Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments

por Lynch, Eric M., Kollman, Justin M.
Publicado 2019

Activation of the γ-Tubulin Complex by the Mto1/2 Complex

por Lynch, Eric M., Groocock, Lynda M., Borek, Weronika E., Sawin, Kenneth E.
Publicado 2014

Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore

por Bao, Xun X, Spanos, Christos, Kojidani, Tomoko, Lynch, Eric M, Rappsilber, Juri, Hiraoka, Yasushi, Haraguchi, Tokuko, Sawin, Kenneth E
Publicado 2018

Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation

por Hansen, Jesse M, Horowitz, Avital, Lynch, Eric M, Farrell, Daniel P, Quispe, Joel, DiMaio, Frank, Kollman, Justin M
Publicado 2021

CTP synthase polymerization in germline cells of the developing Drosophila egg supports egg production

por Simonet, Jacqueline C., Foster, Maya J., Lynch, Eric M., Kollman, Justin M., Nicholas, Emmanuelle, O'Reilly, Alana M., Peterson, Jeffrey R.
Publicado 2020

Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1

por Leong, Su Ling, Lynch, Eric M., Zou, Juan, Tay, Ye Dee, Borek, Weronika E., Tuijtel, Maarten W., Rappsilber, Juri, Sawin, Kenneth E.
Publicado 2023

Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1

por Leong, Su Ling, Lynch, Eric M., Zou, Juan, Tay, Ye Dee, Borek, Weronika E., Tuijtel, Maarten W., Rappsilber, Juri, Sawin, Kenneth E.
Publicado 2019

Human CTP synthase filament structure reveals the active enzyme conformation

por Lynch, Eric M., Hicks, Derrick R., Shepherd, Matthew, Endrizzi, James A., Maker, Allison, Hansen, Jesse M., Barry, Rachael M., Gitai, Zemer, Baldwin, Enoch P., Kollman, Justin M.
Publicado 2017

Selective activation of PFKL suppresses the phagocytic oxidative burst

por Amara, Neri, Cooper, Madison P., Voronkova, Maria A., Webb, Bradley A., Lynch, Eric M., Kollman, Justin M., Ma, Taylur, Yu, Kebing, Lai, Zijuan, Sangaraju, Dewakar, Kayagaki, Nobuhiko, Newton, Kim, Bogyo, Matthew, Staben, Steven T., Dixit, Vishva M.
Publicado 2021

Structural basis for isoform-specific inhibition of human CTPS1

por Lynch, Eric M., DiMattia, Michael A., Albanese, Steven, van Zundert, Gydo C. P., Hansen, Jesse M., Quispe, Joel D., Kennedy, Madison A., Verras, Andreas, Borrelli, Kenneth, Toms, Angela V., Kaila, Neelu, Kreutter, Kevin D., McElwee, Joshua J., Kollman, Justin M.
Publicado 2021

Multimeric antibodies from antigen-specific human IgM(+) memory B cells restrict Plasmodium parasites

por Thouvenel, Christopher D., Fontana, Mary F., Netland, Jason, Krishnamurty, Akshay T., Takehara, Kennidy K., Chen, Yu, Singh, Suruchi, Miura, Kazutoyo, Keitany, Gladys J., Lynch, Eric M., Portugal, Silvia, Miranda, Marcos C., King, Neil P., Kollman, Justin M., Crompton, Peter D., Long, Carole A., Pancera, Marie, Rawlings, David J., Pepper, Marion
Publicado 2021