Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension

por Zhu, Na, Pauciulo, Michael W., Welch, Carrie L., Lutz, Katie A., Coleman, Anna W., Gonzaga-Jauregui, Claudia, Wang, Jiayao, Grimes, Joseph M., Martin, Lisa J., He, Hua, Shen, Yufeng, Chung, Wendy K., Nichols, William C.
Publicado 2019

Correction to: Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension

por Zhu, Na, Pauciulo, Michael W., Welch, Carrie L., Lutz, Katie A., Coleman, Anna W., Gonzaga-Jauregui, Claudia, Wang, Jiayao, Grimes, Joseph M., Martin, Lisa J., He, Hua, Shen, Yufeng, Chung, Wendy K., Nichols, William C.
Publicado 2022

RASA3 is a candidate gene in sickle cell disease‐associated pulmonary hypertension and pulmonary arterial hypertension

por Prohaska, Clare C., Zhang, Xu, Schwantes‐An, Tae‐Hwi L., Stearman, Robert S., Hooker, Stanley, Kittles, Rick A., Aldred, Micheala A., Lutz, Katie A., Pauciulo, Michael W., Nichols, William C., Desai, Ankit A., Gordeuk, Victor R., Machado, Roberto F.
Publicado 2023

Hepatoma‐derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival

por Yang, Jun, Ambade, Anjira S., Nies, Melanie, Griffiths, Megan, Damico, Rachel, Vaidya, Dhananjay, Brandal, Stephanie, Pauciulo, Michael W., Lutz, Katie A., Coleman, Anna W., Nichols, William C., Austin, Eric D., Ivy, Dunbar, Hassoun, Paul M., Everett, Allen D.
Publicado 2022

United States Pulmonary Hypertension Scientific Registry (USPHSR): rationale, design, and clinical implications

por Elliott, C. Gregory, Austin, Eric D., Badesch, David, Badlam, Jessica, Benza, Raymond L., Chung, Wendy K., Farber, Harrison W., Feldkircher, Kathy, Frost, Adaani E., Poms, Abby D., Lutz, Katie A., Pauciulo, Michael W., Yu, Chang, Nichols, William C.
Publicado 2019

The angiostatic peptide endostatin enhances mortality risk prediction in pulmonary arterial hypertension

por Simpson, Catherine E., Griffiths, Megan, Yang, Jun, Nies, Melanie K., Vaidya, R. Dhananjay, Brandal, Stephanie, Martin, Lisa J., Pauciulo, Michael W., Lutz, Katie A., Coleman, Anna W., Austin, Eric D., Ivy, D. Dunbar, Nichols, William C., Everett, Allen D., Hassoun, Paul M., Damico, Rachel L.
Publicado 2021

COL18A1 genotypic associations with endostatin levels and clinical features in pulmonary arterial hypertension: a quantitative trait association study

por Simpson, Catherine E., Griffiths, Megan, Yang, Jun, Nies, Melanie K., Vaidya, Dhananjay, Brandal, Stephanie, Martin, Lisa J., Pauciulo, Michael W., Lutz, Katie A., Coleman, Anna W., Austin, Eric D., Ivy, D. Dunbar, Nichols, William C., Everett, Allen D., Hassoun, Paul M., Damico, Rachel L.
Publicado 2022

Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease

por Zhu, Na, Welch, Carrie L., Wang, Jiayao, Allen, Philip M., Gonzaga-Jauregui, Claudia, Ma, Lijiang, King, Alejandra K., Krishnan, Usha, Rosenzweig, Erika B., Ivy, D. Dunbar, Austin, Eric D., Hamid, Rizwan, Pauciulo, Michael W., Lutz, Katie A., Nichols, William C., Reid, Jeffrey G., Overton, John D., Baras, Aris, Dewey, Frederick E., Shen, Yufeng, Chung, Wendy K.
Publicado 2018

Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH

por Zhu, Na, Swietlik, Emilia M., Welch, Carrie L., Pauciulo, Michael W., Hagen, Jacob J., Zhou, Xueya, Guo, Yicheng, Karten, Johannes, Pandya, Divya, Tilly, Tobias, Lutz, Katie A., Martin, Jennifer M., Treacy, Carmen M., Rosenzweig, Erika B., Krishnan, Usha, Coleman, Anna W., Gonzaga-Juaregui, Claudia, Lawrie, Allan, Trembath, Richard C., Wilkins, Martin R., Morrell, Nicholas W., Shen, Yufeng, Gräf, Stefan, Nichols, William C., Chung, Wendy K.
Publicado 2021

