ABCA7 and the altered lipidostasis hypothesis of Alzheimer's disease

por Lyssenko, Nicholas N., Praticò, Domenico
Publicado 2020

Factors controlling nascent high-density lipoprotein particle heterogeneity: ATP-binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability

por Lyssenko, Nicholas N., Nickel, Margaret, Tang, Chongren, Phillips, Michael C.
Publicado 2013

An unexpectedly high degree of specialization and a widespread involvement in sterol metabolism among the C. elegans putative aminophospholipid translocases

por Lyssenko, Nicholas N, Miteva, Yana, Gilroy, Simon, Hanna-Rose, Wendy, Schlegel, Robert A
Publicado 2008

Down-Regulation of ABCA7 in Human Microglia, Astrocyte and THP-1 Cell Lines by Cholesterol Depletion, IL-1β and TNFα, or PMA

por Wiener, Joel P., Desire, Sindy, Garliyev, Viktor, Lyssenko III, Nicholas, Praticò, Domenico, Lyssenko, Nicholas N.
Publicado 2023

Mechanisms Responsible for the Compositional Heterogeneity of Nascent High Density Lipoprotein

por Lund-Katz, Sissel, Lyssenko, Nicholas N., Nickel, Margaret, Nguyen, David, Chetty, Palaniappan Sevugan, Weibel, Ginny, Phillips, Michael C.
Publicado 2013

Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics

por Khoshnejad, Makan, Patel, Ami, Wojtak, Krzysztof, Kudchodkar, Sagar B., Humeau, Laurent, Lyssenko, Nicholas N., Rader, Daniel J., Muthumani, Kar, Weiner, David B.
Publicado 2019

Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein

por Luthi, Andrea J., Lyssenko, Nicholas N., Quach, Duyen, McMahon, Kaylin M., Millar, John S., Vickers, Kasey C., Rader, Daniel J., Phillips, Michael C., Mirkin, Chad A., Thaxton, C. Shad
Publicado 2015

ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer’s disease

por Ko, Yi-An, Billheimer, Jeffrey T., Lyssenko, Nicholas N., Kueider-Paisley, Alexandra, Wolk, David A., Arnold, Steven E., Leung, Yuk Yee, Shaw, Leslie M., Trojanowski, John Q., Kaddurah-Daouk, Rima F., Kling, Mitchel A., Rader, Daniel J.
Publicado 2022

ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion

por Bi, Xin, Pashos, Evanthia E., Cuchel, Marina, Lyssenko, Nicholas N., Hernandez, Mayda, Picataggi, Antonino, McParland, James, Yang, Wenli, Liu, Ying, Yan, Ruilan, Yu, Christopher, DerOhannessian, Stephanie L., Phillips, Michael C., Morrisey, Edward E., Duncan, Stephen A., Rader, Daniel J.
Publicado 2017