Lipidomics unveils the complexity of the lipidome in metabolic diseases

por Lydic, Todd A., Goo, Young-Hwa
Publicado 2018

Cholesterol Acceptors Regulate the Lipidome of Macrophage Foam Cells

por Paul, Antoni, Lydic, Todd A., Hogan, Ryan, Goo, Young-Hwa
Publicado 2019

BSCL2/Seipin deficiency in hearts causes cardiac energy deficit and dysfunction via inducing excessive lipid catabolism

por Zhou, Hongyi, Li, Jie, Su, Huabo, Li, Ji, Lydic, Todd A., Young, Martin E, Chen, Weiqin
Publicado 2022

Altered Lipid Metabolism in Residual White Adipose Tissues of Bscl2 Deficient Mice

por Chen, Weiqin, Zhou, Hongyi, Liu, Siyang, Fhaner, Cassie J., Gross, Bethany C., Lydic, Todd A., Reid, Gavin E.
Publicado 2013

Pediatric Multi-Organ Dysfunction Syndrome: Analysis by an Untargeted “Shotgun” Lipidomic Approach Reveals Low-Abundance Plasma Phospholipids and Dynamic Recovery over 8-Day Period...

por Leimanis-Laurens, Mara L., Ferguson, Karen, Wolfrum, Emily, Boville, Brian, Sanfilippo, Dominic, Lydic, Todd A., Prokop, Jeremy W., Rajasekaran, Surender
Publicado 2021

Hexosylceramides and Glycerophosphatidylcholine GPC(36:1) Increase in Multi-Organ Dysfunction Syndrome Patients with Pediatric Intensive Care Unit Admission over 8-Day Hospitalizat...

por Leimanis-Laurens, Mara, Wolfrum, Emily, Ferguson, Karen, Grunwell, Jocelyn R., Sanfilippo, Dominic, Prokop, Jeremy W., Lydic, Todd A., Rajasekaran, Surender
Publicado 2021

Novel Liposomal Rolipram Formulation for Clinical Application to Reduce Emesis

por Gobejishvili, Leila, Rodriguez, Walter E, Bauer, Philip, Wang, Yali, Soni, Chirag, Lydic, Todd, Barve, Shirish, McClain, Craig, Maldonado, Claudio
Publicado 2022

The Feasibility of Studying Metabolites in PICU Multi-Organ Dysfunction Syndrome Patients over an 8-Day Course Using an Untargeted Approach

por Leimanis-Laurens, Mara, Gil, Danny, Kampfschulte, Andrew, Krohn, Claire, Prentice, Elizabeth, Sanfilippo, Dominic, Prokop, Jeremy W., Lydic, Todd A., Rajasekaran, Surender
Publicado 2021

Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes

por Levitsky, Yan, Hammer, Sandra S., Fisher, Kiera P., Huang, Chao, Gentles, Travan L., Pegouske, David J., Xi, Caimin, Lydic, Todd A., Busik, Julia V., Proshlyakov, Denis A.
Publicado 2020

ER stress and lipid imbalance drive embryonic cardiomyopathy in a human heart organoid model of pregestational diabetes

por Kostina, Aleksandra, Lewis-Israeli, Yonatan R., Abdelhamid, Mishref, Gabalski, Mitchell A., Volmert, Brett D., Lankerd, Haley, Huang, Amanda R., Wasserman, Aaron H., Lydic, Todd, Chan, Christina, Olomu, Isoken, Aguirre, Aitor
Publicado 2023

Remodeling of Retinal Fatty Acids in an Animal Model of Diabetes: A Decrease in Long-Chain Polyunsaturated Fatty Acids Is Associated With a Decrease in Fatty Acid Elongases Elovl2...

por Tikhonenko, Maria, Lydic, Todd A., Wang, Yun, Chen, Weiqin, Opreanu, Madalina, Sochacki, Andrew, McSorley, Kelly M., Renis, Rebecca L., Kern, Timothy, Jump, Donald B., Reid, Gavin E., Busik, Julia V.
Publicado 2010

Changes in the Daily Rhythm of Lipid Metabolism in the Diabetic Retina

por Wang, Qi, Tikhonenko, Maria, Bozack, Svetlana N., Lydic, Todd A., Yan, Lily, Panchy, Nicholas L., Mcsorley, Kelly M., Faber, Matthew S., Yan, Yuanqing, Boulton, Michael E., Grant, Maria B., Busik, Julia V.
Publicado 2014

Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy

por Wang, Qi, Navitskaya, Svetlana, Chakravarthy, Harshini, Huang, Chao, Kady, Nermin, Lydic, Todd A., Chen, Y. Eugene, Yin, Ke-Jie, Powell, Folami Lamoke, Martin, Pamela M., Grant, Maria B., Busik, Julia V.
Publicado 2016

The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor

por Hammer, Sandra S., Beli, Eleni, Kady, Nermin, Wang, Qi, Wood, Kiana, Lydic, Todd A., Malek, Goldis, Saban, Daniel R., Wang, Xiaoxin X., Hazra, Sugata, Levi, Moshe, Busik, Julia V., Grant, Maria B.
Publicado 2017

The Unconventional Role of Acid Sphingomyelinase in Regulation of Retinal Microangiopathy in Diabetic Human and Animal Models

por Opreanu, Madalina, Tikhonenko, Maria, Bozack, Svetlana, Lydic, Todd A., Reid, Gavin E., McSorley, Kelly M., Sochacki, Andrew, Perez, Gloria I., Esselman, Walter J., Kern, Timothy, Kolesnick, Richard, Grant, Maria B., Busik, Julia V.
Publicado 2011

N-3 Polyunsaturated Fatty Acids Prevent Diabetic Retinopathy by Inhibition of Retinal Vascular Damage and Enhanced Endothelial Progenitor Cell Reparative Function

por Tikhonenko, Maria, Lydic, Todd A., Opreanu, Madalina, Li Calzi, Sergio, Bozack, Svetlana, McSorley, Kelly M., Sochacki, Andrew L., Faber, Matthew S., Hazra, Sugata, Duclos, Shane, Guberski, Dennis, Reid, Gavin E., Grant, Maria B., Busik, Julia V.
Publicado 2013

Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice

por Zelows, Mikala M., Cady, Corissa, Dharanipragada, Nikitha, Mead, Anna E., Kipp, Zachary A., Bates, Evelyn A., Varadharajan, Venkateshwari, Banerjee, Rakhee, Park, Se-Hyung, Shelman, Nathan R., Clarke, Harrison A., Hawkinson, Tara R., Medina, Terrymar, Sun, Ramon C., Lydic, Todd A., Hinds, Terry D., Brown, J. Mark, Softic, Samir, Graf, Gregory A., Helsley, Robert N.
Publicado 2023

Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function

por Yang, Zhi-Hong, Gorusupudi, Aruna, Lydic, Todd A., Mondal, Anupam K., Sato, Seizo, Yamazaki, Isao, Yamaguchi, Hideaki, Tang, Jingrong, Rojulpote, Krishna Vamsi, Lin, Anna B., Decot, Hannah, Koch, Hannah, Brock, Daniel C., Arunkumar, Ranganathan, Shi, Zhen-Dan, Yu, Zu-Xi, Pryor, Milton, Kun, Julia F., Swenson, Rolf E., Swaroop, Anand, Bernstein, Paul S., Remaley, Alan T.
Publicado 2023