Increasing the Complexity of Organoid Cultures: Current Status and Future Challenges

por Lynch, John P.
Publicado 2019

Organoids and Engineered Organ Systems

por Samuelson, Linda C., Lynch, John P.
Publicado 2019

Ectopic Cdx2 Expression in Murine Esophagus Models an Intermediate Stage in the Emergence of Barrett's Esophagus

por Kong, Jianping, Crissey, Mary Ann, Funakoshi, Shinsuke, Kreindler, James L., Lynch, John P.
Publicado 2011

GUCY2C maintains intestinal LGR5(+) stem cells by opposing ER stress

por Kraft, Crystal L., Rappaport, Jeffrey A., Snook, Adam E., Pattison, Amanda M., Lynch, John P., Waldman, Scott A.
Publicado 2017

Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems

por Hartman, Kira G, Bortner, James D, Falk, Gary W, Yu, Jian, Martín, Martín G, Rustgi, Anil K, Lynch, John P
Publicado 2013

Cdx1 and c-Myc Foster the Initiation of Transdifferentiation of the Normal Esophageal Squamous Epithelium toward Barrett's Esophagus

por Stairs, Douglas B., Nakagawa, Hiroshi, Klein-Szanto, Andres, Mitchell, Shukriyyah D., Silberg, Debra G., Tobias, John W., Lynch, John P., Rustgi, Anil K.
Publicado 2008

KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF

por Shaverdashvili, Khvaramze, Padlo, Jennie, Weinblatt, Daniel, Jia, Yang, Jiang, Wenpeng, Rao, Divya, Laczkó, Dorottya, Whelan, Kelly A., Lynch, John P., Muir, Amanda B., Katz, Jonathan P.
Publicado 2019

Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche

por Yang, Ting-Lin B., Chen, Qijun, Deng, Jennifer T., Jagannathan, Geetha, Tobias, John W., Schultz, David C., Wang, Shan, Lengner, Christopher J., Rustgi, Anil K., Lynch, John P., Johnson, F. Brad
Publicado 2017

Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia

por Kong, Jianping, Sai, Hong, Crissey, Mary Ann S., Jhala, Nirag, Falk, Gary W., Ginsberg, Gregory G., Abrams, Julian A., Nakagawa, Hiroshi, Wang, Kenneth, Rustgi, Anil K., Wang, Timothy C., Lynch, John P.
Publicado 2015

Maintenance Golimumab Treatment in Pediatric UC Patients With Moderately to Severely Active UC: PURSUIT PEDS PK Long-Term Study Results

por Hyams, Jeffrey S, O’Brien, Christopher D, Padgett, Lakshmi, Rosh, Joel R, Turner, Dan, Veereman, Genevieve, Griffiths, Anne M, Heyman, Melvin B, Wahbeh, Ghassan, Adedokun, Omoniyi J, Strauss, Richard S, Lynch, John P, Chan, Daphne
Publicado 2020