Correction to: Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH

por Zhu, Na, Swietlik, Emilia M., Welch, Carrie L., Pauciulo, Michael W., Hagen, Jacob J., Zhou, Xueya, Guo, Yicheng, Karten, Johannes, Pandya, Divya, Tilly, Tobias, Lutz, Katie A., Martin, Jennifer M., Treacy, Carmen M., Rosenzweig, Erika B., Krishnan, Usha, Coleman, Anna W., Gonzaga-Jauregui, Claudia, Lawrie, Allan, Trembath, Richard C., Wilkins, Martin R., Morrell, Nicholas W., Shen, Yufeng, Gräf, Stefan, Nichols, William C., Chung, Wendy K.
Publicado 2021

SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics

por Sangam, Shreya, Sun, Xutong, Schwantes-An, Tae-Hwi, Yegambaram, Manivannan, Lu, Qing, Shi, Yinan, Cook, Todd, Fisher, Amanda, Frump, Andrea L., Coleman, Anna, Sun, Yanan, Liang, Shuxin, Crawford, Howard, Lutz, Katie A., Maun, Avinash D., Pauciulo, Michael W., Karnes, Jason H., Chaudhary, Ketul R., Stewart, Duncan J., Langlais, Paul R., Jain, Mohit, Alotaibi, Mona, Lahm, Tim, Jin, Yan, Gu, Haiwei, Tang, Haiyang, Nichols, William C., Black, Stephen M., Desai, Ankit A.
Publicado 2023

Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension

por Toshner, Mark, Church, Colin, Harbaum, Lars, Rhodes, Christopher, Villar Moreschi, Sofia S., Liley, James, Jones, Rowena, Arora, Amit, Batai, Ken, Desai, Ankit A., Coghlan, John G., Gibbs, J. Simon R., Gor, Dee, Gräf, Stefan, Harlow, Louise, Hernandez-Sanchez, Jules, Howard, Luke S., Humbert, Marc, Karnes, Jason, Kiely, David G., Kittles, Rick, Knightbridge, Emily, Lam, Brian, Lutz, Katie A., Nichols, William C., Pauciulo, Michael W., Pepke-Zaba, Joanna, Suntharalingam, Jay, Soubrier, Florent, Trembath, Richard C., Schwantes-An, Tae-Hwi L., Wort, S. John, Wilkins, Martin R., Gaine, Sean, Morrell, Nicholas W., Corris, Paul A.
Publicado 2022

Bayesian Inference Associates Rare KDR Variants With Specific Phenotypes in Pulmonary Arterial Hypertension

por Swietlik, Emilia M., Greene, Daniel, Zhu, Na, Megy, Karyn, Cogliano, Marcella, Rajaram, Smitha, Pandya, Divya, Tilly, Tobias, Lutz, Katie A., Welch, Carrie C.L., Pauciulo, Michael W., Southgate, Laura, Martin, Jennifer M., Treacy, Carmen M., Penkett, Christopher J., Stephens, Jonathan C., Bogaard, Harm J., Church, Colin, Coghlan, Gerry, Coleman, Anna W., Condliffe, Robin, Eichstaedt, Christina A., Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Girerd, Barbara, Grünig, Ekkehard, Holden, Simon, Howard, Luke, Humbert, Marc, Kiely, David G., Kovacs, Gabor, Lordan, Jim, Machado, Rajiv D., MacKenzie Ross, Robert V., McCabe, Colm, Moledina, Shahin, Montani, David, Olschewski, Horst, Pepke-Zaba, Joanna, Price, Laura, Rhodes, Christopher J., Seeger, Werner, Soubrier, Florent, Suntharalingam, Jay, Toshner, Mark R., Vonk Noordegraaf, Anton, Wharton, John, Wild, James M., Wort, Stephen John, Lawrie, Allan, Wilkins, Martin R., Trembath, Richard C., Shen, Yufeng, Chung, Wendy K., Swift, Andrew J., Nichols, William C., Morrell, Nicholas W., Gräf, Stefan
Publicado 2020