Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer

por Wittkowski, Knut M., Dadurian, Christina, Seybold, Martin P., Kim, Han Sang, Hoshino, Ayuko, Lyden, David
Publicado 2018

Correction: Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer

por Wittkowski, Knut M., Dadurian, Christina, Seybold, Martin P., Kim, Han Sang, Hoshino, Ayuko, Lyden, David
Publicado 2019

Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression

por Parks, Matthew M., Kurylo, Chad M., Dass, Randall A., Bojmar, Linda, Lyden, David, Vincent, C. Theresa, Blanchard, Scott C.
Publicado 2018

Extracellular vesicle– and particle-mediated communication shapes innate and adaptive immune responses

por Pelissier Vatter, Fanny A., Cioffi, Michele, Hanna, Samer J., Castarede, Ines, Caielli, Simone, Pascual, Virginia, Matei, Irina, Lyden, David
Publicado 2021

The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche

por Blavier, Laurence, Nakata, Rie, Neviani, Paolo, Sharma, Khounish, Shimada, Hiroyuki, Benedicto, Aitor, Matei, Irina, Lyden, David, DeClerck, Yves A.
Publicado 2023

Id1 Represses Osteoclast-Dependent Transcription and Affects Bone Formation and Hematopoiesis

por Chan, April S., Jensen, Kristian K., Skokos, Dimitris, Doty, Stephen, Lederman, Hannah K., Kaplan, Rosandra N., Rafii, Shahin, Rivella, Stefano, Lyden, David
Publicado 2009

The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings

por Shor, Ryann E., Dai, Jinxiang, Lee, Sun‐Young, Pisarsky, Laura, Matei, Irina, Lucotti, Serena, Lyden, David, Bissell, Mina J., Ghajar, Cyrus M.
Publicado 2021

Mutation of SIMPLE in Charcot–Marie–Tooth 1C alters production of exosomes

por Zhu, Hong, Guariglia, Sara, Yu, Raymond Y. L., Li, Wenjing, Brancho, Deborah, Peinado, Hector, Lyden, David, Salzer, James, Bennett, Craig, Chow, Chi-Wing
Publicado 2013

Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer

por Choi, Jeesoo, Cho, Ho Yeon, Jeon, Jeongseok, Kim, Kyung-A, Han, Yoon Dae, Ahn, Joong Bae, Wortzel, Inbal, Lyden, David, Kim, Han Sang
Publicado 2022

Vascular Endothelial Growth Factor and Angiopoietin-1 Stimulate Postnatal Hematopoiesis by Recruitment of Vasculogenic and Hematopoietic Stem Cells

por Hattori, Koichi, Dias, Sergio, Heissig, Beate, Hackett, Neil R., Lyden, David, Tateno, Masatoshi, Hicklin, Daniel J., Zhu, Zhenping, Witte, Larry, Crystal, Ronald G., Moore, Malcolm A.S., Rafii, Shahin
Publicado 2001

Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach

por Uryu, Kunihiro, Soplop, Nadine, Sheahan, Timothy P., Catanese, Maria-Teresa, Huynh, Chuong, Pena, John, Boudreau, Nancy, Matei, Irina, Kenific, Candia, Hashimoto, Ayako, Hoshino, Ayuko, Rice, Charles M., Lyden, David
Publicado 2023

Stat3 Mediates Expression of Autotaxin in Breast Cancer

por Azare, Janeen, Doane, Ashley, Leslie, Kenneth, Chang, Qing, Berishaj, Marjan, Nnoli, Jennifer, Mark, Kevin, Al-Ahmadie, Hikmat, Gerald, William, Hassimi, Maryam, Viale, Agnes, Stracke, Mary, Lyden, David, Bromberg, Jacqueline
Publicado 2011

Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration

por Ding, Bi-Sen, Nolan, Daniel J., Butler, Jason M., James, Daylon, Babazadeh, Alexander O., Rosenwaks, Zev, Mittal, Vivek, Kobayashi, Hideki, Shido, Koji, Lyden, David, Sato, Thomas N., Rabbany, Sina Y., Rafii, Shahin
Publicado 2010

