Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs

por Finnigan, John P., Newman, Jenna H., Patskovsky, Yury, Patskovska, Larysa, Ishizuka, Andrew S., Lynn, Geoffrey M., Seder, Robert A., Krogsgaard, Michelle, Bhardwaj, Nina
Publicado 2023

Therapeutic cancer vaccines for pediatric malignancies: advances, challenges, and emerging technologies

por Olsen, Hannah E, Lynn, Geoffrey M, Valdes, Pablo A, Cerecedo Lopez, Christian D, Ishizuka, Andrew S, Arnaout, Omar, Bi, W Linda, Peruzzi, Pier Paolo, Chiocca, E Antonio, Friedman, Gregory K, Bernstock, Joshua D
Publicado 2021

Oncolytic Herpes Simplex Virus Immunotherapy for Brain Tumors: Current Pitfalls and Emerging Strategies to Overcome Therapeutic Resistance

por Totsch, Stacie K., Schlappi, Charles, Kang, Kyung-Don, Ishizuka, Andrew S., Lynn, Geoffrey M., Fox, Brandon, Beierle, Elizabeth A., Whitley, Richard J, Markert, James M., Gillespie, G. Yancey, Bernstock, Joshua D., Friedman, Gregory K.
Publicado 2019

Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

por Ramirez-Valdez, Ramiro A., Baharom, Faezzah, Khalilnezhad, Ahad, Fussell, Sloane C., Hermans, Dalton J., Schrager, Alexander M., Tobin, Kennedy K.S., Lynn, Geoffrey M., Khalilnezhad, Shabnam, Ginhoux, Florent, Van den Eynde, Benoit J., Leung, Carol Sze Ki, Ishizuka, Andrew S., Seder, Robert A.
Publicado 2023

Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates

por Francica, Joseph R., Laga, Richard, Lynn, Geoffrey M., Mužíková, Gabriela, Androvič, Ladislav, Aussedat, Baptiste, Walkowicz, William E., Padhan, Kartika, Ramirez-Valdez, Ramiro Andrei, Parks, Robert, Schmidt, Stephen D., Flynn, Barbara J., Tsybovsky, Yaroslav, Stewart-Jones, Guillaume B. E., Saunders, Kevin O., Baharom, Faezzah, Petrovas, Constantinos, Haynes, Barton F., Seder, Robert A.
Publicado 2019

Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy

por Zhu, Guizhi, Lynn, Geoffrey M., Jacobson, Orit, Chen, Kai, Liu, Yi, Zhang, Huimin, Ma, Ying, Zhang, Fuwu, Tian, Rui, Ni, Qianqian, Cheng, Siyuan, Wang, Zhantong, Lu, Nan, Yung, Bryant C., Wang, Zhe, Lang, Lixin, Fu, Xiao, Jin, Albert, Weiss, Ido D., Vishwasrao, Harshad, Niu, Gang, Shroff, Hari, Klinman, Dennis M., Seder, Robert A., Chen, Xiaoyuan
Publicado 2017

Intravenous Nanoparticle Vaccination Generates Stem-Like TCF1(+) Neoantigen-Specific CD8(+) T Cells

por Baharom, Faezzah, Ramirez-Valdez, Ramiro A, Tobin, Kennedy KS, Yamane, Hidehiro, Dutertre, Charles-Antoine, Khalilnezhad, Ahad, Reynoso, Glennys V, Coble, Vincent L, Lynn, Geoffrey M, Mulè, Matthew P, Martins, Andrew J, Finnigan, John P, Zhang, Xiao Meng, Hamerman, Jessica A, Bhardwaj, Nina, Tsang, John S, Hickman, Heather D, Ginhoux, Florent, Ishizuka, Andrew S, Seder, Robert A
Publicado 2020

In vivo characterization of the physicochemical properties of TLR agonist delivery that enhance vaccine immunogenicity

por Lynn, Geoffrey M., Laga, Richard, Darrah, Patricia A., Ishizuka, Andrew S., Balaci, Alexandra J., Dulcey, Andrés E., Pechar, Michal, Pola, Robert, Gerner, Michael Y., Yamamoto, Ayako, Buechler, Connor R., Quinn, Kylie M., Smelkinson, Margery G., Vanek, Ondrej, Cawood, Ryan, Hills, Thomas, Vasalatiy, Olga, Kastenmuller, Kathrin, Francica, Joseph R., Stutts, Lalisa, Tom, Janine K., Ryu, Keun Ah, Esser-Kahn, Aaron P., Etrych, Tomas, Fisher, Kerry D., Seymour, Leonard W., Seder, Robert A.
Publicado 2015

Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T cell immunity to tumor antigens

por Lynn, Geoffrey M., Sedlik, Christine, Baharom, Faezzah, Zhu, Yaling, Ramirez-Valdez, Ramiro A., Coble, Vincent L., Tobin, Kennedy, Nichols, Sarah R., Itzkowitz, Yaakov, Zaidi, Neeha, Gammon, Joshua M., Blobel, Nicolas J., Denizeau, Jordan, de la Rochere, Philippe, Francica, Brian J., Decker, Brennan, Maciejewski, Mateusz, Cheung, Justin, Yamane, Hidehiro, Smelkinson, Margery G., Francica, Joseph R., Laga, Richard, Bernstock, Joshua D., Seymour, Leonard W., Drake, Charles G., Jewell, Christopher M., Lantz, Olivier, Piaggio, Eliane, Ishizuka, Andrew S., Seder, Robert A.
Publicado 2020

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

por Williams, Wilton B., Meyerhoff, R. Ryan, Edwards, R.J., Li, Hui, Manne, Kartik, Nicely, Nathan I., Henderson, Rory, Zhou, Ye, Janowska, Katarzyna, Mansouri, Katayoun, Gobeil, Sophie, Evangelous, Tyler, Hora, Bhavna, Berry, Madison, Abuahmad, A. Yousef, Sprenz, Jordan, Deyton, Margaret, Stalls, Victoria, Kopp, Megan, Hsu, Allen L., Borgnia, Mario J., Stewart-Jones, Guillaume B.E., Lee, Matthew S., Bronkema, Naomi, Moody, M. Anthony, Wiehe, Kevin, Bradley, Todd, Alam, S. Munir, Parks, Robert J., Foulger, Andrew, Oguin, Thomas, Sempowski, Gregory D., Bonsignori, Mattia, LaBranche, Celia C., Montefiori, David C., Seaman, Michael, Santra, Sampa, Perfect, John, Francica, Joseph R., Lynn, Geoffrey M., Aussedat, Baptiste, Walkowicz, William E., Laga, Richard, Kelsoe, Garnett, Saunders, Kevin O., Fera, Daniela, Kwong, Peter D., Seder, Robert A., Bartesaghi, Alberto, Shaw, George M., Acharya, Priyamvada, Haynes, Barton F.
Publicado 2021