Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity

por Bright, Nicholas A., Davis, Luther J., Luzio, J. Paul
Publicado 2016

Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion

por Connell, James W, Lindon, Catherine, Luzio, J Paul, Reid, Evan
Publicado 2009

Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

por Wartosch, Lena, Günesdogan, Ufuk, Graham, Stephen C., Luzio, J. Paul
Publicado 2015

The Sodium/Proton Exchanger NHE8 Regulates Late Endosomal Morphology and Function

por Lawrence, Scott P., Bright, Nicholas A., Luzio, J. Paul, Bowers, Katherine
Publicado 2010

The Role of Intraorganellar Ca(2+)In Late Endosome–Lysosome Heterotypic Fusion and in the Reformation of Lysosomes from Hybrid Organelles

por Pryor, Paul R., Mullock, Barbara M., Bright, Nicholas A., Gray, Sally R., Luzio, J. Paul
Publicado 2000

A dysfunctional endolysosomal pathway common to two sub-types of demyelinating Charcot–Marie–Tooth disease

por Edgar, James R., Ho, Anita K., Laurá, Matilde, Horvath, Rita, Reilly, Mary M., Luzio, J. Paul, Roberts, Rhys C.
Publicado 2020

Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5

por Edwards, Thomas L., Clowes, Virginia E., Tsang, Hilda T. H., Connell, James W., Sanderson, Christopher M., Luzio, J. Paul, Reid, Evan
Publicado 2009

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

por Sahlender, Daniela A., Roberts, Rhys C., Arden, Susan D., Spudich, Giulietta, Taylor, Marcus J., Luzio, J. Paul, Kendrick-Jones, John, Buss, Folma
Publicado 2005

Organelle tethering, pore formation and SNARE compensation in the late endocytic pathway

por Davis, Luther J., Bright, Nicholas A., Edgar, James R., Parkinson, Michael D. J., Wartosch, Lena, Mantell, Judith, Peden, Andrew A., Luzio, J. Paul
Publicado 2021

Structural Basis of the Intracellular Sorting of the SNARE VAMP7 by the AP3 Adaptor Complex

por Kent, Helen M., Evans, Philip R., Schäfer, Ingmar B., Gray, Sally R., Sanderson, Christopher M., Luzio, J. Paul, Peden, Andrew A., Owen, David J.
Publicado 2012

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

por Schäfer, Ingmar B., Hesketh, Geoffrey G., Bright, Nicholas A., Gray, Sally R., Pryor, Paul R., Evans, Philip R, Luzio, J. Paul, Owen, David J.
Publicado 2012

A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I

por Parkinson, Michael D.J., Piper, Siân C., Bright, Nicholas A., Evans, Jennifer L., Boname, Jessica M., Bowers, Katherine, Lehner, Paul J., Luzio, J. Paul
Publicado 2015

Molecular Basis for the Sorting of the SNARE VAMP7 into Endocytic Clathrin-Coated Vesicles by the ArfGAP Hrb

por Pryor, Paul R., Jackson, Lauren, Gray, Sally R., Edeling, Melissa A., Thompson, Amanda, Sanderson, Christopher M., Evans, Philip R., Owen, David J., Luzio, J. Paul
Publicado 2008

The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling

por Tsang, Hilda T.H., Edwards, Thomas L., Wang, Xinnan, Connell, James W., Davies, Rachel J., Durrington, Hannah J., O'Kane, Cahir J., Luzio, J. Paul, Reid, Evan
Publicado 2009

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

por van den Boomen, Dick J. H., Sienkiewicz, Agata, Berlin, Ilana, Jongsma, Marlieke L. M., van Elsland, Daphne M., Luzio, J. Paul, Neefjes, Jacques J. C., Lehner, Paul J.
Publicado 2020

The lysosomal disease caused by mutant VPS33A

por Pavlova, Elena V, Shatunov, Aleksey, Wartosch, Lena, Moskvina, Alena I, Nikolaeva, Lena E, Bright, Nicholas A, Tylee, Karen L, Church, Heather J, Ballabio, Andrea, Luzio, J Paul, Cox, Timothy M
Publicado 2019

Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A

por Pavlova, Elena V., Lev, Dorit, Michelson, Marina, Yosovich, Keren, Michaeli, Hila Gur, Bright, Nicholas A., Manna, Paul T., Dickson, Veronica Kane, Tylee, Karen L., Church, Heather J., Luzio, J. Paul, Cox, Timothy M.
Publicado 2022

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

por Dennis, Megan K., Delevoye, Cédric, Acosta-Ruiz, Amanda, Hurbain, Ilse, Romao, Maryse, Hesketh, Geoffrey G., Goff, Philip S., Sviderskaya, Elena V., Bennett, Dorothy C., Luzio, J. Paul, Galli, Thierry, Owen, David J., Raposo, Graça, Marks, Michael S.
Publicado 2016

VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface

por Hesketh, Geoffrey G., Pérez-Dorado, Inmaculada, Jackson, Lauren P., Wartosch, Lena, Schäfer, Ingmar B., Gray, Sally R., McCoy, Airlie J., Zeldin, Oliver B., Garman, Elspeth F., Harbour, Michael E., Evans, Philip R., Seaman, Matthew N.J., Luzio, J. Paul, Owen, David J.
Publicado 2014

Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29

por Crawley-Snowdon, Harriet, Yang, Ji-Chun, Zaccai, Nathan R., Davis, Luther J., Wartosch, Lena, Herman, Emily K., Bright, Nicholas A., Swarbrick, James S., Collins, Brett M., Jackson, Lauren P., Seaman, Matthew N. J., Luzio, J. Paul, Dacks, Joel B., Neuhaus, David, Owen, David J.
Publicado 2020