Advances in preclinical evaluation of experimental antibody-drug conjugates

por Lyons, Scott K., Plenker, Dennis, Trotman, Lloyd C.
Publicado 2021

Oatp1 Enhances Bioluminescence by Acting as a Plasma Membrane Transporter for d-luciferin

por Patrick, P. Stephen, Lyons, Scott K., Rodrigues, Tiago B., Brindle, Kevin M.
Publicado 2014

Versatile and enhanced tumour modelling in mice via somatic cell transduction

por Rodriguez, Esther, Mannion, Liz, D'Santos, Paula, Griffiths, Meryl, Arends, Mark J, Brindle, Kevin M, Lyons, Scott K
Publicado 2014

Development of Timd2 as a reporter gene for MRI

por Patrick, P. Stephen, Rodrigues, Tiago B., Kettunen, Mikko I., Lyons, Scott K., Neves, André A., Brindle, Kevin M.
Publicado 2015

Internally Controlled and Dynamic Optical Measures of Functional Tumor Biology

por Chung, Taemoon, Garcia, Libia, Swamynathan, Manojit M., Froeling, Fieke E. M., Trotman, Lloyd C., Tuveson, David A., Lyons, Scott K.
Publicado 2023

Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response

por Merrill, Joseph R., Inguscio, Alessandra, Chung, Taemoon, Demestichas, Breanna, Garcia, Libia A., Habel, Jill, Lewis, David Y., Janowitz, Tobias, Lyons, Scott K.
Publicado 2023

[(18)F]fluoroethyltyrosine-induced Cerenkov Luminescence Improves Image-Guided Surgical Resection of Glioma

por Lewis, David Y., Mair, Richard, Wright, Alan, Allinson, Kieren, Lyons, Scott K., Booth, Tom, Jones, Julia, Bielik, Robert, Soloviev, Dmitry, Brindle, Kevin M.
Publicado 2018

Positron emission tomography imaging of the sodium iodide symporter senses real-time energy stress in vivo

por Dzien, Piotr, Mackintosh, Agata, Malviya, Gaurav, Johnson, Emma, Soloviev, Dmitry, Brown, Gavin, Uribe, Alejandro Huerta, Nixon, Colin, Lyons, Scott K., Maddocks, Oliver, Blyth, Karen, Lewis, David Y.
Publicado 2023

PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils

por Song, Dongyan, Adrover, Jose M., Felice, Christy, Christensen, Lisa N., He, Xue-Yan, Merrill, Joseph R., Wilkinson, John E., Janowitz, Tobias, Lyons, Scott K., Egeblad, Mikala, Tonks, Nicholas K.
Publicado 2022

Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection

por Adrover, Jose M., Carrau, Lucia, Daßler-Plenker, Juliane, Bram, Yaron, Chandar, Vasuretha, Houghton, Sean, Redmond, David, Merrill, Joseph R., Shevik, Margaret, tenOever, Benjamin R., Lyons, Scott K., Schwartz, Robert E., Egeblad, Mikala
Publicado 2022

Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53

por Kirschner, Kristina, Samarajiwa, Shamith A., Cairns, Jonathan M., Menon, Suraj, Pérez-Mancera, Pedro A., Tomimatsu, Kosuke, Bermejo-Rodriguez, Camino, Ito, Yoko, Chandra, Tamir, Narita, Masako, Lyons, Scott K., Lynch, Andy G., Kimura, Hiroshi, Ohbayashi, Tetsuya, Tavaré, Simon, Narita, Masashi
Publicado 2015

(13)C magnetic resonance spectroscopy measurements with hyperpolarized [1‐(13)C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo...

por Dzien, Piotr, Tee, Sui‐Seng, Kettunen, Mikko I., Lyons, Scott K., Larkin, Timothy J., Timm, Kerstin N., Hu, De‐En, Wright, Alan, Rodrigues, Tiago B., Serrao, Eva M., Marco‐Rius, Irene, Mannion, Elizabeth, D'Santos, Paula, Kennedy, Brett W. C., Brindle, Kevin M.
Publicado 2015

Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia

por Roberts, Edward W., Deonarine, Andrew, Jones, James O., Denton, Alice E., Feig, Christine, Lyons, Scott K., Espeli, Marion, Kraman, Matthew, McKenna, Brendan, Wells, Richard J.B., Zhao, Qi, Caballero, Otavia L., Larder, Rachel, Coll, Anthony P., O’Rahilly, Stephen, Brindle, Kevin M., Teichmann, Sarah A., Tuveson, David A., Fearon, Douglas T.
Publicado 2013

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer

por Lenos, Kristiaan J, Miedema, Daniël M, Lodestijn, Sophie C, Nijman, Lisanne E, van den Bosch, Tom, Romero Ros, Xavier, Lourenço, Filipe C, Lecca, Maria C, van der Heijden, Maartje, van Neerven, Sanne M, van Oort, Anita, Leveille, Nicolas, Adam, Ronja S, de Sousa E Melo, Felipe, Otten, Joy, Veerman, Patrick, Hypolite, Guillaume, Koens, Lianne, Lyons, Scott K, Stassi, Giorgio, Winton, Douglas J, Medema, Jan Paul, Morrissey, Edward, Bijlsma, Maarten F, Vermeulen, Louis
Publicado 2018