The perivascular niche regulates breast tumor dormancy

por Ghajar, Cyrus M., Peinado, Héctor, Mori, Hidetoshi, Matei, Irina R., Evason, Kimberley J., Brazier, Hélène, Almeida, Dena, Koller, Antonius, Hajjar, Katherine A., Stainier, Didier Y.R., Chen, Emily I., Lyden, David, Bissell, Mina J.
Publicado 2013

Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression

por Li, Zhongchi, Low, Vivien, Luga, Valbona, Sun, Janet, Earlie, Ethan, Parang, Bobak, Shobana Ganesh, Kripa, Cho, Sungyun, Endress, Jennifer, Schild, Tanya, Hu, Mengying, Lyden, David, Jin, Wenbing, Guo, Chunjun, Dephoure, Noah, Cantley, Lewis C., Laughney, Ashley M., Blenis, John
Publicado 2022

A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors

por Becher, Oren J., Millard, Nathan E., Modak, Shakeel, Kushner, Brian H., Haque, Sofia, Spasojevic, Ivan, Trippett, Tanya M., Gilheeney, Stephen W., Khakoo, Yasmin, Lyden, David C., De Braganca, Kevin C., Kolesar, Jill M., Huse, Jason T., Kramer, Kim, Cheung, Nai-Kong V., Dunkel, Ira J.
Publicado 2017

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

por Sansone, Pasquale, Savini, Claudia, Kurelac, Ivana, Chang, Qing, Amato, Laura Benedetta, Strillacci, Antonio, Stepanova, Anna, Iommarini, Luisa, Mastroleo, Chiara, Daly, Laura, Galkin, Alexander, Thakur, Basant Kumar, Soplop, Nadine, Uryu, Kunihiro, Hoshino, Ayuko, Norton, Larry, Bonafé, Massimiliano, Cricca, Monica, Gasparre, Giuseppe, Lyden, David, Bromberg, Jacqueline
Publicado 2017

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

por Thakur, Basant Kumar, Zhang, Haiying, Becker, Annette, Matei, Irina, Huang, Yujie, Costa-Silva, Bruno, Zheng, Yan, Hoshino, Ayuko, Brazier, Helene, Xiang, Jenny, Williams, Caitlin, Rodriguez-Barrueco, Ruth, Silva, Jose M, Zhang, Weijia, Hearn, Stephen, Elemento, Olivier, Paknejad, Navid, Manova-Todorova, Katia, Welte, Karl, Bromberg, Jacqueline, Peinado, Héctor, Lyden, David
Publicado 2014

Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation

por Papaspyridonos, Marianna, Matei, Irina, Huang, Yujie, do Rosario Andre, Maria, Brazier-Mitouart, Helene, Waite, Janelle C., Chan, April S., Kalter, Julie, Ramos, Ilyssa, Wu, Qi, Williams, Caitlin, Wolchok, Jedd D., Chapman, Paul B., Peinado, Hector, Anandasabapathy, Niroshana, Ocean, Allyson J., Kaplan, Rosandra N., Greenfield, Jeffrey P., Bromberg, Jacqueline, Skokos, Dimitris, Lyden, David
Publicado 2015

Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain

por Dai, Jinxiang, Cimino, Patrick J., Gouin, Kenneth H., Grzelak, Candice A., Barrett, Alexander, Lim, Andrea R., Long, Annalyssa, Weaver, Stephanie, Saldin, Lindsey T., Uzamere, Aiyedun, Schulte, Vera, Clegg, Nigel, Pisarsky, Laura, Lyden, David, Bissell, Mina J., Knott, Simon, Welm, Alana L., Bielas, Jason H., Hansen, Kirk C., Winkler, Frank, Holland, Eric C., Ghajar, Cyrus M.
Publicado 2022