Identification of suitable reference genes for normalization of reverse transcription quantitative real-time PCR (RT-qPCR) in the fibrotic phase of the bleomycin mouse model of pul...

por Norman, Oula, Koivunen, Jarkko, Mäki, Joni M., Pihlajaniemi, Taina, Heikkinen, Anne
Publicado 2022

Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium

por Dengler, Franziska, Sova, Sofia, Salo, Antti M., Mäki, Joni M., Koivunen, Peppi, Myllyharju, Johanna
Publicado 2021

Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways

por Ullah, Karim, Rosendahl, Ann-Helen, Izzi, Valerio, Bergmann, Ulrich, Pihlajaniemi, Taina, Mäki, Joni M., Myllyharju, Johanna
Publicado 2017

Prolyl hydroxylase domain 2 reduction enhances skeletal muscle tissue regeneration after soft tissue trauma in mice

por Settelmeier, Stephan, Schreiber, Timm, Mäki, Joni, Byts, Nadiya, Koivunen, Peppi, Myllyharju, Johanna, Fandrey, Joachim, Winning, Sandra
Publicado 2020

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

por Rosendahl, Ann-Helen, Monnius, Mia, Laitala, Anu, Railo, Antti, Miinalainen, Ilkka, Heljasvaara, Ritva, Mäki, Joni M., Myllyharju, Johanna
Publicado 2022

Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism

por Tapio, Joona, Halmetoja, Riikka, Dimova, Elitsa Y., Mäki, Joni M., Laitala, Anu, Walkinshaw, Gail, Myllyharju, Johanna, Serpi, Raisa, Koivunen, Peppi
Publicado 2022

PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis

por Elamaa, Harri, Kaakinen, Mika, Nätynki, Marjut, Szabo, Zoltan, Ronkainen, Veli-Pekka, Äijälä, Ville, Mäki, Joni M., Kerkelä, Risto, Myllyharju, Johanna, Eklund, Lauri
Publicado 2022

Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases

por Rachman-Tzemah, Chen, Zaffryar-Eilot, Shelly, Grossman, Moran, Ribero, Dario, Timaner, Michael, Mäki, Joni M., Myllyharju, Johanna, Bertolini, Francesco, Hershkovitz, Dov, Sagi, Irit, Hasson, Peleg, Shaked, Yuval
Publicado 2017

Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

por Martínez-Nieto, Guillermo A., Teppo, Hanna-Riikka, Petrelius, Noora, Izzi, Valerio, Devarajan, Raman, Petäistö, Tiina, Liu, Hengshuo, Kim, Kris S., Karppinen, Sanna-Maria, Ruotsalainen, Heli, Koivunen, Jarkko, Mäki, Joni M., Walker, Gilbert C., Pihlajaniemi, Taina, Gullberg, Donald, Heljasvaara, Ritva
Publicado 2022