Dehydroamino acid chemical biology: an example of functional group interconversion on proteins

por Jones, Lyn H.
Publicado 2020

Sulfonyl fluorides as privileged warheads in chemical biology

por Narayanan, Arjun, Jones, Lyn H.
Publicado 2015

A Cross-Species Study of Gesture and Its Role in Symbolic Development: Implications for the Gestural Theory of Language Evolution

por Gillespie-Lynch, K., Greenfield, P. M., Feng, Y., Savage-Rumbaugh, S., Lyn, H.
Publicado 2013

Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane

por Clulow, James A., Storck, Elisabeth M., Lanyon-Hogg, Thomas, Kalesh, Karunakaran A., Jones, Lyn H., Tate, Edward W.
Publicado 2017

Fragment-based covalent ligand discovery

por Lu, Wenchao, Kostic, Milka, Zhang, Tinghu, Che, Jianwei, Patricelli, Matthew P., Jones, Lyn H., Chouchani, Edward T., Gray, Nathanael S.
Publicado 2021

Correction: Fragment-based covalent ligand discovery

por Lu, Wenchao, Kostic, Milka, Zhang, Tinghu, Che, Jianwei, Patricelli, Matthew P., Jones, Lyn H., Chouchani, Edward T., Gray, Nathanael S.
Publicado 2021

Synthetic Phosphorylation of p38α Recapitulates Protein Kinase Activity

por Chooi, K. Phin, Galan, Sébastien R. G., Raj, Ritu, McCullagh, James, Mohammed, Shabaz, Jones, Lyn H., Davis, Benjamin G.
Publicado 2014

A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I

por Zhang, Fan, Bodycombe, Nicole E., Haskell, Keith M., Sun, Yumei L., Wang, Eric T., Morris, Carl A., Jones, Lyn H., Wood, Lauren D., Pletcher, Mathew T.
Publicado 2017

Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead

por Nowak, Radosław P., Ragosta, Leah, Huerta, Fidel, Liu, Hu, Ficarro, Scott B., Cruite, Justin T., Metivier, Rebecca J., Donovan, Katherine A., Marto, Jarrod A., Fischer, Eric S., Zerfas, Breanna L., Jones, Lyn H.
Publicado 2023

Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium

por Porter, James D., Watson, Jennifer, Roberts, Lee R., Gill, Simren K., Groves, Helen, Dhariwal, Jaideep, Almond, Mark H., Wong, Ernie, Walton, Ross P., Jones, Lyn H., Tregoning, John, Kilty, Iain, Johnston, Sebastian L., Edwards, Michael R.
Publicado 2016

A mild synthesis of N-functionalised bromomaleimides, thiomaleimides and bromopyridazinediones()

por Castañeda, Lourdes, Wright, Zoë V.F., Marculescu, Cristina, Tran, Trang M., Chudasama, Vijay, Maruani, Antoine, Hull, Elizabeth A., Nunes, João P.M., Fitzmaurice, Richard J., Smith, Mark E.B., Jones, Lyn H., Caddick, Stephen, Baker, James R.
Publicado 2013

Cereblon covalent modulation through structure-based design of histidine targeting chemical probes

por Cruite, Justin T., Dann, Geoffrey P., Che, Jianwei, Donovan, Katherine A., Ferrao, Silas, Ficarro, Scott B., Fischer, Eric S., Gray, Nathanael S., Huerta, Fidel, Kong, Nikki R., Liu, Hu, Marto, Jarrod A., Metivier, Rebecca J., Nowak, Radosław P., Zerfas, Breanna L., Jones, Lyn H.
Publicado 2022

Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice

por Pryde, David C., Jones, Lyn H., Gervais, David P., Stead, David R., Blakemore, David C., Selby, Matthew D., Brown, Alan D., Coe, Jotham W., Badland, Matthew, Beal, David M., Glen, Rebecca, Wharton, Yvonne, Miller, Gavin J., White, Phil, Zhang, Ningli, Benoit, Michelle, Robertson, Karen, Merson, James R., Davis, Heather L., McCluskie, Michael J.
Publicado 2013

Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation

por Huang, Xuan, Roet, Kasper C.D., Zhang, Liying, Brault, Amy, Berg, Allison P., Jefferson, Anne B., Klug-McLeod, Jackie, Leach, Karen L., Vincent, Fabien, Yang, Hongying, Coyle, Anthony J., Jones, Lyn H., Frost, Devlin, Wiskow, Ole, Chen, Kuchuan, Maeda, Rie, Grantham, Alyssa, Dornon, Mary K., Klim, Joseph R., Siekmann, Marco T., Zhao, Dongyi, Lee, Seungkyu, Eggan, Kevin, Woolf, Clifford J.
Publicado 2021

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

por Cherry, Jonathan J., DiDonato, Christine J., Androphy, Elliot J., Calo, Alessandro, Potter, Kyle, Custer, Sara K., Du, Sarah, Foley, Timothy L., Gopalsamy, Ariamala, Reedich, Emily J., Gordo, Susana M., Gordon, William, Hosea, Natalie, Jones, Lyn H., Krizay, Daniel K., LaRosa, Gregory, Li, Hongxia, Mathur, Sachin, Menard, Carol A., Patel, Paraj, Ramos-Zayas, Rebeca, Rietz, Anne, Rong, Haojing, Zhang, Baohong, Tones, Michael A.
Publicado 2017

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

por Liu, Shenping, Dakin, Leslie A., Xing, Li, Withka, Jane M., Sahasrabudhe, Parag V., Li, Wei, Banker, Mary Ellen, Balbo, Paul, Shanker, Suman, Chrunyk, Boris A., Guo, Zuojun, Chen, Jinshan M., Young, Jennifer A., Bai, Guoyun, Starr, Jeremy T., Wright, Stephen W., Bussenius, Joerg, Tan, Sheng, Gopalsamy, Ariamala, Lefker, Bruce A., Vincent, Fabien, Jones, Lyn H., Xu, Hua, Hoth, Lise R., Geoghegan, Kieran F., Qiu, Xiayang, Bunnage, Mark E., Thorarensen, Atli
Publicado 2016