Studying epigenetic complexes and their inhibitors with the proteomics toolbox

por Weigt, David, Hopf, Carsten, Médard, Guillaume
Publicado 2016

Merits of Diazirine Photo-Immobilization for Target Profiling of Natural Products and Cofactors

por Prokofeva, Polina, Höfer, Stefanie, Hornisch, Maximilian, Abele, Miriam, Kuster, Bernhard, Médard, Guillaume
Publicado 2022

Targeted Diazotransfer Reagents Enable Selective Modification of Proteins with Azides

por Lohse, Jonas, Swier, Lotteke J.Y.M., Oudshoorn, Ruben C., Médard, Guillaume, Kuster, Bernhard, Slotboom, Dirk-Jan, Witte, Martin D.
Publicado 2017

N-Heterocyclic carbenes on close-packed coinage metal surfaces: bis-carbene metal adatom bonding scheme of monolayer films on Au, Ag and Cu

por Jiang, Li, Zhang, Bodong, Médard, Guillaume, Seitsonen, Ari Paavo, Haag, Felix, Allegretti, Francesco, Reichert, Joachim, Kuster, Bernhard, Barth, Johannes V., Papageorgiou, Anthoula C.
Publicado 2017

Snapshots of Dynamic Adaptation: Two‐Dimensional Molecular Architectonics with Linear Bis‐Hydroxamic Acid Modules

por Jing, Chao, Zhang, Bodong, Synkule, Sabine, Ebrahimi, Maryam, Riss, Alexander, Auwärter, Willi, Jiang, Li, Médard, Guillaume, Reichert, Joachim, Barth, Johannes V., Papageorgiou, Anthoula C.
Publicado 2019

Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid

por Lechner, Severin, Steimbach, Raphael R., Wang, Longlong, Deline, Marshall L., Chang, Yun-Chien, Fromme, Tobias, Klingenspor, Martin, Matthias, Patrick, Miller, Aubry K., Médard, Guillaume, Kuster, Bernhard
Publicado 2023

N‐Heterocyclic Carbenes: Molecular Porters of Surface Mounted Ru‐Porphyrins

por Knecht, Peter, Meier, Dennis, Reichert, Joachim, Duncan, David A., Schwarz, Martin, Küchle, Johannes T., Lee, Tien‐Lin, Deimel, Peter S., Feulner, Peter, Allegretti, Francesco, Auwärter, Willi, Médard, Guillaume, Seitsonen, Ari Paavo, Barth, Johannes V., Papageorgiou, Anthoula C.
Publicado 2022

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

por Schneider, Katharina S., Groß, Christina J., Dreier, Roland F., Saller, Benedikt S., Mishra, Ritu, Gorka, Oliver, Heilig, Rosalie, Meunier, Etienne, Dick, Mathias S., Ćiković, Tamara, Sodenkamp, Jan, Médard, Guillaume, Naumann, Ronald, Ruland, Jürgen, Kuster, Bernhard, Broz, Petr, Groß, Olaf
Publicado 2017

Development of selective inhibitors of phosphatidylinositol 3-kinase C2α

por Lo, Wen-Ting, Belabed, Hassane, Kücükdisli, Murat, Metag, Juliane, Roske, Yvette, Prokofeva, Polina, Ohashi, Yohei, Horatscheck, André, Cirillo, Davide, Krauss, Michael, Schmied, Christopher, Neuenschwander, Martin, von Kries, Jens Peter, Médard, Guillaume, Kuster, Bernhard, Perisic, Olga, Williams, Roger L., Daumke, Oliver, Payrastre, Bernard, Severin, Sonia, Nazaré, Marc, Haucke, Volker
Publicado 2022

Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum

por Nardella, Flore, Dobrescu, Irina, Hassan, Haitham, Rodrigues, Fabien, Thiberge, Sabine, Mancio-Silva, Liliana, Tafit, Ambre, Jallet, Corinne, Cadet-Daniel, Véronique, Goussin, Stéphane, Lorthiois, Audrey, Menon, Yoann, Molinier, Nicolas, Pechalrieu, Dany, Long, Christophe, Sautel, François, Matondo, Mariette, Duchateau, Magalie, Médard, Guillaume, Witkowski, Benoit, Scherf, Artur, Halby, Ludovic, Arimondo, Paola B.
Publicado 2023

Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target

por Lechner, Severin, Malgapo, Martin Ian P., Grätz, Christian, Steimbach, Raphael R., Baron, Agnes, Rüther, Patrick, Nadal, Simon, Stumpf, Carmen, Loos, Christina, Ku, Xin, Prokofeva, Polina, Lautenbacher, Ludwig, Heimburg, Tino, Würf, Vivian, Meng, Chen, Wilhelm, Mathias, Sippl, Wolfgang, Kleigrewe, Karin, Pauling, Josch K., Kramer, Karl, Miller, Aubry K., Pfaffl, Michael W., Linder, Maurine E., Kuster, Bernhard, Médard, Guillaume
Publicado 2022