Encephalopathy and brain atrophy during induction chemotherapy in acute lymphoblastic leukemia

por Li, Qiao‐Ru, Fu, Si‐Mao, Mo, Yin‐Lei, Li, Yu, Liang, Cong, Wang, Li‐Na, Tang, Wen‐Yan, Huang, Li‐Bin, Luo, Xue‐Qun, Tang, Yan‐Lai
Publicado 2020

Down-regulated miR-331–5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia

por Feng, Dan-Dan, Zhang, Hua, Zhang, Peng, Zheng, Yu-Sheng, Zhang, Xing-Ju, Han, Bo-Wei, Luo, Xue-Qun, Xu, Ling, Zhou, Hui, Qu, Liang-Hu, Chen, Yue-Qin
Publicado 2011

Genome-Wide Analysis of Small RNA and Novel MicroRNA Discovery in Human Acute Lymphoblastic Leukemia Based on Extensive Sequencing Approach

por Zhang, Hua, Yang, Jian-Hua, Zheng, Yu-Sheng, Zhang, Peng, Chen, Xiao, Wu, Jun, Xu, Ling, Luo, Xue-Qun, Ke, Zhi-Yong, Zhou, Hui, Qu, Liang-Hu, Chen, Yue-Qin
Publicado 2009

Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies

por Chen, Zhen-Hua, Chen, Tian-Qi, Zeng, Zhan-Cheng, Wang, Dan, Han, Cai, Sun, Yu-Meng, Huang, Wei, Sun, Lin-Yu, Fang, Ke, Chen, Yue-Qin, Luo, Xue-Qun, Wang, Wen-Tao
Publicado 2020

Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression

por Fang, Ke, Huang, Wei, Sun, Yu-Meng, Chen, Tian-Qi, Zeng, Zhan-Cheng, Yang, Qian-Qian, Pan, Qi, Han, Cai, Sun, Lin-Yu, Luo, Xue-Qun, Wang, Wen-Tao, Chen, Yue-Qin
Publicado 2020

The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1

por Huang, Wei, Sun, Yu-Meng, Pan, Qi, Fang, Ke, Chen, Xiao-Tong, Zeng, Zhan-Cheng, Chen, Tian-Qi, Zhu, Shun-Xin, Huang, Li-Bin, Luo, Xue-Qun, Wang, Wen-Tao, Chen, Yue-Qin
Publicado 2022

Case Report: CD19 and CD20 monoclonal antibodies with sequential chemotherapy for refractory acute B-lymphocytic leukemia in children

por Li, Jia-Nan, Li, Yu, Lin, Ji-Xun, Wang, Li-Na, Zhang, Xiao-Li, Ouyang, Juan, Chen, Du-Bo, Chen, Shao-Qian, Li, Jun-Xun, Luo, Xue-Qun, Tang, Yan-Lai, Huang, Li-Bin
Publicado 2023

Arsenic trioxide induces autophagic degradation of the FLT3-ITD mutated protein in FLT3-ITD acute myeloid leukemia cells

por Liu, Xiao-Jian, Wang, Li-Na, Zhang, Zu-Han, Liang, Cong, Li, Yu, Luo, Jie-Si, Peng, Chun-Jin, Zhang, Xiao-Li, Ke, Zhi-Yong, Huang, Li-Bin, Tang, Yan-Lai, Luo, Xue-Qun
Publicado 2020

The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia

por Wang, Wen-Tao, Chen, Tian-Qi, Zeng, Zhan-Cheng, Pan, Qi, Huang, Wei, Han, Cai, Fang, Ke, Sun, Lin-Yu, Yang, Qian-Qian, Wang, Dan, Luo, Xue-Qun, Sun, Yu-Meng, Chen, Yue-Qin
Publicado 2020