Advances in Non-Animal Testing Approaches towards Accelerated Clinical Translation of Novel Nanotheranostic Therapeutics for Central Nervous System Disorders

por Lynch, Mark J., Gobbo, Oliviero L.
Publicado 2021

Synergy Assessment of Four Antimicrobial Bioactive Compounds for the Combinational Treatment of Bacterial Pathogens

por Masterson, Kevin, Major, Ian, Lynch, Mark, Rowan, Neil
Publicado 2023

Role of Gastrografin in Patients With Small Bowel Obstruction

por Almafreji, Ibrahim, Chinaka, Ugochukwu, Hussain, Amir, Lynch, Mark, Cottrell, Richard
Publicado 2020

VKORC1 sequence variants associated with resistance to anticoagulant rodenticides in Irish populations of Rattus norvegicus and Mus musculus domesticus

por Mooney, Jean, Lynch, Mark R., Prescott, Colin V., Clegg, Tracy, Loughlin, Michael, Hannon, Bernard, Moore, Colm, Faulkner, Richard
Publicado 2018

Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements

por Furlan, Cristina, Dirks, René A. M., Thomas, Peter C., Jones, Robert C., Wang, Jing, Lynch, Mark, Marks, Hendrik, Vermeulen, Michiel
Publicado 2019

Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions

por Morgan, Claire C, Shakya, Kabita, Webb, Andrew, Walsh, Thomas A, Lynch, Mark, Loscher, Christine E, Ruskin, Heather J, O’Connell, Mary J
Publicado 2012

β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects — Implications for coro...

por Murphy, Emma J., Masterson, Claire, Rezoagli, Emanuele, O'Toole, Daniel, Major, Ian, Stack, Gary D., Lynch, Mark, Laffey, John G., Rowan, Neil J.
Publicado 2020

Pharmacokinetics and Safety of Elotuzumab Combined With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma and Various Levels of Renal Impairment: Results of a Phase...

por Berdeja, Jesus, Jagannath, Sundar, Zonder, Jeffrey, Badros, Ashraf, Kaufman, Jonathan L., Manges, Robert, Gupta, Manish, Tendolkar, Amol, Lynch, Mark, Bleickardt, Eric, Paliwal, Prashni, Vij, Ravi
Publicado 2015

Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion

por Cheepala, Satish B, Yin, Weihong, Syed, Zanobia, Gill, Jennifer N, McMillian, Alaina, Kleiner, Heather E, Lynch, Mark, Loganantharaj, Rasiah, Trutschl, Marjan, Cvek, Urska, Clifford, John L
Publicado 2009

Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response

por Lynch, Mark, Walsh, Thomas A., Marszalowska, Izabela, Webb, Andrew E., MacAogain, Micheál, Rogers, Thomas R., Windle, Henry, Kelleher, Dermot, O’Connell, Mary J., Loscher, Christine E.
Publicado 2017

Erratum to: Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response

por Lynch, Mark, Walsh, Thomas A., Marszalowska, Izabela, Webb, Andrew E., Mac Aogáin, Micheál, Rogers, Thomas R., Windle, Henry, Kelleher, Dermot, O’Connell, Mary J., Loscher, Christine E.
Publicado 2017

Elotuzumab monotherapy in patients with smouldering multiple myeloma: a phase 2 study

por Jagannath, Sundar, Laubach, Jacob, Wong, Ellice, Stockerl‐Goldstein, Keith, Rosenbaum, Cara, Dhodapkar, Madhav, Jou, Ying‐Ming, Lynch, Mark, Robbins, Michael, Shelat, Suresh, Anderson, Kenneth C., Richardson, Paul G.
Publicado 2018

Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular proximity and gene regulation

por Flores, Bianca C. T., Chawla, Smriti, Ma, Ning, Sanada, Chad, Kujur, Praveen Kumar, Yeung, Rudy, Bellon, Margot B., Hukari, Kyle, Fowler, Brian, Lynch, Mark, Chinen, Ludmilla T. D., Ramalingam, Naveen, Sengupta, Debarka, Jeffrey, Stefanie S.
Publicado 2022

The nature and nurture of cell heterogeneity: accounting for macrophage gene-environment interactions with single-cell RNA-Seq

por Wills, Quin F., Mellado-Gomez, Esther, Nolan, Rory, Warner, Damien, Sharma, Eshita, Broxholme, John, Wright, Benjamin, Lockstone, Helen, James, William, Lynch, Mark, Gonzales, Michael, West, Jay, Leyrat, Anne, Padilla-Parra, Sergi, Filippi, Sarah, Holmes, Chris, Moore, Michael D., Bowden, Rory
Publicado 2017

Nivolumab treatment beyond RECIST‐defined progression in recurrent or metastatic squamous cell carcinoma of the head and neck in CheckMate 141: A subgroup analysis of a randomized...

por Haddad, Robert, Concha‐Benavente, Fernando, Blumenschein, George, Fayette, Jerome, Guigay, Joel, Colevas, A. Dimitrios, Licitra, Lisa, Kasper, Stefan, Vokes, Everett E., Worden, Francis, Saba, Nabil F., Tahara, Makoto, Jayaprakash, Vijayvel, Lynch, Mark, Li, Li, Gillison, Maura L., Harrington, Kevin J., Ferris, Robert L.
Publicado 2019

A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins

por Ryan, Anthony, Lynch, Mark, Smith, Sinead M., Amu, Sylvie, Nel, Hendrik J., McCoy, Claire E., Dowling, Jennifer K., Draper, Eve, O'Reilly, Vincent, McCarthy, Ciara, O'Brien, Julie, Ní Eidhin, Déirdre, O'Connell, Mary J., Keogh, Brian, Morton, Charles O., Rogers, Thomas R., Fallon, Padraic G., O'Neill, Luke A., Kelleher, Dermot, Loscher, Christine E.
Publicado 2011

Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia

por Turati, Virginia A., Guerra-Assunção, José Afonso, Potter, Nicola E., Gupta, Rajeev, Ecker, Simone, Daneviciute, Agne, Tarabichi, Maxime, Webster, Amy P., Ding, Chuling, May, Gillian, James, Chela, Brown, John, Conde, Lucia, Russell, Lisa J., Ancliff, Phil, Inglott, Sarah, Cazzaniga, Giovanni, Biondi, Andrea, Hall, Georgina W., Lynch, Mark, Hubank, Mike, Macaulay, Iain, Beck, Stephan, Van Loo, Peter, Jacobsen, Sten E., Greaves, Mel, Herrero, Javier, Enver, Tariq
Publicado 2021