Phosphoproteomic analysis of metformin signaling in colorectal cancer cells elucidates mechanism of action and potential therapeutic opportunities

por Salovska, Barbora, Gao, Erli, Müller‐Dott, Sophia, Li, Wenxue, Cordon, Carlos Chacon, Wang, Shisheng, Dugourd, Aurelien, Rosenberger, George, Saez‐Rodriguez, Julio, Liu, Yansheng
Publicado 2023

Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities

por Müller-Dott, Sophia, Tsirvouli, Eirini, Vazquez, Miguel, Ramirez Flores, Ricardo O, Badia-i-Mompel, Pau, Fallegger, Robin, Türei, Dénes, Lægreid, Astrid, Saez-Rodriguez, Julio
Publicado 2023

decoupleR: ensemble of computational methods to infer biological activities from omics data

por Badia-i-Mompel, Pau, Vélez Santiago, Jesús, Braunger, Jana, Geiss, Celina, Dimitrov, Daniel, Müller-Dott, Sophia, Taus, Petr, Dugourd, Aurelien, Holland, Christian H, Ramirez Flores, Ricardo O, Saez-Rodriguez, Julio
Publicado 2022

Hepatocytes reprogram liver macrophages involving control of TGF-β activation, influencing liver regeneration and injury

por Wolf, Stephanie D., Ehlting, Christian, Müller-Dott, Sophia, Poschmann, Gereon, Petzsch, Patrick, Lautwein, Tobias, Wang, Sai, Helm, Barbara, Schilling, Marcel, Saez-Rodriguez, Julio, Vucur, Mihael, Stühler, Kai, Köhrer, Karl, Tacke, Frank, Dooley, Steven, Klingmüller, Ursula, Luedde, Tom, Bode, Johannes G.
Publicado 2023