Two-fold elevation of endogenous GDNF levels in mice improves motor coordination without causing side-effects

por Mätlik, Kärt, Võikar, Vootele, Vilenius, Carolina, Kulesskaya, Natalia, Andressoo, Jaan-Olle
Publicado 2018

Histone bivalency regulates the timing of cerebellar granule cell development

por Mätlik, Kärt, Govek, Eve-Ellen, Paul, Matthew R., Allis, C. David, Hatten, Mary E.
Publicado 2023

Histone bivalency regulates the timing of cerebellar granule cell development

por Mätlik, Kärt, Govek, Eve-Ellen, Paul, Matthew R., Allis, C. David, Hatten, Mary E.
Publicado 2023

In vivo modulation of endogenous gene expression via CRISPR/Cas9-mediated 3’UTR editing

por Mätlik, Kärt, Olfat, Soophie, Cowlishaw, Mark Cary, Moreno, Eva Domenech, Ollila, Saara, Andressoo, Jaan-Olle
Publicado 2023

Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers

por Mitra, Sumonto, Turconi, Giorgio, Darreh-Shori, Taher, Mätlik, Kärt, Aquilino, Matilde, Eriksdotter, Maria, Andressoo, Jaan-Olle
Publicado 2021

Increased Physiological GDNF Levels Have No Effect on Dopamine Neuron Protection and Restoration in a Proteasome Inhibition Mouse Model of Parkinson’s Disease

por Olfat, Soophie, Mätlik, Kärt, Kopra, Jaakko J., Garton, Daniel R., Iivanainen, Vilma H., Bhattacharya, Dipabarna, Jakobsson, Johan, Piepponen, T. Petteri, Andressoo, Jaan-Olle
Publicado 2023

Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF

por Li, Hao, Kurtzeborn, Kristen, Kupari, Jussi, Gui, Yujuan, Siefker, Edward, Lu, Benson, Mätlik, Kärt, Olfat, Soophie, Montaño-Rodríguez, Ana R., Huh, Sung-Ho, Costantini, Franklin, Andressoo, Jaan-Olle, Kuure, Satu
Publicado 2021

Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation

por Feng, Lijuan, Barrows, Douglas, Zhong, Liangwen, Mätlik, Kärt, Porter, Elizabeth G., Djomo, Annaelle M., Yau, Iris, Soshnev, Alexey A., Carroll, Thomas S., Wen, Duancheng, Hatten, Mary E., Garcia, Benjamin A., Allis, C. David
Publicado 2023

Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia

por Mätlik, Kärt, Garton, Daniel R., Montaño-Rodríguez, Ana R., Olfat, Soophie, Eren, Feride, Casserly, Laoise, Damdimopoulos, Anastasios, Panhelainen, Anne, Porokuokka, L. Lauriina, Kopra, Jaakko J., Turconi, Giorgio, Schweizer, Nadine, Bereczki, Erika, Piehl, Fredrik, Engberg, Göran, Cervenka, Simon, Piepponen, T. Petteri, Zhang, Fu-Ping, Sipilä, Petra, Jakobsson, Johan, Sellgren, Carl M., Erhardt, Sophie, Andressoo, Jaan-Olle
Publicado 2022