Noncoding RNAs

por Hardikar, Anandwardhan A., Walker, Michael D., Lynn, Francis
Publicado 2012

Friend and foe: β-cell Ca(2+) signaling and the development of diabetes

por Sabatini, Paul V., Speckmann, Thilo, Lynn, Francis C.
Publicado 2018

TALEN/CRISPR-Mediated eGFP Knock-In Add-On at the OCT4 Locus Does Not Impact Differentiation of Human Embryonic Stem Cells towards Endoderm

por Krentz, Nicole A. J., Nian, Cuilan, Lynn, Francis C.
Publicado 2014

Identification of the bHLH Factor Math6 as a Novel Component of the Embryonic Pancreas Transcriptional Network

por Lynn, Francis C., Sanchez, Lidia, Gomis, Ramon, German, Michael S., Gasa, Rosa
Publicado 2008

Regulation of GIP and GLP1 Receptor Cell Surface Expression by N-Glycosylation and Receptor Heteromerization

por Whitaker, Gina M., Lynn, Francis C., McIntosh, Christopher H. S., Accili, Eric A.
Publicado 2012

Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8)

por Ejarque, Miriam, Mir-Coll, Joan, Gomis, Ramon, German, Michael S., Lynn, Francis C., Gasa, Rosa
Publicado 2016

Maintenance of β-Cell Maturity and Plasticity in the Adult Pancreas: Developmental Biology Concepts in Adult Physiology

por Szabat, Marta, Lynn, Francis C., Hoffman, Brad G., Kieffer, Timothy J., Allan, Douglas W., Johnson, James D.
Publicado 2012

Retraction Note: Calcium-dependent transcriptional changes in human pancreatic islet cells reveal functional diversity in islet cell subtypes

por Yoon, Ji Soo, Sasaki, Shugo, Velghe, Jane, Lee, Michelle Y. Y., Winata, Helena, Nian, Cuilan, Lynn, Francis C.
Publicado 2023

A mouse model for monitoring islet cell genesis and developing therapies for diabetes

por Shimajiri, Yoshinori, Kosaka, Yasuhiro, Scheel, David W., Lynn, Francis C., Kishimoto, Nina, Wang, Juehu, Zhao, Shuhong, German, Michael S.
Publicado 2011

RETRACTED ARTICLE: Calcium-dependent transcriptional changes in human pancreatic islet cells reveal functional diversity in islet cell subtypes

por Yoon, Ji Soo, Sasaki, Shugo, Velghe, Jane, Lee, Michelle Y. Y., Winata, Helena, Nian, Cuilan, Lynn, Francis C.
Publicado 2022

Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5

por Sasaki, Shugo, Nian, Cuilan, Xu, Eric E., Pasula, Daniel J., Winata, Helena, Grover, Sanya, Luciani, Dan S., Lynn, Francis C.
Publicado 2023

Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

por Vanderkruk, Ben, Maeshima, Nina, Pasula, Daniel J., An, Meilin, McDonald, Cassandra L., Suresh, Priya, Luciani, Dan S., Lynn, Francis C., Hoffman, Brad G.
Publicado 2023

Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors

por Krentz, Nicole A.J., Lee, Michelle Y.Y., Xu, Eric E., Sproul, Shannon L.J., Maslova, Alexandra, Sasaki, Shugo, Lynn, Francis C.
Publicado 2018

Islet amyloid polypeptide does not suppress pancreatic cancer

por Taylor, Austin J., Panzhinskiy, Evgeniy, Orban, Paul C., Lynn, Francis C., Schaeffer, David F., Johnson, James D., Kopp, Janel L., Verchere, C. Bruce
Publicado 2023

Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells

por Sabatini, Paul V., Krentz, Nicole A.J., Zarrouki, Bader, Westwell-Roper, Clara Y., Nian, Cuilan, Uy, Ryan A., Shapiro, A.M. James, Poitout, Vincent, Lynn, Francis C.
Publicado 2013

In silico discovery of small molecules for efficient stem cell differentiation into definitive endoderm

por Novakovsky, Gherman, Sasaki, Shugo, Fornes, Oriol, Omur, Meltem E., Huang, Helen, Bayly, Carmen L., Zhang, Dahai, Lim, Nathaniel, Cherkasov, Artem, Pavlidis, Paul, Mostafavi, Sara, Lynn, Francis C., Wasserman, Wyeth W.
Publicado 2023

A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells

por Deen, Matthew C., Zhu, Yanping, Gros, Christina, Na, Na, Gilormini, Pierre-André, Shen, David L., Bhosale, Sandeep, Anastasi, Nadia, Wang, RuiQi, Shan, Xiaoyang, Harde, Eva, Jagasia, Ravi, Lynn, Francis C., Vocadlo, David J.
Publicado 2022

Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans

por Shomer, Naomi, Kadhim, Alexandre Zacharie, Grants, Jennifer Margaret, Cheng, Xuanjin, Alhusari, Deema, Bhanshali, Forum, Poon, Amy Fong-Yuk, Lee, Michelle Ying Ya, Muhuri, Anik, Park, Jung In, Shih, James, Lee, Dongyeop, Lee, Seung-Jae V., Lynn, Francis Christopher, Taubert, Stefan
Publicado 2019

Serotonin Regulates Pancreatic β-Cell Mass during Pregnancy

por Kim, Hail, Toyofuku, Yukiko, Lynn, Francis C., Chak, Eric, Uchida, Toyoyoshi, Mizukami, Hirok i, Fujitani, Yoshio, Kawamori, Ryuzo, Miyatsuka, Takeshi, Kosaka, Yasuhiro, Yang, Katherine, Honig, Gerard, van der Hart, Marieke, Kishimoto, Nina, Wang, Juehu, Yagihashi, Soroku, Tecott, Laurence H., Watada, Hirotaka, German, Michael S.
Publicado 2010

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

por Frew, Jonathan, Baradaran-Heravi, Alireza, Balgi, Aruna D., Wu, Xiujuan, Yan, Tyler D., Arns, Steve, Shidmoossavee, Fahimeh S., Tan, Jason, Jaquith, James B., Jansen-West, Karen R., Lynn, Francis C., Gao, Fen-Biao, Petrucelli, Leonard, Feldman, Howard H., Mackenzie, Ian R., Roberge, Michel, Nygaard, Haakon B.
Publicado 2020